دورية أكاديمية
Outbreak of H5N2 highly pathogenic avian Influenza A virus infection in two commercial layer facilities: lesions and viral antigen distribution.
| العنوان: | Outbreak of H5N2 highly pathogenic avian Influenza A virus infection in two commercial layer facilities: lesions and viral antigen distribution. |
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| المؤلفون: | Arruda PH; Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA (Arruda, Stevenson, Burrough, Gauger, Harmon, Magstadt, Yoon, Zhang, Madson, Piñeyro, Derscheid, Schwartz, Cooper, Halbur, Main, Sato, Arruda)U.S. Department of Agriculture, Animal and Plant Health Inspection Service, Veterinary Services, National Veterinary Services Laboratories, Ames, IA (Killian) paulohea@iastate.edu., Stevenson GW; Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA (Arruda, Stevenson, Burrough, Gauger, Harmon, Magstadt, Yoon, Zhang, Madson, Piñeyro, Derscheid, Schwartz, Cooper, Halbur, Main, Sato, Arruda)U.S. Department of Agriculture, Animal and Plant Health Inspection Service, Veterinary Services, National Veterinary Services Laboratories, Ames, IA (Killian)., Killian ML; Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA (Arruda, Stevenson, Burrough, Gauger, Harmon, Magstadt, Yoon, Zhang, Madson, Piñeyro, Derscheid, Schwartz, Cooper, Halbur, Main, Sato, Arruda)U.S. Department of Agriculture, Animal and Plant Health Inspection Service, Veterinary Services, National Veterinary Services Laboratories, Ames, IA (Killian)., Burrough ER; Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA (Arruda, Stevenson, Burrough, Gauger, Harmon, Magstadt, Yoon, Zhang, Madson, Piñeyro, Derscheid, Schwartz, Cooper, Halbur, Main, Sato, Arruda)U.S. Department of Agriculture, Animal and Plant Health Inspection Service, Veterinary Services, National Veterinary Services Laboratories, Ames, IA (Killian)., Gauger PC; Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA (Arruda, Stevenson, Burrough, Gauger, Harmon, Magstadt, Yoon, Zhang, Madson, Piñeyro, Derscheid, Schwartz, Cooper, Halbur, Main, Sato, Arruda)U.S. Department of Agriculture, Animal and Plant Health Inspection Service, Veterinary Services, National Veterinary Services Laboratories, Ames, IA (Killian)., Harmon KM; Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA (Arruda, Stevenson, Burrough, Gauger, Harmon, Magstadt, Yoon, Zhang, Madson, Piñeyro, Derscheid, Schwartz, Cooper, Halbur, Main, Sato, Arruda)U.S. Department of Agriculture, Animal and Plant Health Inspection Service, Veterinary Services, National Veterinary Services Laboratories, Ames, IA (Killian)., Magstadt DR; Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA (Arruda, Stevenson, Burrough, Gauger, Harmon, Magstadt, Yoon, Zhang, Madson, Piñeyro, Derscheid, Schwartz, Cooper, Halbur, Main, Sato, Arruda)U.S. Department of Agriculture, Animal and Plant Health Inspection Service, Veterinary Services, National Veterinary Services Laboratories, Ames, IA (Killian)., Yoon KJ; Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA (Arruda, Stevenson, Burrough, Gauger, Harmon, Magstadt, Yoon, Zhang, Madson, Piñeyro, Derscheid, Schwartz, Cooper, Halbur, Main, Sato, Arruda)U.S. Department of Agriculture, Animal and Plant Health Inspection Service, Veterinary Services, National Veterinary Services Laboratories, Ames, IA (Killian)., Zhang J; Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA (Arruda, Stevenson, Burrough, Gauger, Harmon, Magstadt, Yoon, Zhang, Madson, Piñeyro, Derscheid, Schwartz, Cooper, Halbur, Main, Sato, Arruda)U.S. Department of Agriculture, Animal and Plant Health Inspection Service, Veterinary Services, National Veterinary Services Laboratories, Ames, IA (Killian)., Madson DM; Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA (Arruda, Stevenson, Burrough, Gauger, Harmon, Magstadt, Yoon, Zhang, Madson, Piñeyro, Derscheid, Schwartz, Cooper, Halbur, Main, Sato, Arruda)U.S. Department of Agriculture, Animal and Plant Health Inspection Service, Veterinary Services, National Veterinary Services Laboratories, Ames, IA (Killian)., Piñeyro P; Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA (Arruda, Stevenson, Burrough, Gauger, Harmon, Magstadt, Yoon, Zhang, Madson, Piñeyro, Derscheid, Schwartz, Cooper, Halbur, Main, Sato, Arruda)U.S. Department of Agriculture, Animal and Plant Health Inspection Service, Veterinary Services, National Veterinary Services Laboratories, Ames, IA (Killian)., Derscheid RJ; Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA (Arruda, Stevenson, Burrough, Gauger, Harmon, Magstadt, Yoon, Zhang, Madson, Piñeyro, Derscheid, Schwartz, Cooper, Halbur, Main, Sato, Arruda)U.S. Department of Agriculture, Animal and Plant Health Inspection Service, Veterinary Services, National Veterinary Services Laboratories, Ames, IA (Killian)., Schwartz KJ; Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA (Arruda, Stevenson, Burrough, Gauger, Harmon, Magstadt, Yoon, Zhang, Madson, Piñeyro, Derscheid, Schwartz, Cooper, Halbur, Main, Sato, Arruda)U.S. Department of Agriculture, Animal and Plant Health Inspection Service, Veterinary Services, National Veterinary Services Laboratories, Ames, IA (Killian)., Cooper VL; Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA (Arruda, Stevenson, Burrough, Gauger, Harmon, Magstadt, Yoon, Zhang, Madson, Piñeyro, Derscheid, Schwartz, Cooper, Halbur, Main, Sato, Arruda)U.S. Department of Agriculture, Animal and Plant Health Inspection Service, Veterinary Services, National Veterinary Services Laboratories, Ames, IA (Killian)., Halbur PG; Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA (Arruda, Stevenson, Burrough, Gauger, Harmon, Magstadt, Yoon, Zhang, Madson, Piñeyro, Derscheid, Schwartz, Cooper, Halbur, Main, Sato, Arruda)U.S. Department of Agriculture, Animal and Plant Health Inspection Service, Veterinary Services, National Veterinary Services Laboratories, Ames, IA (Killian)., Main RG; Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA (Arruda, Stevenson, Burrough, Gauger, Harmon, Magstadt, Yoon, Zhang, Madson, Piñeyro, Derscheid, Schwartz, Cooper, Halbur, Main, Sato, Arruda)U.S. Department of Agriculture, Animal and Plant Health Inspection Service, Veterinary Services, National Veterinary Services Laboratories, Ames, IA (Killian)., Sato Y; Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA (Arruda, Stevenson, Burrough, Gauger, Harmon, Magstadt, Yoon, Zhang, Madson, Piñeyro, Derscheid, Schwartz, Cooper, Halbur, Main, Sato, Arruda)U.S. Department of Agriculture, Animal and Plant Health Inspection Service, Veterinary Services, National Veterinary Services Laboratories, Ames, IA (Killian)., Arruda BL; Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA (Arruda, Stevenson, Burrough, Gauger, Harmon, Magstadt, Yoon, Zhang, Madson, Piñeyro, Derscheid, Schwartz, Cooper, Halbur, Main, Sato, Arruda)U.S. Department of Agriculture, Animal and Plant Health Inspection Service, Veterinary Services, National Veterinary Services Laboratories, Ames, IA (Killian). |
| المصدر: | Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc [J Vet Diagn Invest] 2016 Sep; Vol. 28 (5), pp. 568-73. Date of Electronic Publication: 2016 Jul 16. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Sage Country of Publication: United States NLM ID: 9011490 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1943-4936 (Electronic) Linking ISSN: 10406387 NLM ISO Abbreviation: J Vet Diagn Invest Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2011-: Thousand Oaks, CA : Sage Original Publication: 1989-2004 : Columbia, MO : American Association of Veterinary Laboratory Diagnosticians |
| مواضيع طبية MeSH: | Influenza A Virus, H5N2 Subtype/*isolation & purification , Influenza in Birds/*epidemiology, Animals ; Antigens, Viral/blood ; Chickens ; Disease Outbreaks/veterinary ; Influenza A Virus, H5N2 Subtype/genetics ; Influenza A Virus, H5N2 Subtype/immunology ; Influenza in Birds/pathology ; Influenza in Birds/virology ; Iowa/epidemiology ; Liver/pathology ; Phylogeny ; Real-Time Polymerase Chain Reaction/veterinary |
| مستخلص: | The largest outbreak of highly pathogenic avian Influenza A virus (HPAIV) infection in U.S. history began in December 2014 resulting in the euthanasia of millions of birds and collateral economic consequences to the U.S. poultry industry. We describe 2 cases of H5N2 HPAIV infection in laying hens in Iowa. Following a sharp increase in mortality with minimal clinical signs, 15 dead birds, from 2 unrelated farms, were submitted to the Iowa State University Veterinary Diagnostic Laboratory. Common lesions included diffuse edema and multifocal hemorrhage of the comb, catarrhal exudate in the oropharynx, and multifocal tracheal hemorrhage. Less common lesions included epicardial petechiae, splenic hemorrhage, and pancreatic necrosis. Influenza A virus nucleoprotein was detected by immunohistochemistry in multiple cell types including ependymal cells, the choroid plexus, neurons, respiratory epithelium and macrophages in the lung, cardiac myocytes, endothelial cells, necrotic foci in the spleen, Kupffer cells in the liver, and necrotic acinar cells in the pancreas. Real-time polymerase chain reaction and sequencing confirmed H5N2 HPAIV with molecular characteristics similar to other contemporary U.S. H5N2 HPAIVs in both cases. (© 2016 The Author(s).) |
| فهرسة مساهمة: | Keywords: Avian influenza; H5N2; highly pathogenic avian influenza; layers; natural infection |
| المشرفين على المادة: | 0 (Antigens, Viral) |
| تواريخ الأحداث: | Date Created: 20160718 Date Completed: 20170424 Latest Revision: 20220311 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1177/1040638716658929 |
| PMID: | 27423731 |
| قاعدة البيانات: | MEDLINE |
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