دورية أكاديمية
أعرض في EDS

Acute CD47 Blockade During Ischemic Myocardial Reperfusion Enhances Phagocytosis-Associated Cardiac Repair.

التفاصيل البيبلوغرافية
العنوان: Acute CD47 Blockade During Ischemic Myocardial Reperfusion Enhances Phagocytosis-Associated Cardiac Repair.
المؤلفون: Zhang S; Department of Pathology and Feinberg Cardiovascular Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, Illinois., Yeap XY; Department of Pathology and Feinberg Cardiovascular Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, Illinois., DeBerge M; Department of Pathology and Feinberg Cardiovascular Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, Illinois., Naresh NK; Department of Pathology and Feinberg Cardiovascular Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, Illinois., Wang K; Department of Pathology and Feinberg Cardiovascular Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, Illinois., Jiang Z; Department of Pathology and Feinberg Cardiovascular Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, Illinois., Wilcox JE; Department of Pathology and Feinberg Cardiovascular Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, Illinois., White SM; Department of Pathology and Feinberg Cardiovascular Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, Illinois., Morrow JP; Columbia University, New York, New York., Burridge PW; Department of Pharmacology and Center for Pharmacogenomics, Feinberg School of Medicine, Northwestern University, Chicago, Illinois., Procissi D; Department of Pathology and Feinberg Cardiovascular Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, Illinois., Scott EA; Department of Pathology and Feinberg Cardiovascular Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, Illinois., Frazier W; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri., Thorp EB; Department of Pathology and Feinberg Cardiovascular Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
المصدر: JACC. Basic to translational science [JACC Basic Transl Sci] 2017 Aug; Vol. 2 (4), pp. 386-397.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier on behalf of the American College of Cardiology Foundation Country of Publication: United States NLM ID: 101677259 Publication Model: Print Cited Medium: Print ISSN: 2452-302X (Print) Linking ISSN: 2452302X NLM ISO Abbreviation: JACC Basic Transl Sci Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: [New York] : Elsevier on behalf of the American College of Cardiology Foundation, [2016]-
مستخلص: Our data suggest that, after a myocardial infarction, integrin-associated protein CD47 on cardiac myocytes is elevated. In culture, increased CD47 on the surface of dying cardiomyocytes impairs phagocytic removal by immune cell macrophages. After myocardial ischemia and reperfusion, acute CD47 inhibition with blocking antibodies enhanced dead myocyte clearance by cardiac phagocytes and also improved the resolution of cardiac inflammation, reduced infarct size, and preserved cardiac contractile function. Early targeting of CD47 in the myocardium after reperfusion may be a new strategy to enhance wound repair in the ischemic heart.
References: Int J Cardiol. 2008 Nov 12;130(2):147-58. (PMID: 18656272)
Circ Res. 2009 Nov 20;105(11):1072-82. (PMID: 19834009)
J Am Coll Cardiol. 2008 Apr 8;51(14):1384-92. (PMID: 18387441)
Cell. 2009 Jul 23;138(2):271-85. (PMID: 19632178)
Matrix Biol. 2009 Mar;28(2):110-9. (PMID: 19284971)
Hypertension. 2014 Jan;63(1):96-104. (PMID: 24101669)
Circulation. 2016 Mar 1;133(9):826-39. (PMID: 26819373)
J Am Heart Assoc. 2014 Jun 10;3(3):e000670. (PMID: 24922625)
Nitric Oxide. 2009 Aug;21(1):52-62. (PMID: 19481167)
Circ Res. 2001 Aug 3;89(3):279-86. (PMID: 11485979)
Science. 2013 Jul 5;341(6141):88-91. (PMID: 23722425)
Methods Enzymol. 2011;489:277-96. (PMID: 21266236)
Cell. 2005 Oct 21;123(2):321-34. (PMID: 16239148)
Methods Mol Biol. 2013;1004:115-33. (PMID: 23733573)
Blood. 2012 Jun 7;119(23):5512-21. (PMID: 22427202)
Nature. 2016 Aug 4;536(7614):86-90. (PMID: 27437576)
J Exp Med. 2003 Mar 3;197(5):625-32. (PMID: 12615903)
J Biol Chem. 1997 Jun 6;272(23 ):14740-6. (PMID: 9169439)
Proc Natl Acad Sci U S A. 2007 Aug 21;104(34):13744-9. (PMID: 17699632)
Clin Exp Immunol. 2008 Jun;152(3):448-55. (PMID: 18422728)
Annu Rev Physiol. 2010;72:19-44. (PMID: 20148665)
Mol Biol Cell. 1998 Apr;9(4):865-74. (PMID: 9529384)
Matrix Biol. 2011 Mar;30(2):154-61. (PMID: 21256215)
J Cardiovasc Pharmacol. 2014 Mar;63(3):185-95. (PMID: 24072174)
Circ Res. 2013 Sep 27;113(8):1004-12. (PMID: 23836795)
Proc Natl Acad Sci U S A. 2005 Sep 13;102(37):13141-6. (PMID: 16150726)
J Am Coll Cardiol. 2010 Apr 13;55(15):1629-38. (PMID: 20378083)
J Biol Chem. 2002 Mar 22;277(12):10028-36. (PMID: 11792697)
Circulation. 2008 Nov 11;118(20):2019-21. (PMID: 19001032)
J Clin Invest. 2014 Mar;124(3):1083-97. (PMID: 24531546)
J Mol Cell Cardiol. 2015 Oct;87:171-9. (PMID: 26316303)
Circ Res. 2010 Aug 6;107(3):374-87. (PMID: 20558828)
Matrix Biol. 2014 Jul;37:25-34. (PMID: 24840925)
Chest. 2006 Jun;129(6):1673-82. (PMID: 16778289)
Biochim Biophys Acta. 2013 Jun;1832(6):754-62. (PMID: 23416528)
Circulation. 2008 Nov 11;118(20):2057-62. (PMID: 18955667)
J Exp Med. 2007 Nov 26;204(12):3037-47. (PMID: 18025128)
J Mol Cell Cardiol. 2000 Dec;32(12):2397-402. (PMID: 11113015)
Transfusion. 2007 Sep;47(9):1725-32. (PMID: 17725740)
Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):E4098-107. (PMID: 24101459)
N Engl J Med. 2007 Sep 13;357(11):1121-35. (PMID: 17855673)
Methods Mol Biol. 2007;357:271-96. (PMID: 17172694)
J Cell Biol. 1993 Oct;123(2):485-96. (PMID: 7691831)
N Engl J Med. 1996 Oct 17;335(16):1182-9. (PMID: 8815940)
Matrix Biol. 2014 Jul;37:92-101. (PMID: 24418252)
Thromb Haemost. 2011 May;105(5):873-82. (PMID: 21384080)
معلومات مُعتمدة: DP2 HL132390 United States HL NHLBI NIH HHS; R01 HL122309 United States HL NHLBI NIH HHS; UL1 TR001422 United States TR NCATS NIH HHS
فهرسة مساهمة: Keywords: CD47; macrophage; phagocytosis
تواريخ الأحداث: Date Created: 20170919 Latest Revision: 20201001
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC5595371
DOI: 10.1016/j.jacbts.2017.03.013
PMID: 28920097
قاعدة البيانات: MEDLINE
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