دورية أكاديمية
Double resonance ejection using novel radiofrequency phase tracking circuitry in a miniaturized planar linear ion trap mass spectrometer.
| العنوان: | Double resonance ejection using novel radiofrequency phase tracking circuitry in a miniaturized planar linear ion trap mass spectrometer. |
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| المؤلفون: | Decker TK; Electrical and Computer Engineering Department, Brigham Young University, Provo, UT, 84602-0002, USA., Zheng Y; Chemistry and Biochemistry Department, Brigham Young University, Provo, UT, 84602-0002, USA., McClellan JS; Electrical and Computer Engineering Department, Brigham Young University, Provo, UT, 84602-0002, USA., Ruben AJ; Electrical and Computer Engineering Department, Brigham Young University, Provo, UT, 84602-0002, USA., Lammert SA; PerkinElmer Inc., 732 E 930 S, American Fork, UT, 84003, USA., Austin DE; Chemistry and Biochemistry Department, Brigham Young University, Provo, UT, 84602-0002, USA., Hawkins AR; Electrical and Computer Engineering Department, Brigham Young University, Provo, UT, 84602-0002, USA. |
| المصدر: | Rapid communications in mass spectrometry : RCM [Rapid Commun Mass Spectrom] 2018 Dec 15; Vol. 32 (23), pp. 2024-2030. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: John Wiley And Sons Ltd Country of Publication: England NLM ID: 8802365 Publication Model: Print Cited Medium: Internet ISSN: 1097-0231 (Electronic) Linking ISSN: 09514198 NLM ISO Abbreviation: Rapid Commun Mass Spectrom Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Publication: Chichester : John Wiley And Sons Ltd Original Publication: London, UK : Heyden, c1987- |
| مستخلص: | Rationale: Ion trap mass spectrometers are attractive due to their inherent sensitivity and specificity. Miniaturization increases trap portability for in situ mass analysis by relaxing vacuum and voltage requirements but decreases the trapping volume. To overcome signal/resolution loss from miniaturization, double resonance ejection using phase tracking circuitry was investigated. Methods: Phase tracking circuitry was developed to induce double resonance ejection in a planar linear ion trap using the β 2/3 hexapole resonance line. Results: Double resonance was observed using phase tracking circuitry. Resolution of 0.5 m/z units and improved signal-to-noise ratio (SNR) compared with AC resonant ejection were achieved. Conclusions: The phase tracking circuitry proved effective despite deviations from a true phase locked condition. Double resonance ejection is a means to increase signal intensity in a miniaturized planar ion trap. (© 2018 John Wiley & Sons, Ltd.) |
| معلومات مُعتمدة: | 1404886 National Science Foundation |
| تواريخ الأحداث: | Date Created: 20180823 Date Completed: 20181107 Latest Revision: 20181107 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1002/rcm.8267 |
| PMID: | 30133876 |
| قاعدة البيانات: | MEDLINE |
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