دورية أكاديمية
Stability indicating methods for the analysis of cefprozil in the presence of its alkaline induced degradation product.
| العنوان: | Stability indicating methods for the analysis of cefprozil in the presence of its alkaline induced degradation product. |
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| المؤلفون: | Attia KA; Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Al-Azhar University, 11751 Nasr City, Cairo, Egypt., Nassar MW; Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Al-Azhar University, 11751 Nasr City, Cairo, Egypt., El-Zeiny MB; Analytical Chemistry Department, Faculty of Pharmacy, Modern University for Technology and Information (MTI), 12582 Al Hadaba Al Wosta, Cairo, Egypt., Serag A; Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Al-Azhar University, 11751 Nasr City, Cairo, Egypt. Electronic address: Ahmedserag777@hotmail.com. |
| المصدر: | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy [Spectrochim Acta A Mol Biomol Spectrosc] 2016 Apr 15; Vol. 159, pp. 1-6. Date of Electronic Publication: 2016 Jan 21. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: England NLM ID: 9602533 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3557 (Electronic) Linking ISSN: 13861425 NLM ISO Abbreviation: Spectrochim Acta A Mol Biomol Spectrosc Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Original Publication: [Kidlington, Oxford, U.K. ; Tarrytown, NY] : Pergamon, c1994- |
| مواضيع طبية MeSH: | Anti-Bacterial Agents/*chemistry , Cephalosporins/*chemistry , Spectrophotometry/*methods, Algorithms ; Alkalies/chemistry ; Drug Stability ; Least-Squares Analysis ; Multivariate Analysis ; Cefprozil |
| مستخلص: | Three simple, specific, accurate and precise spectrophotometric methods were developed for the determination of cefprozil (CZ) in the presence of its alkaline induced degradation product (DCZ). The first method was the bivariate method, while the two other multivariate methods were partial least squares (PLS) and spectral residual augmented classical least squares (SRACLS). The multivariate methods were applied with and without variable selection procedure (genetic algorithm GA). These methods were tested by analyzing laboratory prepared mixtures of the above drug with its alkaline induced degradation product and they were applied to its commercial pharmaceutical products. (Copyright © 2016 Elsevier B.V. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Bivariate; Cefprozil; Genetic algorithm; PLS; SRACLS; Stability indicating methods |
| المشرفين على المادة: | 0 (Alkalies) 0 (Anti-Bacterial Agents) 0 (Cephalosporins) |
| تواريخ الأحداث: | Date Created: 20160128 Date Completed: 20161108 Latest Revision: 20231213 |
| رمز التحديث: | 20240829 |
| DOI: | 10.1016/j.saa.2016.01.026 |
| PMID: | 26814624 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1873-3557 |
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| DOI: | 10.1016/j.saa.2016.01.026 |