دورية أكاديمية
Interview-based assessment of cognition is a strong predictor of quality of life in patients with schizophrenia and severe negative symptoms.
| العنوان: | Interview-based assessment of cognition is a strong predictor of quality of life in patients with schizophrenia and severe negative symptoms. |
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| المؤلفون: | Cruz BF; Programa de Pós-Graduação em Neurociências, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil., Resende CB; Grupo de Pesquisa em Psiquiatria e Cognição, Instituto Raul Soares, Fundação Hospitalar do Estado de Minas Gerais (FHEMIG), Belo Horizonte, MG, Brazil., Carvalhaes CF; Instituto de Previdência dos Servidores do Estado de Minas Gerais (IPSEMG), Belo Horizonte, MG, Brazil., Cardoso CS; Departamento de Epidemiologia, Universidade Federal de São João del-Rei (UFSJ), São João del-Rei, MG, Brazil., Teixeira AL; Programa de Pós-Graduação em Neurociências, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil.; Departamento de Medicina Interna, UFMG, Belo Horizonte, MG, Brazil., Keefe RS; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA., Rocha FL; Instituto de Previdência dos Servidores do Estado de Minas Gerais (IPSEMG), Belo Horizonte, MG, Brazil., Salgado JV; Programa de Pós-Graduação em Neurociências, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil.; Grupo de Pesquisa em Psiquiatria e Cognição, Instituto Raul Soares, Fundação Hospitalar do Estado de Minas Gerais (FHEMIG), Belo Horizonte, MG, Brazil.; Departamento de Morfologia, UFMG, Belo Horizonte, MG, Brazil. |
| المصدر: | Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) [Braz J Psychiatry] 2016 Jul-Sep; Vol. 38 (3), pp. 216-21. Date of Electronic Publication: 2016 Jun 14. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Associação Brasileira de Psiquiatria Country of Publication: Brazil NLM ID: 100895975 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1809-452X (Electronic) Linking ISSN: 15164446 NLM ISO Abbreviation: Braz J Psychiatry Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: São Paulo, SP, Brasil : Associação Brasileira de Psiquiatria, [1999]- |
| مواضيع طبية MeSH: | Psychiatric Status Rating Scales*, Cognitive Dysfunction/*physiopathology , Quality of Life/*psychology , Schizophrenia/*physiopathology, Adult ; Analysis of Variance ; Brazil ; Female ; Humans ; Male ; Middle Aged ; Neuropsychological Tests ; Predictive Value of Tests ; Psychometrics ; Reproducibility of Results ; Schizophrenia/diagnosis ; Schizophrenic Psychology ; Severity of Illness Index ; Statistics, Nonparametric |
| مستخلص: | Objective: To analyze the correlation between quality of life, symptoms, and cognition assessed by the interview-based Schizophrenia Cognition Rating Scale (SCoRS). Methods: Seventy-nine outpatients diagnosed with schizophrenia were evaluated with the Quality of Life Scale - Brazilian version (QLS-BR), the SCoRS, and symptoms scales (Positive and Negative Syndrome Scale [PANSS]). After determining the potential explanatory variables using Spearman's correlation and Student's t test results, we ran simple, multivariate, and decision-tree regression analyses to assess the impact of SCoRS and PANSS ratings on mean overall quality of life. Results: Cognitive deficits and negative symptoms were the best predictors of quality of life. A low degree of negative symptoms (PANSS negative < 11) was a strong predictor of better quality of life (QLS ∼ 75), regardless of SCoRS rating. Among participants with more severe negative symptoms, elevated cognitive impairment (interviewer SCoRS ∼ 44) was a predictor of worse quality of life (QLS ∼ 44). Conclusions: Cognitive impairment determined by interview-based assessment seems to be a strong predictor of quality of life in subjects with severe negative symptoms. These results support the usefulness of SCoRS for cognitive assessment that is relevant to the everyday life of patients with schizophrenia. |
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| تواريخ الأحداث: | Date Created: 20160616 Date Completed: 20170403 Latest Revision: 20200505 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC7194260 |
| DOI: | 10.1590/1516-4446-2015-1776 |
| PMID: | 27304257 |
| قاعدة البيانات: | MEDLINE |
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