دورية أكاديمية
Cross-sectional assessment of three commonly used measures of adherence to combination antiviral therapy in a resource limited setting.
| العنوان: | Cross-sectional assessment of three commonly used measures of adherence to combination antiviral therapy in a resource limited setting. |
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| المؤلفون: | Luma HN; 1 Internal Medicine Unit, Douala General Hospital, Douala, Cameroon.; 2 Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon., Mbatchou Ngahane BH; 1 Internal Medicine Unit, Douala General Hospital, Douala, Cameroon.; 3 Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon., Mapoure YN; 1 Internal Medicine Unit, Douala General Hospital, Douala, Cameroon.; 3 Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon., Mengjo NB; 4 Faculty of Health Sciences, University of Buea, Buea, Cameroon., Temfack E; 1 Internal Medicine Unit, Douala General Hospital, Douala, Cameroon.; 5 Paris Descartes University, Paris, France., Joko HA; 1 Internal Medicine Unit, Douala General Hospital, Douala, Cameroon., Asongalem EA; 2 Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon., Koulla-Shiro S; 2 Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon. |
| المصدر: | International journal of STD & AIDS [Int J STD AIDS] 2017 Jan; Vol. 28 (1), pp. 69-76. Date of Electronic Publication: 2016 Jul 11. |
| نوع المنشور: | Evaluation Study; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Sage Country of Publication: England NLM ID: 9007917 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1758-1052 (Electronic) Linking ISSN: 09564624 NLM ISO Abbreviation: Int J STD AIDS Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Dec. 2012- : London : Sage Original Publication: London, U.K. : Royal Society of Medicine Services, c1990- |
| مواضيع طبية MeSH: | Medication Adherence*, Anti-HIV Agents/*therapeutic use , Antiretroviral Therapy, Highly Active/*methods , HIV Infections/*drug therapy, Adolescent ; Adult ; Cameroon/epidemiology ; Cross-Sectional Studies ; Female ; Follow-Up Studies ; HIV Infections/epidemiology ; HIV Infections/psychology ; HIV-1 ; Humans ; Middle Aged ; Visual Analog Scale ; Young Adult |
| مستخلص: | Nowadays, global coverage of combination antiretroviral therapy (cART) has increased due to a continuous process to scale up access. This increase has potentially transformed HIV-infection from a fatal to a chronic disease: a transformation only possible if the prescribed medications are taken accordingly. We therefore evaluated optimal adherence to cART by three commonly used methods: visual analogue scale (VAS), four days recall (FDR) and clinic attendance (CA) for the last six months in 301 HIV-infected patients on cART for at least six months at the Douala General Hospital, Cameroon. Optimal adherence was defined to be greater than or equal to the 95th percentile estimate of each method. We found that 70.8% of our study population was female. The mean age was 40.8 years (SD 10.5) and 85% were on first line cART. Median CD4 count was 397 cells/ml (252-559). Optimal adherence by VAS, FDR and CA, was 68.1%, 83.4%, and 73.4%, respectively. VAS and FDR inter-correlated strongly (Pearson's Chi square coefficient, r = 0.58, p < 0.001). Higher CD4 count above 200 cells/ml was associated with optimal adherence by CA (Adjusted Odds Ratio [AOR]:2.6 (95% CI: 1.2-5.3, p < 0.001)). As high optimal adherence to cART is associated with good clinical outcome in HIV patients, simple methods such as the VAS for evaluating adherence, should be integrated to the HIV clinic of the Douala General Hospital. |
| فهرسة مساهمة: | Keywords: Adherence; clinic attendance; four day recall; visual analogue scale |
| المشرفين على المادة: | 0 (Anti-HIV Agents) |
| تواريخ الأحداث: | Date Created: 20160110 Date Completed: 20170717 Latest Revision: 20191210 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1177/0956462415627394 |
| PMID: | 26748336 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1758-1052 |
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| DOI: | 10.1177/0956462415627394 |