دورية أكاديمية
The spectrum of congenital heart diseases in down syndrome. A retrospective study from Northwest Saudi Arabia.
| العنوان: | The spectrum of congenital heart diseases in down syndrome. A retrospective study from Northwest Saudi Arabia. |
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| المؤلفون: | Morsy MM; Department of Pediatric Cardiology, Madina Cardiac Center, Madinah, Kingdom of Saudi Arabia. E-mail. mofeedfawaz@gmail.com., Algrigri OO, Salem SS, Abosedera MM, Abutaleb AR, Al-Harbi KM, Al-Mozainy IS, Alnajjar AA, Habeb AM, Abo-Haded HM |
| المصدر: | Saudi medical journal [Saudi Med J] 2016 Jul; Vol. 37 (7), pp. 767-72. |
| نوع المنشور: | Journal Article; Comment |
| اللغة: | English |
| بيانات الدورية: | Publisher: Medical Services Department, Saudi Arabian Armed Forces, Ministry Of Defence And Aviation Country of Publication: Saudi Arabia NLM ID: 7909441 Publication Model: Print Cited Medium: Internet ISSN: 0379-5284 (Print) Linking ISSN: 03795284 NLM ISO Abbreviation: Saudi Med J Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Riyadh : Medical Services Department, Saudi Arabian Armed Forces, Ministry Of Defence And Aviation Original Publication: Riyadh, Saudi Arabia, Riyadh Al-Kharj Hospital Programme. |
| مواضيع طبية MeSH: | Down Syndrome/*complications , Heart Defects, Congenital/*complications, Child ; Child, Preschool ; Female ; Humans ; Infant ; Male ; Saudi Arabia |
| مستخلص: | Objectives: To to define the frequency and patterns of congenital heart disease (CHD) among children with Down syndrome (DS) in Northwest Saudi Arabia. Methods: We included children with confirmed DS referred to the regional pediatric cardiology unit in Madinah Maternity and Children Hospital between January 2008 and December 2013. Children were identified from the unit's data-base and the charts were reviewed retrospectively. We excluded term and preterm children with patent ducts arteriosus (PDA) and persistent foramen oval spontaneously resolved during the first 4 weeks of life. Results: A total of 302 children with DS were identified (50.3% male). Of these, 177 (58.6%) had CHD. Atrioventricular septal defect (AVSD) was the most frequent lesion identified in 72/177 (40.7%) followed by mixed left to right shunt defects (14.7%) and secundum atrial septal defect (ASD) (11.8%). Ventricular septal defect was detected in 10.7% and 8.5% had PDA beyond the neonatal period. There was no gender difference in the frequency of CHD (p=0.9) and the presence of CHD was not related to the genetic cause of DS (p=0.9). Conclusion: The frequency of CHD in our DS cohort is comparable with Europe, Asia ,and other KSA regions. However its pattern appears to be different from some areas in KSA. |
| التعليقات: | Comment on: Saudi Med J. 2016 Nov;37(11):1294-1295. (PMID: 27761573) |
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| تواريخ الأحداث: | Date Created: 20160707 Date Completed: 20170810 Latest Revision: 20181113 |
| رمز التحديث: | 20221213 |
| مُعرف محوري في PubMed: | PMC5018641 |
| DOI: | 10.15537/smj.2016.7.14536 |
| PMID: | 27381537 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0379-5284 |
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| DOI: | 10.15537/smj.2016.7.14536 |