دورية أكاديمية
A Case of Type 1 Autoimmune Pancreatitis (AIP), a Form of IgG4-Related Disease (IgG4-RD).
| العنوان: | A Case of Type 1 Autoimmune Pancreatitis (AIP), a Form of IgG4-Related Disease (IgG4-RD). |
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| المؤلفون: | El Euch M; Department of Internal Medicine 'A', Charles Nicolle Hospital, Tunis, Tunisia.; University of Tunis Manar, Tunis, Tunisia., Hddad S; Department of Internal Medicine 'A', Charles Nicolle Hospital, Tunis, Tunisia.; University of Tunis Manar, Tunis, Tunisia., Mahfoudhi M; Department of Internal Medicine 'A', Charles Nicolle Hospital, Tunis, Tunisia.; University of Tunis Manar, Tunis, Tunisia.; Research Laboratory of Kidney Diseases (LR00SP01), Charles Nicolle Hospital, Tunis, Tunisia., Maktouf H; Department of Internal Medicine 'A', Charles Nicolle Hospital, Tunis, Tunisia.; University of Tunis Manar, Tunis, Tunisia., Ben Hamida F; Department of Internal Medicine 'A', Charles Nicolle Hospital, Tunis, Tunisia.; University of Tunis Manar, Tunis, Tunisia.; Research Laboratory of Kidney Diseases (LR00SP01), Charles Nicolle Hospital, Tunis, Tunisia., Jaziri F; Department of Internal Medicine 'A', Charles Nicolle Hospital, Tunis, Tunisia.; University of Tunis Manar, Tunis, Tunisia., Ben Abdelghani K; Department of Internal Medicine 'A', Charles Nicolle Hospital, Tunis, Tunisia.; University of Tunis Manar, Tunis, Tunisia., Turki S; Department of Internal Medicine 'A', Charles Nicolle Hospital, Tunis, Tunisia.; University of Tunis Manar, Tunis, Tunisia., Ben Abdallah T; Department of Internal Medicine 'A', Charles Nicolle Hospital, Tunis, Tunisia.; University of Tunis Manar, Tunis, Tunisia.; Research Laboratory of Kidney Diseases (LR00SP01), Charles Nicolle Hospital, Tunis, Tunisia. |
| المصدر: | The American journal of case reports [Am J Case Rep] 2017 Jul 24; Vol. 18, pp. 822-825. Date of Electronic Publication: 2017 Jul 24. |
| نوع المنشور: | Case Reports; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: International Scientific Information, Inc Country of Publication: United States NLM ID: 101489566 Publication Model: Electronic Cited Medium: Internet ISSN: 1941-5923 (Electronic) Linking ISSN: 19415923 NLM ISO Abbreviation: Am J Case Rep Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2014- > : Smithtown, NY : International Scientific Information, Inc. Original Publication: Albertson, NY : International Scientific Literature, Inc. |
| مواضيع طبية MeSH: | Autoimmune Diseases/*diagnosis , Immunoglobulin G/*blood , Pancreatitis, Chronic/*diagnosis , Pancreatitis, Chronic/*immunology, Aged ; Autoimmune Diseases/immunology ; Biomarkers/blood ; Humans ; Male ; Pancreas/diagnostic imaging |
| مستخلص: | BACKGROUND Type 1 autoimmune pancreatitis (AIP), also known as lymphoplasmacytic sclerosing pancreatitis (LPSP), is a rare cause of chronic pancreatitis, characterized by a fibro-inflammatory process. However, patients with AIP may have a good response to corticosteroid therapy. We describe a Tunisian patient with AIP that was confirmed to be an IgG4-related disease (IgG4-RD). CASE REPORT We describe a case of a 70-year-old man who was admitted to hospital for obstructive jaundice and abdominal pain. Serum liver function tests were abnormal and upper abdominal computed tomography (CT) imaging showed diffuse pancreatic swelling and strictures of the main pancreatic duct without any focal lesion. Pancreatico-biliary magnetic resonance imaging (MRI) showed a thickened rim surrounding the pancreatic duct Serum IgG4 levels were elevated, resulting in a diagnosis of IgG4-related AIP. The patient showed a good clinical, biochemical, and radiological response following steroid therapy in combination with azathioprine. CONCLUSIONS The diagnostic workup of IgG4-RD is complex and usually requires a combination of clinical examination, imaging, and serological analysis. As this case report has demonstrated, IgG4-RD should be considered in patients who present with pancreatitis or AIP, because of the favorable response to steroid therapy, particularly when treatment is initiated early. |
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| المشرفين على المادة: | 0 (Biomarkers) 0 (Immunoglobulin G) |
| تواريخ الأحداث: | Date Created: 20170725 Date Completed: 20171201 Latest Revision: 20231112 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC5539804 |
| DOI: | 10.12659/ajcr.904263 |
| PMID: | 28736430 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1941-5923 |
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| DOI: | 10.12659/ajcr.904263 |