دورية أكاديمية
Recent advances and clinical insights into the use of proteomics in the study of atherosclerosis.
| العنوان: | Recent advances and clinical insights into the use of proteomics in the study of atherosclerosis. |
|---|---|
| المؤلفون: | Mourino-Alvarez L; a Department of Vascular Physiopathology , Hospital Nacional de Paraplejicos , Toledo , Spain., Baldan-Martin M; a Department of Vascular Physiopathology , Hospital Nacional de Paraplejicos , Toledo , Spain., Rincon R; a Department of Vascular Physiopathology , Hospital Nacional de Paraplejicos , Toledo , Spain., Martin-Rojas T; a Department of Vascular Physiopathology , Hospital Nacional de Paraplejicos , Toledo , Spain., Corbacho-Alonso N; a Department of Vascular Physiopathology , Hospital Nacional de Paraplejicos , Toledo , Spain., Sastre-Oliva T; a Department of Vascular Physiopathology , Hospital Nacional de Paraplejicos , Toledo , Spain., Barderas MG; a Department of Vascular Physiopathology , Hospital Nacional de Paraplejicos , Toledo , Spain. |
| المصدر: | Expert review of proteomics [Expert Rev Proteomics] 2017 Aug; Vol. 14 (8), pp. 701-713. Date of Electronic Publication: 2017 Jul 14. |
| نوع المنشور: | Journal Article; Review; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Informa Healthcare Country of Publication: England NLM ID: 101223548 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-8387 (Electronic) Linking ISSN: 14789450 NLM ISO Abbreviation: Expert Rev Proteomics Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: June 2013- : London : Informa Healthcare Original Publication: London : Future Drugs Ltd., [2004]- |
| مواضيع طبية MeSH: | Atherosclerosis/*diagnosis , Proteomics/*methods, Atherosclerosis/etiology ; Humans ; Models, Biological ; Protein Interaction Mapping ; Protein Processing, Post-Translational ; Risk Factors |
| مستخلص: | Introduction: The application of new proteomics methods may help to identify new diagnostic/predictive molecular markers in an attempt to improve the clinical management of atherosclerosis. Areas covered: Technological advances in proteomics have enhanced its sensitivity and multiplexing capacity, as well as the possibility of studying protein interactions and tissue structure. These advances will help us better understand the molecular mechanisms at play in atherosclerosis as a biological system. Moreover, this should help identify new predictive/diagnostic biomarkers and therapeutic targets that may facilitate effective risk stratification and early diagnosis, with the ensuing rapid implementation of treatment. This review provides a comprehensive overview of the novel methods in proteomics, including state-of-the-art techniques, novel biological samples and applications for the study of atherosclerosis. Expert commentary: Collaboration between clinicians and researchers is crucial to further validate and introduce new molecular markers to manage atherosclerosis that are identified using the most up to date proteomic approaches. |
| فهرسة مساهمة: | Keywords: Artery; atheroma; atherosclerosis; cardiovascular diseases; lipoproteins; mass spectrometry; proteomics |
| تواريخ الأحداث: | Date Created: 20170711 Date Completed: 20180423 Latest Revision: 20180430 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1080/14789450.2017.1353912 |
| PMID: | 28689450 |
| قاعدة البيانات: | MEDLINE |
PDF full text from Publisher | تدمد: | 1744-8387 |
|---|---|
| DOI: | 10.1080/14789450.2017.1353912 |