دورية أكاديمية
Genetic and pathogenic characterization of a Russian subtype 2 PRRSV-1 isolate.
العنوان: | Genetic and pathogenic characterization of a Russian subtype 2 PRRSV-1 isolate. |
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المؤلفون: | Yuzhakov AG; Laboratory of Virology, Diagnostics and Prevention Research Institute for Human and Animal Diseases, Moscow, Russia. Electronic address: anton_oskol@mail.ru., Raev SA; Laboratory of Virology, Diagnostics and Prevention Research Institute for Human and Animal Diseases, Moscow, Russia. Electronic address: raevsergey@mail.ru., Skrylev AN; Siberian Agrarian Group, Tomsk, Russia. Electronic address: shan.70@yandex.ru., Mishin AM; Laboratory of Virology, Diagnostics and Prevention Research Institute for Human and Animal Diseases, Moscow, Russia. Electronic address: doktor-mishin@mail.ru., Grebennikova TV; Laboratory of Virology, Diagnostics and Prevention Research Institute for Human and Animal Diseases, Moscow, Russia. Electronic address: t_grebennikova@mail.ru., Verkhovsky OA; Laboratory of Virology, Diagnostics and Prevention Research Institute for Human and Animal Diseases, Moscow, Russia. Electronic address: info@dpri.ru., Zaberezhny AD; All-Russian Research Institute of Experimental Veterinary Medicine named Ya. R. Kovalenko, Moscow, Russia. Electronic address: zaberezhny@mail.ru., Trus I; Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium. Electronic address: ivan.trus@ugent.be., Nauwynck HJ; Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium. Electronic address: hans.nauwynck@ugent.be., Aliper TI; All-Russian Research Institute of Experimental Veterinary Medicine named Ya. R. Kovalenko, Moscow, Russia. Electronic address: aliper@narvac.com. |
المصدر: | Veterinary microbiology [Vet Microbiol] 2017 Nov; Vol. 211, pp. 22-28. Date of Electronic Publication: 2017 Sep 22. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Elsevier Scientific Pub. Co Country of Publication: Netherlands NLM ID: 7705469 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2542 (Electronic) Linking ISSN: 03781135 NLM ISO Abbreviation: Vet Microbiol Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Amsterdam, Elsevier Scientific Pub. Co. |
مواضيع طبية MeSH: | Genome, Viral/*genetics , Porcine Reproductive and Respiratory Syndrome/*virology , Porcine respiratory and reproductive syndrome virus/*pathogenicity , Viremia/*veterinary, Amino Acid Sequence ; Animals ; Lung/virology ; Phylogeny ; Porcine respiratory and reproductive syndrome virus/genetics ; Porcine respiratory and reproductive syndrome virus/isolation & purification ; Random Allocation ; Russia ; Sequence Alignment/veterinary ; Swine ; Viral Load/veterinary ; Viremia/virology ; Virulence |
مستخلص: | Porcine reproductive and respiratory syndrome virus (PRRSV) causes reproductive failure and respiratory problems. Data about the virulence and pathogenicity of subtype 2 PRRSV-1 strains are limited. The main purposes of this investigation were to characterize the full genome sequence of the subtype 2 PRRSV-1 WestSib13 strain and to compare the pathogenicity with that of the subtype 1 PRRSV-1 Lelystad strain. Comparison of the whole genome sequence of the WestSib13 strain with that of PRRSV-1 prototype strains revealed a 76.2% (subtype 1 Lelystad virus) and 79.0% (subtype 3 Lena virus) identity, respectively The virulence and pathogenicity of the European subtype 2 PRRSV strain WestSib13 and the European subtype 1 PRRSV strain Lelystad were compared in 3-week-old piglets upon inoculation of 10 5.4 TCID (Copyright © 2017 Elsevier B.V. All rights reserved.) |
فهرسة مساهمة: | Keywords: Fever; Genome; Mortality; PRRSV; Pathogenicity; Subtype 2; Virulence |
تواريخ الأحداث: | Date Created: 20171106 Date Completed: 20180702 Latest Revision: 20180702 |
رمز التحديث: | 20240628 |
DOI: | 10.1016/j.vetmic.2017.09.017 |
PMID: | 29102117 |
قاعدة البيانات: | MEDLINE |
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