دورية أكاديمية
Evaluation of peripheral lymphadenopathy with excisional biopsy: six-year experience.
| العنوان: | Evaluation of peripheral lymphadenopathy with excisional biopsy: six-year experience. |
|---|---|
| المؤلفون: | Özkan EA; Department of Pediatrics, Faculty of Medical, Bozok University Yozgat, Turkey., Göret CC; Department of Pathology, Haydarpasa Numune Training and Research Hospital Istanbul, Turkey., Özdemir ZT; Department of Internal Medicine, Faculty of Medical, Bozok University Yozgat, Turkey., Yanık S; Department of Pathology, Iskenderun State Hospital Hatay, Turkey., Göret NE; Department of General Surgery, Kartal Dr Lütfü Kırdar Training and Research Hospital Istanbul, Turkey., Doğan M; Department of Pathology, Faculty of Medical, Atatürk University Erzurum, Turkey., Cihan FG; Department of Family Medicine, Faculty of Medical, Necmettin Erbakan University Konya, Turkey., Akkoca AN; Department of Family Medicine, Iskenderun State Hospital Hatay, Turkey. |
| المصدر: | International journal of clinical and experimental pathology [Int J Clin Exp Pathol] 2015 Nov 01; Vol. 8 (11), pp. 15234-9. Date of Electronic Publication: 2015 Nov 01 (Print Publication: 2015). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: e-Century Pub. Corp Country of Publication: United States NLM ID: 101480565 Publication Model: eCollection Cited Medium: Internet ISSN: 1936-2625 (Electronic) Linking ISSN: 19362625 NLM ISO Abbreviation: Int J Clin Exp Pathol Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Madison, WI : e-Century Pub. Corp., [2008]- |
| مواضيع طبية MeSH: | Lymph Node Excision*, Lymph Nodes/*pathology , Lymph Nodes/*surgery , Lymphatic Diseases/*pathology , Lymphatic Diseases/*surgery, Adolescent ; Adult ; Aged ; Aged, 80 and over ; Biopsy ; Child ; Child, Preschool ; Diagnosis, Differential ; Female ; Humans ; Infant ; Male ; Middle Aged ; Predictive Value of Tests ; Retrospective Studies ; Turkey ; Young Adult |
| مستخلص: | Background: Lymphadenopathy (LAP) may be the first symptom of many diseases. We aimed to investigate peripheral LAP results taken by excisional biopsy. Methods: Histopathological examination of 185 lymph node biopsy specimens were evaluated between January 2009 and April 2015 in Istanbul Private Ekin Pathology Laboratory, retrospectively. Results: The average age of patients ranged from 1 to 86 was 41.01 ± 20.62 years. 87 of were female, 98 of male. 62 (33.5%) of excisional biopsy materials were benign lesions and 123 (66.5%) of malignant. Benign lesions were consisted of reactive hyperplasia, cat-scratch disease, toxoplasmosis, necrotizing/non-necrotizing granulomatous. Of these patients, 40 had nodes with reactive hyperplasia (15 female/25 male, mean age: 27.35 y), 14 had necrotizing granulomatous disease (9 female/5 male, mean age: 39.86 y), 2 non-necrotizing granulomatous disease (1 female/1 male mean age: 43 y), 4 had cat-scratch disease (1 female/3 male mean age: 54.25 y), 1 toxoplasmosis (26 y, female), 1 Kikuchi disease (25 y, female). In the evaluation of malign lesions; 38 were Hodgkin lymphoma (HL) (20.5%, 17 female/21 male, mean age: 34.89 y) 77 had non-Hodgkin lymphoma (NHL) (41.6%, 37 female/40 male, mean age: 52.26 y), 8 metastasis (4.3%, 5 female/3 male, mean age: 53.5 y). Reactive LAP observed most common in cervical region, NHL in axillary-abdomen-inguinal-mediastinum and HL in the supraclavicular region. Conclusion: Excisional biopsy can be applied safely with minimal morbidity and mortality and a gold standard diagnostic method for LAP. Although LAP is mostly related with benign lesions, malignancy should be kept in mind in differential diagnosis. |
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| فهرسة مساهمة: | Keywords: Benign; excisional biopsy; lymphadenopathy; malignant |
| تواريخ الأحداث: | Date Created: 20160130 Date Completed: 20161024 Latest Revision: 20220317 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC4713658 |
| PMID: | 26823872 |
| قاعدة البيانات: | MEDLINE |
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