دورية أكاديمية
The Non-Dialysis Chronic Renal Insufficiency study (ND-CRIS): an open prospective hospital-based cohort study in France.
| العنوان: | The Non-Dialysis Chronic Renal Insufficiency study (ND-CRIS): an open prospective hospital-based cohort study in France. |
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| المؤلفون: | Massol J; Institut PHISQUARE, 20, rue Saint Saëns, 75015, Paris, France. jmassol@phisquare.org., Janin G; Centre Hospitalier de Mâcon, 350, boulevard Escande, 71018, Mâcon Cedex, France., Bachot C; Institut PHISQUARE, 20, rue Saint Saëns, 75015, Paris, France., Gousset C; Institut PHISQUARE, 20, rue Saint Saëns, 75015, Paris, France., Sainte-Claire Deville G; Institut PHISQUARE, 20, rue Saint Saëns, 75015, Paris, France., Chalopin JM; Department of Nephrology, CHRU de Besançon, Hôpital Jean Minjoz, 3, boulevard Alexandre Fleming, 25030, Besançon, France. |
| المصدر: | BMC nephrology [BMC Nephrol] 2016 Jul 22; Vol. 17 (1), pp. 92. Date of Electronic Publication: 2016 Jul 22. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: BioMed Central Country of Publication: England NLM ID: 100967793 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2369 (Electronic) Linking ISSN: 14712369 NLM ISO Abbreviation: BMC Nephrol Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: London : BioMed Central, [2000- |
| مواضيع طبية MeSH: | Quality of Health Care*, Renal Insufficiency, Chronic/*epidemiology , Renal Insufficiency, Chronic/*physiopathology, Adult ; Aged ; Aged, 80 and over ; Disease Progression ; France/epidemiology ; Glomerular Filtration Rate ; Humans ; Incidence ; Middle Aged ; Pharmacoepidemiology ; Prospective Studies ; Renal Insufficiency, Chronic/therapy ; Research Design ; Young Adult |
| مستخلص: | Background: Chronic kidney disease (CKD) amounts to a heavy burden for health services. There is no long-running epidemiological tool for CKD before dialysis. We here present the protocol for a cohort of patients with "non-dialysis" CKD receiving care in the Bourgogne-Franche-Comté region of France. The aim of this cohort was to periodically describe the characteristics of patients included and their care provision, to analyse evolution in care and patients' kidney function outcomes. Methods: The ND-CRIS cohort is prevalent and incident. Patients are included in the cohort if over 18, with a glomerula filtration rate (GFR) <60 ml/min/1.73 m2, non-dialysed, informed on the research and not having opposed it, and followed by a nephrologist in one of the 9 centres in the region, (3 pilot centres joined by 6 others in 2015). All the patients are followed up, with varying time lapses according to the degree of GFR deterioration. Data is collected by clinical research assistants (CRAs) using a dedicated computerised case-report form (CRF). Professional practices are assessed using indicators defined by the French Health Authority. The follow-up of patients included should enable assessment of the evolution of their GFR and co-morbidities. The periodic descriptions should give insight into evolution in epidemiological terms. Discussion: The ND-CRIS meets a need in epidemiological tools in France for CKD. The cohort does claim to be representative, of ND-CKD patients receiving care from nephrologists. The open and incident nature of the cohort and the number of patients included in the ND-CRIS should provide answers to questions that cannot be answered by smaller solely prevalent cohorts. The numbers of patients included over the study period (2391 patients in 3 centres in 3 years) suggests that the figure of 5000 patients should be reached by 2017. The participation of nephrologists and the rate of inclusions point to the feasibility of the implementation of this cohort. Beyond the information to be found in the CRFs, this cohort should also enable ad hoc studies, in particular in the area of pharmaco-epidemiology, and it could later serve as a research platform and as a public health surveillance tool. |
| References: | Am J Kidney Dis. 2003 Jan;41(1):1-12. (PMID: 12500213) PLoS One. 2014 Dec 11;9(12):e114839. (PMID: 25503256) Med Sci (Paris). 2009 Jan;25(1):93-7. (PMID: 19154701) JAMA. 2012 May 9;307(18):1941-51. (PMID: 22570462) Int J Nephrol Renovasc Dis. 2012;5:151-63. (PMID: 23293534) Am J Kidney Dis. 2002 Feb;39(2 Suppl 1):S1-266. (PMID: 11904577) Nephrol Dial Transplant. 2014 Aug;29(8):1500-7. (PMID: 24064325) Nephrol Ther. 2009 Jun;5 Suppl 4:S250-5. (PMID: 19596344) Nephrol Dial Transplant. 2006 Feb;21(2):411-8. (PMID: 16234286) |
| فهرسة مساهمة: | Keywords: Chronic renal disease; Cohort; Epidemiology; Pharmacoepidemiology; Renal insufficiency |
| تواريخ الأحداث: | Date Created: 20160725 Date Completed: 20171116 Latest Revision: 20240325 |
| رمز التحديث: | 20240325 |
| مُعرف محوري في PubMed: | PMC4957911 |
| DOI: | 10.1186/s12882-016-0307-6 |
| PMID: | 27448596 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1471-2369 |
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| DOI: | 10.1186/s12882-016-0307-6 |