دورية أكاديمية
أعرض في EDS

Effect of continuous and interval aerobic exercise training on baroreflex sensitivity in heart failure.

التفاصيل البيبلوغرافية
العنوان: Effect of continuous and interval aerobic exercise training on baroreflex sensitivity in heart failure.
المؤلفون: Masson GS; Laboratory of Cardiovascular Investigation, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, RJ, Brazil., Borges JP; Laboratory of Cardiovascular Investigation, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, RJ, Brazil; Laboratory of Physical Activity and Health Promotion, State University of Rio de Janeiro, Brazil. Electronic address: julipborges@gmail.com., da Silva PP; Department of Physiology and Pharmacology, Fluminense Federal University, Niterói, RJ, Brazil., da Nóbrega AC; Department of Physiology and Pharmacology, Fluminense Federal University, Niterói, RJ, Brazil., Tibiriçá E; Laboratory of Cardiovascular Investigation, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, RJ, Brazil., Lessa MA; Laboratory of Cardiovascular Investigation, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, RJ, Brazil.
المصدر: Autonomic neuroscience : basic & clinical [Auton Neurosci] 2016 May; Vol. 197, pp. 9-13. Date of Electronic Publication: 2016 Mar 10.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 100909359 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7484 (Electronic) Linking ISSN: 15660702 NLM ISO Abbreviation: Auton Neurosci Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [Amsterdam ; New York] : Elsevier, c2000-
مواضيع طبية MeSH: Baroreflex/*physiology , Heart Failure/*physiopathology, Animals ; Autonomic Nervous System/physiopathology ; Blood Pressure/physiology ; Heart Rate/drug effects ; Kidney/physiopathology ; Male ; Physical Conditioning, Animal ; Rats, Wistar ; Sympathetic Nervous System/physiopathology
مستخلص: Introduction: The ability of continuous aerobic exercise training (AET) to increase baroreflex control and cardiac function in heart failure (HF) has been well described, but the comparison between continuous and interval AET on these functions is inconclusive.
Objectives: To compare the effects of continuous and interval AET on cardiac function and baroreflex sensitivity (BrS) in an experimental model of HF.
Methods: Rats were divided into the following groups: continuous training (HF-CT), intense interval training (HF-IIT), moderate interval training (HF-MIT), sedentary group (HF-SED), and sham sedentary (SHAM-SED). Animals underwent surgery to induce HF by ligation of the interventricular coronary artery. Six weeks after surgery, AET was started (8weeks, 3sessions/week). Echocardiography studies to assess cardiac function were performed before and after AET. At the end of the training protocols, the BrS index was assessed by stepwise intravenous infusions of sodium nitroprusside and phenylephrine.
Results: All methods of exercise prevented the HF-induced increase in left ventricular diameter in diastole observed in the HF-SED rats (0.88±0.09 vs. 1.03±0.09cm; P<0.05), but only the HF-CT (28.5±6.3 vs. 39.2±12.7%; P<0.05) and HF-MIT (31.0±8.5 vs. 42.0±10.3%; P<0.05) groups exhibited an increase in ejection fraction. Nevertheless, the HF-CT group was the only group that showed a tachycardia reflex higher than that of the HF-SED group (0.87±0.34 vs. 0.20±0.05bpm/mmHg; P<0.05) and similar to that of the SHAM-SED group (1.04±0.11bpm/mmHg).
Conclusions: These results suggest that continuous and moderate interval training induced similar improvements in cardiac function but that only continuous training induced higher BrS in HF rats.
(Copyright © 2016 Elsevier B.V. All rights reserved.)
فهرسة مساهمة: Keywords: Arterial baroreflex; Cardiac function; Exercise
تواريخ الأحداث: Date Created: 20160319 Date Completed: 20170926 Latest Revision: 20180308
رمز التحديث: 20231215
DOI: 10.1016/j.autneu.2016.03.003
PMID: 26987408
قاعدة البيانات: MEDLINE
الوصف
تدمد:1872-7484
DOI:10.1016/j.autneu.2016.03.003