دورية أكاديمية
أعرض في EDS

Healthy individuals maintain adaptive stimulus evaluation under predictable and unpredictable threat.

التفاصيل البيبلوغرافية
العنوان: Healthy individuals maintain adaptive stimulus evaluation under predictable and unpredictable threat.
المؤلفون: Klinkenberg IA; Institute for Biomagnetism and Biosignalanalysis, University Hospital Muenster, D-48149 Muenster, Germany; Otto Creutzfeldt Center for Cognitive and Behavioral Neuroscience, University of Muenster, Muenster, Germany. Electronic address: i.klinkenberg@uni-muenster.de., Rehbein MA; Institute for Biomagnetism and Biosignalanalysis, University Hospital Muenster, D-48149 Muenster, Germany; Otto Creutzfeldt Center for Cognitive and Behavioral Neuroscience, University of Muenster, Muenster, Germany., Steinberg C; Institute for Biomagnetism and Biosignalanalysis, University Hospital Muenster, D-48149 Muenster, Germany., Klahn AL; Department of Psychiatry, Mood and Anxiety Disorders Research Unit, University Hospital Muenster, D-48149 Muenster, Germany., Zwanzger P; kbo-Inn-Salzach-Klinikum, D-83512 Wasserburg am Inn, Germany., Zwitserlood P; Otto Creutzfeldt Center for Cognitive and Behavioral Neuroscience, University of Muenster, Muenster, Germany; Institute of Psychology, University of Muenster, D-48149 Muenster, Germany., Junghöfer M; Institute for Biomagnetism and Biosignalanalysis, University Hospital Muenster, D-48149 Muenster, Germany; Otto Creutzfeldt Center for Cognitive and Behavioral Neuroscience, University of Muenster, Muenster, Germany.
المصدر: NeuroImage [Neuroimage] 2016 Aug 01; Vol. 136, pp. 174-85. Date of Electronic Publication: 2016 May 18.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 9215515 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9572 (Electronic) Linking ISSN: 10538119 NLM ISO Abbreviation: Neuroimage Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Orlando, FL : Academic Press, c1992-
مواضيع طبية MeSH: Facial Expression*, Adaptation, Physiological/*physiology , Anticipation, Psychological/*physiology , Fear/*physiology , Nerve Net/*physiology , Prefrontal Cortex/*physiology, Adolescent ; Brain Mapping ; Fear/psychology ; Female ; Humans ; Male ; Reference Values ; Young Adult
مستخلص: The anxiety inducing paradigms such as the threat-of-shock paradigm have provided ample data on the emotional processing of predictable and unpredictable threat, but little is known about the processing of aversive, threat-irrelevant stimuli in these paradigms. We investigated how the predictability of threat influences the neural visual processing of threat-irrelevant fearful and neutral faces. Thirty-two healthy individuals participated in an NPU-threat test, consisting of a safe or neutral condition (N) and a predictable (P) as well as an unpredictable (U) threat condition, using audio-visual threat stimuli. In all NPU-conditions, we registered participants' brain responses to threat-irrelevant faces via magnetoencephalography. The data showed that increasing unpredictability of threat evoked increasing emotion regulation during face processing predominantly in dorsolateral prefrontal cortex regions during an early to mid-latency time interval. Importantly, we obtained only main effects but no significant interaction of facial expression and conditions of different threat predictability, neither in behavioral nor in neural data. Healthy individuals with average trait anxiety are thus able to maintain adaptive stimulus evaluation processes under predictable and unpredictable threat conditions.
(Copyright © 2016 Elsevier Inc. All rights reserved.)
فهرسة مساهمة: Keywords: Electroencephalography (EEG); Fronto-parietal network; MEG; Phasic fear; Sustained anxiety; dlPFC
تواريخ الأحداث: Date Created: 20160522 Date Completed: 20180123 Latest Revision: 20180123
رمز التحديث: 20221213
DOI: 10.1016/j.neuroimage.2016.05.041
PMID: 27208859
قاعدة البيانات: MEDLINE
الوصف
تدمد:1095-9572
DOI:10.1016/j.neuroimage.2016.05.041