دورية أكاديمية

Genome-Wide Association Mapping of Fusarium Head Blight Resistance in Wheat using Genotyping-by-Sequencing.

التفاصيل البيبلوغرافية
العنوان: Genome-Wide Association Mapping of Fusarium Head Blight Resistance in Wheat using Genotyping-by-Sequencing.
المؤلفون: Arruda MP, Brown P, Brown-Guedira G, Krill AM, Thurber C, Merrill KR, Foresman BJ, Kolb FL
المصدر: The plant genome [Plant Genome] 2016 Mar; Vol. 9 (1).
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
اللغة: English
بيانات الدورية: Publisher: Crop Science Society of America Country of Publication: United States NLM ID: 101273919 Publication Model: Print Cited Medium: Internet ISSN: 1940-3372 (Electronic) Linking ISSN: 19403372 NLM ISO Abbreviation: Plant Genome Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Madison, WI : Crop Science Society of America
مواضيع طبية MeSH: Genome-Wide Association Study* , Genotyping Techniques*, Disease Resistance/*genetics , Fusarium/*physiology , Triticum/*genetics , Triticum/*microbiology, Genotype ; Plant Diseases/genetics ; Quantitative Trait Loci
مستخلص: Fusarium head blight (FHB) is one of the most important wheat ( L.) diseases worldwide, and host resistance displays complex genetic control. A genome-wide association study (GWAS) was performed on 273 winter wheat breeding lines from the midwestern and eastern regions of the United States to identify chromosomal regions associated with FHB resistance. Genotyping-by-sequencing (GBS) was used to identify 19,992 single-nucleotide polymorphisms (SNPs) covering all 21 wheat chromosomes. Marker-trait associations were performed with different statistical models, the most appropriate being a compressed mixed linear model (cMLM) controlling for relatedness and population structure. Ten significant SNP-trait associations were detected on chromosomes 4A, 6A, 7A, 1D, 4D, and 7D, and multiple SNPs were associated with on chromosome 3B. Although combination of favorable alleles of these SNPs resulted in lower levels of severity (SEV), incidence (INC), and deoxynivalenol concentration (DON), lines carrying multiple beneficial alleles were in very low frequency for most traits. These SNPs can now be used for creating new breeding lines with different combinations of favorable alleles. This is one of the first GWAS using genomic resources from the International Wheat Genome Sequencing Consortium (IWGSC).
(Copyright © 2016 Crop Science Society of America.)
تواريخ الأحداث: Date Created: 20161130 Date Completed: 20180821 Latest Revision: 20220409
رمز التحديث: 20231215
DOI: 10.3835/plantgenome2015.04.0028
PMID: 27898754
قاعدة البيانات: MEDLINE