دورية أكاديمية
Seropositivity of Toxoplasma gondii and Toxocara spp. in Children with Cryptogenic Epilepsy, Benha, Egypt.
العنوان: | Seropositivity of Toxoplasma gondii and Toxocara spp. in Children with Cryptogenic Epilepsy, Benha, Egypt. |
---|---|
المؤلفون: | Eraky MA; Parasitology Department, Faculty of Medicine, Benha University, Benha 13518, Egypt., Abdel-Hady S; Pediatrics Department, Faculty of Medicine, Benha University, Benha 13518, Egypt., Abdallah KF; Medical Parasitology Department, College of Medicine, Taif University, K.S.A. |
المصدر: | The Korean journal of parasitology [Korean J Parasitol] 2016 Jun; Vol. 54 (3), pp. 335-8. Date of Electronic Publication: 2016 Jun 30. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: The Korean Society for Parasitology and Tropical Medicine Country of Publication: Korea (South) NLM ID: 9435800 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1738-0006 (Electronic) Linking ISSN: 00234001 NLM ISO Abbreviation: Korean J Parasitol Subsets: MEDLINE |
أسماء مطبوعة: | Publication: 2015-2022: Sŏul : The Korean Society for Parasitology and Tropical Medicine Original Publication: Seoul, Korea : Korean Society for Parasitology, c1993-2022. |
مواضيع طبية MeSH: | Epilepsy/*complications , Toxascariasis/*epidemiology , Toxocara/*immunology , Toxoplasma/*immunology , Toxoplasmosis/*epidemiology, Adolescent ; Animals ; Antibodies, Helminth/blood ; Antibodies, Protozoan/blood ; Child ; Child, Preschool ; Egypt/epidemiology ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Immunoglobulin G/blood ; Infant ; Male ; Seroepidemiologic Studies ; Toxascariasis/immunology ; Toxoplasmosis/immunology |
مستخلص: | The present study aimed to investigate the possible association of Toxoplasma gondii and Toxocara spp. infections with cryptogenic epilepsy in children. The study was carried out between June 2014 and March 2015. Total 90 children (40 with cryptogenic epilepsy, 30 with non-cryptogenic epilepsy, and 20 healthy control children) were evaluated to determine the anti-Toxocara and anti-T. gondii IgG seropositivity using ELISA kits. Epileptic cases were selected from those attending the pediatrics outpatient clinic of Benha University Hospital, Pediatrics Neurology Unit, and from Benha Specialized Hospital of children. The results showed that the level of anti-T. gondii IgG seropositivity was significantly higher among children with cryptogenic epilepsy (20%) than among children with non-cryptogenic children (0%). In healthy controls (10%), there was no association between toxocariasis seropositivity and cryptogenic epilepsy (only 5.7%; 4 out of 70 cases) among cases and 10% (2 out of 20) among controls. Among toxocariasis IgG positive cases, 3 (7.5%) were cryptogenic, and only 1 (3.3%) was non-cryptogenic. These statistically significant results support the association between T. gondii infection and cryptogenic epilepsy while deny this association with toxocariasis. |
References: | J Pediatr. 1979 Jan;94(1):75-8. (PMID: 758428) Neurology. 2002 Apr 23;58(8):1256-61. (PMID: 11971095) Lancet Neurol. 2008 Jan;7(1):21-2. (PMID: 18068521) Epilepsia. 2005 Apr;46(4):470-2. (PMID: 15816939) Epilepsia. 2012 Jun;53(6):1095-103. (PMID: 22578079) Eur J Neurol. 2005 Apr;12(4):245-53. (PMID: 15804240) N Engl J Med. 2003 Sep 25;349(13):1257-66. (PMID: 14507951) Epilepsy Res. 2012 Nov;102(1-2):100-8. (PMID: 22749918) Br Med J. 1966 Jun 25;1(5503):1576-9. (PMID: 5949491) PLoS Negl Trop Dis. 2013;7(3):e2147. (PMID: 23556028) Epilepsia. 2014 Apr;55(4):475-82. (PMID: 24730690) Am J Trop Med Hyg. 1987 May;36(3):517-22. (PMID: 3578650) Seizure. 2007 Apr;16(3):233-7. (PMID: 17239629) Epilepsia. 1990 Jan-Feb;31(1):33-6. (PMID: 2303010) Epilepsia. 2011 Aug;52(8):1376-81. (PMID: 21627649) Epilepsia. 2011 Sep;52 Suppl 7:2-26. (PMID: 21899536) Epilepsia. 1975 Mar;16(1):1-66. (PMID: 804401) Epilepsia. 2008 Apr;49(4):594-9. (PMID: 18031545) Epilepsia. 2007 May;48(5):894-9. (PMID: 17508999) Epilepsia. 2001 Mar;42(3):436-8. (PMID: 11442166) |
فهرسة مساهمة: | Keywords: Egypt; Toxocara; Toxoplasma; child; cryptogenic epilepsy; seropositivity |
المشرفين على المادة: | 0 (Antibodies, Helminth) 0 (Antibodies, Protozoan) 0 (Immunoglobulin G) |
تواريخ الأحداث: | Date Created: 20160716 Date Completed: 20170404 Latest Revision: 20220330 |
رمز التحديث: | 20240628 |
مُعرف محوري في PubMed: | PMC4977784 |
DOI: | 10.3347/kjp.2016.54.3.335 |
PMID: | 27417090 |
قاعدة البيانات: | MEDLINE |
كن أول من يترك تعليقا!