دورية أكاديمية
What do Cochrane systematic reviews say about probiotics as preventive interventions?
| العنوان: | What do Cochrane systematic reviews say about probiotics as preventive interventions? |
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| المؤلفون: | Braga VL; Undergraduate Medical Student, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (Unifesp), São Paulo (SP), Brazil., Rocha LPDS; Undergraduate Medical Students, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (Unifesp), São Paulo (SP), Brazil., Bernardo DD; Undergraduate Medical Students, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (Unifesp), São Paulo (SP), Brazil., Cruz CO; MD, MSc. Psychologist, Postgraduate Student, Evidence-Based Health Program, Universidade Federal de São Paulo (Unifesp), and Assistant Researcher, Cochrane Brazil, São Paulo (SP), Brazil., Riera R; MD, PhD. Rheumatologist, Adjunct Professor, Discipline of Evidence-Based Medicine, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (Unifesp), and Assistant Coordinator, Cochrane Brazil, São Paulo (SP), Brazil. |
| المصدر: | Sao Paulo medical journal = Revista paulista de medicina [Sao Paulo Med J] 2017 Nov-Dec; Vol. 135 (6), pp. 578-586. |
| نوع المنشور: | Journal Article; Comment |
| اللغة: | English |
| بيانات الدورية: | Publisher: Associação Paulista de Medicina Country of Publication: Brazil NLM ID: 100897261 Publication Model: Print Cited Medium: Internet ISSN: 1806-9460 (Electronic) Linking ISSN: 15163180 NLM ISO Abbreviation: Sao Paulo Med J Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: São Paulo, S.P., Brazil : Associação Paulista de Medicina, [1994- |
| مواضيع طبية MeSH: | Diarrhea* , Probiotics*, Anti-Bacterial Agents ; Evidence-Based Medicine ; Female ; Incidence ; Pregnancy |
| مستخلص: | Background: Probiotics have been used for a range of clinical situations and their use is strongly encouraged by the media worldwide. This study identified and summarized all Cochrane systematic reviews about the preventive effects of probiotics in clinical practice. Design and Setting: Review of systematic reviews, conducted in the Discipline of Evidence-Based Medicine, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (Unifesp). Methods: We included all Cochrane reviews on any probiotics when they were used as preventive interventions and compared with no intervention, placebo or any other pharmacological or non-pharmacological intervention. Results: 17 Cochrane systematic reviews fulfilled our inclusion criteria and were summarized in this report. None of the reviews included in the present study provided high-quality evidence for any outcome. The benefits from use of probiotics included decreased incidence of antibiotic-associated diarrhea and Clostridium difficile-associated diarrhea; decreased incidence of upper respiratory tract infections and duration of episodes; decreased need for antibiotics and absences from school due to colds; and decreased incidence of ventilator-associated pneumonia. Probiotics seem to decrease the incidence of gestational diabetes mellitus, birthweight, risk of vaginal infection and incidence of eczema. Conclusion: Despite the marketing and the benefits associated with probiotics, there is little scientific evidence supporting the use of probiotics. None of the reviews provided any high-quality evidence for prevention of illnesses through use of probiotics. More trials are needed to gain better knowledge of probiotics and to confirm when their use is beneficial and cost-effective. |
| التعليقات: | Comment on: Cochrane Database Syst Rev. 2006 Oct 18;(4):CD004826. (PMID: 17054217) Comment on: Cochrane Database Syst Rev. 2008 Jan 23;(1):CD005496. (PMID: 18254081) Comment on: Cochrane Database Syst Rev. 2009 Oct 07;(4):CD006873. (PMID: 19821389) Comment on: Cochrane Database Syst Rev. 2011 Aug 10;(8):CD008739. (PMID: 21833970) Comment on: Cochrane Database Syst Rev. 2011 Nov 09;(11):CD004827. (PMID: 22071814) Comment on: Cochrane Database Syst Rev. 2011 Nov 09;(11):CD006933. (PMID: 22071832) Comment on: Cochrane Database Syst Rev. 2011 Dec 07;(12):CD007443. (PMID: 22161412) Comment on: Cochrane Database Syst Rev. 2013 May 31;(5):CD006095. (PMID: 23728658) Comment on: Cochrane Database Syst Rev. 2014 Feb 27;(2):CD009951. (PMID: 24574258) Comment on: Cochrane Database Syst Rev. 2014 Mar 05;(3):CD006660. (PMID: 24599680) Comment on: Cochrane Database Syst Rev. 2014 Oct 25;(10):CD009066. (PMID: 25344083) Comment on: Cochrane Database Syst Rev. 2015 Feb 03;(2):CD006895. (PMID: 25927096) Comment on: Cochrane Database Syst Rev. 2015 Nov 23;(11):CD001176. (PMID: 26593456) Comment on: Cochrane Database Syst Rev. 2015 Dec 23;(12):CD008772. (PMID: 26695595) |
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| المشرفين على المادة: | 0 (Anti-Bacterial Agents) |
| تواريخ الأحداث: | Date Created: 20171222 Date Completed: 20180605 Latest Revision: 20230317 |
| رمز التحديث: | 20240829 |
| مُعرف محوري في PubMed: | PMC10016009 |
| DOI: | 10.1590/1516-3180.2017.0310241017 |
| PMID: | 29267517 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1806-9460 |
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| DOI: | 10.1590/1516-3180.2017.0310241017 |