دورية أكاديمية
Delay from symptom onset to treatment start among tuberculosis patients in England, 2012-2015.
| العنوان: | Delay from symptom onset to treatment start among tuberculosis patients in England, 2012-2015. |
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| المؤلفون: | Loutet MG; National Infection Service, Public Health England,London,UK., Sinclair C; National Infection Service, Public Health England,London,UK., Whitehead N; Queen Alexandra Hospital,Portsmouth,UK., Cosgrove C; St George's University Hospitals NHS Foundation Trust,London,UK., Lalor MK; National Infection Service, Public Health England,London,UK., Thomas HL; National Infection Service, Public Health England,London,UK. |
| المصدر: | Epidemiology and infection [Epidemiol Infect] 2018 Sep; Vol. 146 (12), pp. 1511-1518. Date of Electronic Publication: 2018 Jun 20. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Cambridge University Press Country of Publication: England NLM ID: 8703737 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-4409 (Electronic) Linking ISSN: 09502688 NLM ISO Abbreviation: Epidemiol Infect Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Cambridge Eng : Cambridge University Press |
| مواضيع طبية MeSH: | Delayed Diagnosis* , Time-to-Treatment*, Tuberculosis/*diagnosis , Tuberculosis/*drug therapy, Adult ; England/epidemiology ; Female ; Health Services Accessibility ; Humans ; Male ; Middle Aged ; Population Surveillance ; Retrospective Studies ; Risk Factors ; Tuberculosis/epidemiology ; Tuberculosis/transmission |
| مستخلص: | Improving access to tuberculosis (TB) care and ensuring early diagnosis are two major aims of the WHO End TB strategy and the Collaborative TB Strategy for England. This study describes risk factors associated with diagnostic delay among TB cases in England. We conducted a retrospective cohort study of TB cases notified to the Enhanced TB Surveillance System in England between 2012 and 2015. Diagnostic delay was defined as more than 4 months between symptom onset and treatment start date. Multivariable logistic regression was used to identify demographic and clinical factors associated with diagnostic delay. Between 2012 and 2015, 22 422 TB cases were notified in England and included in the study. A third (7612) of TB cases had a diagnostic delay of more than 4 months. Being female, aged 45 years and older, residing outside of London and having extra-pulmonary TB disease were significantly associated with a diagnostic delay in the multivariable model (aOR = 1.2, 1.2, 1.2, 1.3, 1.8, respectively). This study identifies demographic and clinical factors associated with diagnostic delay, which will inform targeted interventions to improve access to care and early diagnosis among these groups, with the ultimate aim of helping reduce transmission and improve treatment outcomes for TB cases in England. |
| References: | Int J Tuberc Lung Dis. 2004 Feb;8(2):180-5. (PMID: 15139446) BMC Med. 2017 Jun 13;15(1):105. (PMID: 28606177) BMC Infect Dis. 2016 Nov 11;16(1):673. (PMID: 27836012) Rev Bras Epidemiol. 2015 Oct-Dec;18(4):809-23. (PMID: 26982297) Int J Tuberc Lung Dis. 1999 May;3(5):388-93. (PMID: 10331727) Kekkaku. 2010 Aug;85(8):655-60. (PMID: 20845684) BMC Public Health. 2016 Aug 08;16:740. (PMID: 27503095) Int J Prev Med. 2016 Oct 26;7:116. (PMID: 27857829) Public Health. 2013 Feb;127(2):171-7. (PMID: 23313162) Int J Tuberc Lung Dis. 2013 Sep;17(9):1199-205. (PMID: 23928169) Int J Tuberc Lung Dis. 2006 Jan;10(1):24-30. (PMID: 16466033) BMJ. 2003 Apr 26;326(7395):909-10. (PMID: 12714470) Am J Respir Crit Care Med. 2009 Nov 15;180(10):1016-22. (PMID: 19679694) Emerg Infect Dis. 2017 Mar;23(3):448-455. (PMID: 28221133) Eur Respir J. 2015 Apr;45(4):928-52. (PMID: 25792630) PLoS Med. 2016 Sep 06;13(9):e1002119. (PMID: 27598345) Am J Infect Control. 2013 Feb;41(2):155-60. (PMID: 22750037) BMJ Open. 2014 Jun 10;4(6):e004818. (PMID: 24916087) Int J Tuberc Lung Dis. 2012 Nov;16(11):1461-7. (PMID: 22981252) Rev Panam Salud Publica. 2016 Jan;39(1):12-18. (PMID: 27754530) BMJ Open. 2015 Sep 21;5(9):e008050. (PMID: 26391630) |
| فهرسة مساهمة: | Keywords: Diagnostic delay; treatment delay; tuberculosis |
| تواريخ الأحداث: | Date Created: 20180621 Date Completed: 20190401 Latest Revision: 20221006 |
| رمز التحديث: | 20221213 |
| مُعرف محوري في PubMed: | PMC9507939 |
| DOI: | 10.1017/S095026881800167X |
| PMID: | 29923481 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1469-4409 |
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| DOI: | 10.1017/S095026881800167X |