دورية أكاديمية
Interaction of chitin/chitosan with salivary and other epithelial cells-An overview.
| العنوان: | Interaction of chitin/chitosan with salivary and other epithelial cells-An overview. |
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| المؤلفون: | Patil SV; Centre for Nanosciences and Molecular Medicine, Amrita University, Kochi, Kerala 682041, India., Nanduri LSY; Centre for Nanosciences and Molecular Medicine, Amrita University, Kochi, Kerala 682041, India. Electronic address: nlalitha21643@aims.amrita.edu. |
| المصدر: | International journal of biological macromolecules [Int J Biol Macromol] 2017 Nov; Vol. 104 (Pt B), pp. 1398-1406. Date of Electronic Publication: 2017 Mar 15. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Amsterdam : Elsevier Original Publication: Guildford, Eng., IPC Science and Technology Press. |
| مواضيع طبية MeSH: | Chitin/*pharmacology , Chitosan/*pharmacology , Epithelial Cells/*drug effects , Salivary Glands/*drug effects, Animals ; Humans ; Tissue Engineering |
| مستخلص: | Chitin and its deacetylated form, chitosan, have been widely used for tissue engineering of both epithelial and mesenchymal tissues. Epithelial cells characterised by their sheet-like tight cellular arrangement and polarised nature, constitute a major component in various organs and play a variety of roles including protection, secretion and maintenance of tissue homeostasis. Regeneration of damaged epithelial tissues has been studied using biomaterials such as chitin, chitosan, hyaluronan, gelatin and alginate. Chitin and chitosan are known to promote proliferation of various embryonic and adult epithelial cells. However it is not clearly understood how this activity is achieved or what are the mechanisms involved in the chitin/chitosan driven proliferation of epithelial cells. Mechanistic understanding of influence of chitin/chitosan on epithelial cells will guide us to develop more targeted regenerative scaffold/hydrogel systems. Therefore, current review attempts to elicit a mechanistic insight into how chitin and chitosan interact with salivary, mammary, skin, nasal, lung, intestinal and bladder epithelial cells. (Copyright © 2017 Elsevier B.V. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Chitin/Chitosan; Epithelial cells; Salivary gland |
| المشرفين على المادة: | 1398-61-4 (Chitin) 9012-76-4 (Chitosan) |
| تواريخ الأحداث: | Date Created: 20170319 Date Completed: 20180504 Latest Revision: 20180504 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1016/j.ijbiomac.2017.03.058 |
| PMID: | 28315439 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1879-0003 |
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| DOI: | 10.1016/j.ijbiomac.2017.03.058 |