دورية أكاديمية
EFFECT OF PRE-OPERATIVE SUB-LINGUAL MISOPROSTOL VERSUS INTRAVENOUS OXYTOCIN ON CAESAREAN OPERATION BLOOD LOSS.
| العنوان: | EFFECT OF PRE-OPERATIVE SUB-LINGUAL MISOPROSTOL VERSUS INTRAVENOUS OXYTOCIN ON CAESAREAN OPERATION BLOOD LOSS. |
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| المؤلفون: | Adefuye PO; Department of Obstetrics and Gynaecology, Olabisi Onabanjo University Teaching Hospital, Sagamu, Ogun State, Nigeria., Akindele RA, Adefuye BO, Durojaiye BO, Adeiyi TO |
| المصدر: | East African medical journal [East Afr Med J] 2012 Sep; Vol. 89 (9), pp. 294-300. |
| نوع المنشور: | Comparative Study; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Medical Association of East Africa Country of Publication: Kenya NLM ID: 0372766 Publication Model: Print Cited Medium: Print ISSN: 0012-835X (Print) Linking ISSN: 0012835X NLM ISO Abbreviation: East Afr Med J Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Nairobi Medical Association of East Africa |
| مواضيع طبية MeSH: | Cesarean Section*, Blood Loss, Surgical/*prevention & control , Misoprostol/*administration & dosage , Oxytocics/*administration & dosage , Oxytocin/*administration & dosage, Administration, Sublingual ; Adult ; Female ; Hematocrit ; Humans ; Injections, Intravenous ; Misoprostol/adverse effects ; Oxytocics/adverse effects ; Pregnancy ; Preoperative Care ; Prospective Studies ; Treatment Outcome |
| مستخلص: | Background: Caesarean operation remains the most common abdominal surgery in women and has immense benefits to both mother and baby when employed. Haemorrhage, however, remains the greatest challenge associated with its outcome. Objective: To compare the effectiveness of pre-operative sub-lingual misoprostol with intravenous oxytocin administered after delivery of the neonate in minimising blood loss at Caesarean operation. Design: A prospective study. Results: The mean blood loss was significantly lower in misoprostol group compared to oxytocin group (517.32mls versus 621.22mls; p = 0.005). The drop in haematocrit was significantly lower in misoprostol group than the oxytocin group, (400 μg-misoprostol versus oxytocin: 1.88 versus 3.04; p = 0.0001). Side effects of chills, shivering and pyrexia were noted more with the use of misoprostol. Conclusion: Pre-operative sub-lingual misoprostol is more effective than intravenous infusion of oxytocin in reducing blood loss at Caesarean section operation. However, occurrence of transient side effects of chills, shivering and pyrexia were noted more with use of misoprostol. |
| المشرفين على المادة: | 0 (Oxytocics) 0E43V0BB57 (Misoprostol) 50-56-6 (Oxytocin) |
| تواريخ الأحداث: | Date Created: 20160209 Date Completed: 20160309 Latest Revision: 20160208 |
| رمز التحديث: | 20240829 |
| PMID: | 26852436 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0012-835X |
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