دورية أكاديمية

Non-participation in systematic screening for osteoporosis-the ROSE trial.

التفاصيل البيبلوغرافية
العنوان: Non-participation in systematic screening for osteoporosis-the ROSE trial.
المؤلفون: Rothmann MJ; Department of Endocrinology, Odense University Hospital, Kloevervaenget 10, 6.sal, 5000, Odense C, Odense, Denmark. mette.rothmann@rsyd.dk.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark. mette.rothmann@rsyd.dk., Möller S; Odense Patient Data Explorative Network (OPEN), Department of Clinical Research, University of Southern Denmark and Odense University Hospital, Odense, Denmark., Holmberg T; Department of Health Promotion and Prevention, National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark., Højberg M; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Research, Hospital of Southern Norway, Kristiansand, Norway., Gram J; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Endocrinology, Hospital of Southwest Denmark, Esbjerg, Denmark., Bech M; KORA, the Danish Institute for Local and Regional Government Research, Copenhagen, Denmark., Brixen K; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Odense University Hospital, Odense, Denmark., Hermann AP; Department of Endocrinology, Odense University Hospital, Kloevervaenget 10, 6.sal, 5000, Odense C, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark., Glüer CC; Section Biomedical Imaging, Department of Radiology and Neuroradiology, Christian-Albrechts-Universitäts zu Kiel, Kiel, Germany., Barkmann R; Section Biomedical Imaging, Department of Radiology and Neuroradiology, Christian-Albrechts-Universitäts zu Kiel, Kiel, Germany., Rubin KH; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Odense Patient Data Explorative Network (OPEN), Department of Clinical Research, University of Southern Denmark and Odense University Hospital, Odense, Denmark.
المصدر: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA [Osteoporos Int] 2017 Dec; Vol. 28 (12), pp. 3389-3399. Date of Electronic Publication: 2017 Sep 05.
نوع المنشور: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Springer International Country of Publication: England NLM ID: 9100105 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1433-2965 (Electronic) Linking ISSN: 0937941X NLM ISO Abbreviation: Osteoporos Int Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London, UK : Springer International, c1990-
مواضيع طبية MeSH: Mass Screening/*psychology , Osteoporosis, Postmenopausal/*diagnosis , Patient Acceptance of Health Care/*statistics & numerical data, Absorptiometry, Photon/methods ; Aged ; Aged, 80 and over ; Comorbidity ; Denmark ; Female ; Humans ; Mass Screening/methods ; Osteoporosis, Postmenopausal/psychology ; Osteoporotic Fractures/etiology ; Osteoporotic Fractures/prevention & control ; Osteoporotic Fractures/psychology ; Patient Acceptance of Health Care/psychology ; Patient Dropouts/psychology ; Patient Dropouts/statistics & numerical data ; Patient Participation ; Risk Assessment/methods ; Socioeconomic Factors ; Surveys and Questionnaires
مستخلص: Population-based screening for osteoporosis is still controversial and has not been implemented. Non-participation in systematic screening was evaluated in 34,229 women age 65-81 years. Although participation rate was high, non-participation was associated with comorbidity, aging other risk factors for fractures, and markers of low social status, e.g., low income, pension, and living alone. A range of strategies is needed to increase participation, including development of targeted information and further research to better understand the barriers and enablers in screening for osteoporosis.
Introduction: Participation is crucial to the success of a screening program. The objective of this study was to analyze non-participation in Risk-stratified Osteoporosis Strategy Evaluation, a two-step population-based screening program for osteoporosis.
Methods: Thirty-four thousand two hundred twenty-nine women aged 65 to 81 years were randomly selected from the background population and randomized to either a screening group (intervention) or a control group. All women received a self-administered questionnaire designed to allow calculation of future risk of fracture based on FRAX. In the intervention group, women with an estimated high risk of future fracture were invited to DXA scanning. Information on individual socioeconomic status and comorbidity was obtained from national registers.
Results: A completed questionnaire was returned by 20,905 (61%) women. Non-completion was associated with older age, living alone, lower education, lower income, and higher comorbidity. In the intervention group, ticking "not interested in DXA" in the questionnaire was associated with older age, living alone, and low self-perceived fracture risk. Women with previous fracture or history of parental hip fracture were more likely to accept screening by DXA. Dropping out when offered DXA, was associated with older age, current smoking, higher alcohol consumption, and physical impairment.
Conclusions: Barriers to population-based screening for osteoporosis appear to be both psychosocial and physical in nature. Women who decline are older, have lower self-perceived fracture risk, and more often live alone compared to women who accept the program. Dropping out after primary acceptance is associated not only with aging and physical impairment but also with current smoking and alcohol consumption. Measures to increase program participation could include targeted information and reducing physical barriers for attending screening procedures.
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فهرسة مساهمة: Keywords: Decline; Non-participation; Osteoporosis; Population-based screening; Women
سلسلة جزيئية: ClinicalTrials.gov NCT01388244
تواريخ الأحداث: Date Created: 20170907 Date Completed: 20180806 Latest Revision: 20181113
رمز التحديث: 20231215
DOI: 10.1007/s00198-017-4205-y
PMID: 28875257
قاعدة البيانات: MEDLINE
الوصف
تدمد:1433-2965
DOI:10.1007/s00198-017-4205-y