دورية أكاديمية
Emerging Mechanisms and Roles for Asymmetric Cytokinesis.
| العنوان: | Emerging Mechanisms and Roles for Asymmetric Cytokinesis. |
|---|---|
| المؤلفون: | Thieleke-Matos C; i3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal; Cell Division and Genomic stability, IBMC, Instituto de Biologia Molecular e Celular, and i3S, Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal., Osório DS; i3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal; Cytoskeletal Dynamics, IBMC, Instituto de Biologia Molecular e Celular, and i3S, Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal., Carvalho AX; i3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal; Cytoskeletal Dynamics, IBMC, Instituto de Biologia Molecular e Celular, and i3S, Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal., Morais-de-Sá E; i3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal; Cell Division and Genomic stability, IBMC, Instituto de Biologia Molecular e Celular, and i3S, Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal. Electronic address: eurico.sa@ibmc.up.pt. |
| المصدر: | International review of cell and molecular biology [Int Rev Cell Mol Biol] 2017; Vol. 332, pp. 297-345. Date of Electronic Publication: 2017 Mar 07. |
| نوع المنشور: | Journal Article; Review; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101475846 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-6448 (Print) Linking ISSN: 19376448 NLM ISO Abbreviation: Int Rev Cell Mol Biol Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Amsterdam : Elsevier |
| مواضيع طبية MeSH: | Asymmetric Cell Division* , Cytokinesis*, Animals ; Body Patterning ; Cell Shape ; Humans ; Models, Biological |
| مستخلص: | Cytokinesis completes cell division by physically separating the contents of the mother cell between the two daughter cells. This event requires the highly coordinated reorganization of the cytoskeleton within a precise window of time to ensure faithful genomic segregation. In addition, recent progress in the field highlighted the importance of cytokinesis in providing particularly important cues in the context of multicellular tissues. The organization of the cytokinetic machinery and the asymmetric localization or inheritance of the midbody remnants is critical to define the spatial distribution of mechanical and biochemical signals. After a brief overview of the conserved steps of animal cytokinesis, we review the mechanisms controlling polarized cytokinesis focusing on the challenges of epithelial cytokinesis. Finally, we discuss the significance of these asymmetries in defining embryonic body axes, determining cell fate, and ensuring the correct propagation of epithelial organization during proliferation. (© 2017 Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Actomyosin; Adherens junction; C. elegans; Cell fate; Contractile ring; Cytokinesis; Drosophila; Epithelial tissue; Midbody; Multicellularity |
| تواريخ الأحداث: | Date Created: 20170521 Date Completed: 20180223 Latest Revision: 20180315 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1016/bs.ircmb.2017.01.004 |
| PMID: | 28526136 |
| قاعدة البيانات: | MEDLINE |
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