دورية أكاديمية

Endoscopic band ligation without resection in selected patients for small and superficial upper gastrointestinal tract lesions.

التفاصيل البيبلوغرافية
العنوان: Endoscopic band ligation without resection in selected patients for small and superficial upper gastrointestinal tract lesions.
المؤلفون: Ibáñez-Sanz G; Gastroenterología, Hospital Universitari de Bellvitge-IDIBELL, España., Gornals JB; Endoscopia/Aparato Digestivo, Hospital Universitari de Bellvitge, España., Rivas L; Hospital Universitari de Bellvitge-IDIBELL., Salord S; Hospital Universitari de Bellvitge-IDIBELL., Paúles MJ; Hospital Universitari de Bellvitge-IDIBELL., Botargues JM; Hospital Universitari de Bellvitge-IDIBELL., Galán M; Institut Català d'Oncologia DiR-IDIBELL.
المصدر: Revista espanola de enfermedades digestivas [Rev Esp Enferm Dig] 2016 May; Vol. 108 (5), pp. 250-6.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Aran Ediciones Country of Publication: Spain NLM ID: 9007566 Publication Model: Print Cited Medium: Internet ISSN: 1130-0108 (Print) Linking ISSN: 11300108 NLM ISO Abbreviation: Rev Esp Enferm Dig Subsets: MEDLINE
أسماء مطبوعة: Publication: 2001- : Madrid : Aran Ediciones
Original Publication: Madrid : Editorial Garsi, [1990-
مواضيع طبية MeSH: Endoscopy, Gastrointestinal/*methods , Gastrointestinal Diseases/*surgery , Upper Gastrointestinal Tract/*surgery, Aged ; Aged, 80 and over ; Female ; Gastrointestinal Neoplasms/surgery ; Humans ; Ligation ; Male ; Middle Aged ; Retrospective Studies ; Treatment Outcome
مستخلص: Background and Aim: The aim of this study was to evaluate the efficacy of endoscopic band ligation (EBL) in carefully selected patients who would benefit from this method of resection.
Methods: Patients with early upper gastrointestinal and small (< 15 mm) lesions treated with EBL (Duette® Multi-Band Mucosectomy) were prospectively recruited and retrospectively analyzed between 2010 and 2015. All cases were discussed in a multidisciplinary cancer committee and it was concluded that, owing to patient conditions, surgery was not possible and that not conducting histology would not change the clinical management. A first endoscopic control with biopsies was planned at 4-8 weeks. If there was no persistence of the lesion, new controls were programmed at 6 and 12 months.
Results: The group (n = 12) included 5 esophagus lesions (adenosquamous carcinoma, n = 1; carcinoma squamous, n = 2; adenocarcinoma, n = 2); 4 gastric lesions (high grade dysplasia, n = 1; adenocarcinoma, n = 2; neuroendocrine tumor [NET], n = 1), and 3 duodenal lesions (NETs) (n = 3). The mean tumor diameter was 9.6 ± 2.8 mm (range 4-15). Only one minor adverse event was described. At first follow-up (4-8 weeks), there was 91.6% and 75% of endoscopic and histological remission, respectively. At 6-month follow-up there was 70% of both endoscopic remission and negative biopsies. And at 12 months, there was 100% and 75% of endoscopic and histological remission, respectively. Persisting lesions were T1 cancers. The median follow-up was 30.6 months.
Conclusion: EBL without resection is an easy and safe technique that should be considered in patients with multiple morbidities and small superficial UGI lesions.
تواريخ الأحداث: Date Created: 20160330 Date Completed: 20170405 Latest Revision: 20170405
رمز التحديث: 20231215
DOI: 10.17235/reed.2016.4031/2015
PMID: 27022723
قاعدة البيانات: MEDLINE
الوصف
تدمد:1130-0108
DOI:10.17235/reed.2016.4031/2015