دورية أكاديمية
Relationship between abdominal adiposity and incident chronic kidney disease in young- to middle-aged working men: a retrospective cohort study.
العنوان: | Relationship between abdominal adiposity and incident chronic kidney disease in young- to middle-aged working men: a retrospective cohort study. |
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المؤلفون: | Kuma A; Second Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, 807-8555, Japan. akihiro_k@me.com.; Blood Purification Unit, Hamamatsu University Hospital, 1-20-1 Handayama, Higashi-ku, Hamamatsu, 431-3125, Japan. akihiro_k@me.com.; Health Care Center, Central Japan Railway Company, 1-21-19 Meieki-Minami, Nakamura-ku, Nagoya, 450-0003, Japan. akihiro_k@me.com., Uchino B; Health Promotion Center, Yamaha Motor Co., Ltd., 2500 Shingai, Iwata, 438-8501, Japan., Ochiai Y; Health Promotion Center, Yamaha Motor Co., Ltd., 2500 Shingai, Iwata, 438-8501, Japan., Kawashima M; Health Care Center, Central Japan Railway Company, 1-21-19 Meieki-Minami, Nakamura-ku, Nagoya, 450-0003, Japan., Enta K; Health Care Center, Central Japan Railway Company, 1-21-19 Meieki-Minami, Nakamura-ku, Nagoya, 450-0003, Japan., Tamura M; Kidney Center, University Hospital of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, 807-8556, Japan., Otsuji Y; Second Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, 807-8555, Japan., Kato A; Blood Purification Unit, Hamamatsu University Hospital, 1-20-1 Handayama, Higashi-ku, Hamamatsu, 431-3125, Japan. |
المصدر: | Clinical and experimental nephrology [Clin Exp Nephrol] 2019 Jan; Vol. 23 (1), pp. 76-84. Date of Electronic Publication: 2018 Jun 27. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Springer Country of Publication: Japan NLM ID: 9709923 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1437-7799 (Electronic) Linking ISSN: 13421751 NLM ISO Abbreviation: Clin Exp Nephrol Subsets: MEDLINE |
أسماء مطبوعة: | Publication: 2008- : Tokyo : Springer Original Publication: Tokyo : Published for the Japanese Society of Nephrology by Churchill Livingstone, c1997- |
مواضيع طبية MeSH: | Adiposity*, Obesity, Abdominal/*complications , Obesity, Abdominal/*epidemiology , Renal Insufficiency, Chronic/*complications , Renal Insufficiency, Chronic/*epidemiology, Adult ; Aging ; Body Mass Index ; Cohort Studies ; Diabetes Mellitus/epidemiology ; Follow-Up Studies ; Glomerular Filtration Rate ; Humans ; Hypertension/complications ; Hypertension/epidemiology ; Japan/epidemiology ; Male ; Middle Aged ; Reference Values ; Retrospective Studies ; Risk Factors ; Waist Circumference ; Young Adult |
مستخلص: | Background: Obesity is a risk factor for the development of chronic kidney disease (CKD). However, it remains to be fully examined whether fatness is more useful in predicting incident CKD. We aimed this study to determine the association of body fat, body mass index and waist circumference (WC) with subsequent changes in estimated glomerular filtration rate (eGFR) and incident CKD in young- to middle-aged working men. Methods: We analyzed data from annual health check-up in male workers aged from 20 to 60 years with basal eGFR of 60-90 mL/min/1.73 m 2 . Cut-off values of parameters and odds ratio (OR) for the incident CKD were calculated by receiver operator characteristics analysis andχ 2 test, respectively. We also tested trends of changes in eGFR according to changes in WC in each age decade. Results: There were 8,015 men participants. During the 5-year follow-up, 11.0% of the participants (N = 878) had developed to incident CKD. When basal WC was greater than 80.0 cm, which was decided by Youden's Index, there was a significantly higher risk of incident CKD [OR 1.57 (95% confident interval 1.35-1.84)]. Changes in WC over 5 years were significantly related to eGFR decline in young men (< 40 years old) with normal blood pressures and normoglycemia. Conclusions: These findings suggest that WC > 80.0 cm is a risk factor for incident CKD and strongly associated with a decline in eGFR in the young- to middle-aged working healthy men. |
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فهرسة مساهمة: | Keywords: Body mass index; Chronic kidney disease; Total body fatness; Waist circumference; Working men |
تواريخ الأحداث: | Date Created: 20180629 Date Completed: 20190529 Latest Revision: 20200225 |
رمز التحديث: | 20231215 |
DOI: | 10.1007/s10157-018-1606-y |
PMID: | 29951724 |
قاعدة البيانات: | MEDLINE |
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