دورية أكاديمية
First retrospective studies with etiological confirmation of porcine transmissible gastroenteritis virus infection in Argentina.
| العنوان: | First retrospective studies with etiological confirmation of porcine transmissible gastroenteritis virus infection in Argentina. |
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| المؤلفون: | Piñeyro PE; Veterinary Diagnostic Laboratory, 1655 Veterinary Medicine, Iowa State University, 1850 Christensen Drive, Ames, IA, 50011, USA. pablop@iastate.edu., Lozada MI; Laboratorio de Patología Especial Veterinaria FCV-UNLP, Calle 60 y 118 S/N (1900), La Plata, Buenos Aires, Argentina., Alarcón LV; HIPRA Argentina, Saenz Peña R. Pte. Av 1110, Capital Federal, Argentina., Sanguinetti R; DILACOT-SENASA, Av A Fleming 1653, Martinez, Buenos Aires, Argentina., Cappuccio JA; EEA Marcos Juaréz, INTA, CONICET, Ruta 12 km. 3 (2580), Marcos Juárez, Córdoba, Argentina., Pérez EM; Laboratorio de Patología Especial Veterinaria FCV-UNLP, Calle 60 y 118 S/N (1900), La Plata, Buenos Aires, Argentina., Vannucci F; Veterinary Diagnostic Laboratory, University of Minnesota, 1333 Gortner Ave, St Paul, MN, USA., Armocida A; Laboratorio de Patología Especial Veterinaria FCV-UNLP, Calle 60 y 118 S/N (1900), La Plata, Buenos Aires, Argentina., Madson DM; Veterinary Diagnostic Laboratory, 1655 Veterinary Medicine, Iowa State University, 1850 Christensen Drive, Ames, IA, 50011, USA., Perfumo CJ; Laboratorio de Patología Especial Veterinaria FCV-UNLP, Calle 60 y 118 S/N (1900), La Plata, Buenos Aires, Argentina., Quiroga MA; Laboratorio de Patología Especial Veterinaria FCV-UNLP, Calle 60 y 118 S/N (1900), La Plata, Buenos Aires, Argentina. |
| المصدر: | BMC veterinary research [BMC Vet Res] 2018 Sep 24; Vol. 14 (1), pp. 292. Date of Electronic Publication: 2018 Sep 24. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: BioMed Central Country of Publication: England NLM ID: 101249759 Publication Model: Electronic Cited Medium: Internet ISSN: 1746-6148 (Electronic) Linking ISSN: 17466148 NLM ISO Abbreviation: BMC Vet Res Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: London : BioMed Central, 2005- |
| مواضيع طبية MeSH: | Gastroenteritis, Transmissible, of Swine/*diagnosis , Swine Diseases/*diagnosis , Transmissible gastroenteritis virus/*isolation & purification, Animals ; Argentina/epidemiology ; Female ; Gastroenteritis, Transmissible, of Swine/epidemiology ; Male ; Retrospective Studies ; Swine ; Swine Diseases/epidemiology |
| مستخلص: | Background: In 2014, a notification of porcine transmissible gastroenteritis virus (TGEV) was made by the National Services of Animal Health of Argentina (SENASA) to the World Organization of Animal Health (OIE). The notification was based on a serological diagnosis in a small farm with a morbidity rate of 2.3% without enteric clinical signs. In order to determine if TGEV was circulating before the official report, a retrospective study on cases of neonatal diarrhea was performed. The selection criteria was a sudden increase in mortality in 1- to 21-day-old piglets with watery diarrhea that did not respond to antibiotics. Based on these criteria, three clinical cases were identified during 2010-2015. Results: All animals that were evaluated presented histological lesions consistent with enteric viral infection. The feces and ultrathin sections of intestine that were evaluated by electron microscopy confirmed the presence of round particles of approximately 80 nm in size and characterized by finely granular electrodense nucleoids consistent with complete particles of coronavirus. The presence of the TGEV antigen was confirmed by monoclonal specific immunohistochemistry, and final confirmation of a metabolically-active virus was performed by in situ hybridization to detect a TGE mRNA encoding spike protein. All sections evaluated in this case were negative for PEDV and rotavirus A. Conclusions: This is the first case series describing neonatal mortality with etiological confirmation of TGEV in Argentina. The clinical diagnosis of TGEV infections in endemic regions is challenging due to the epidemiological distribution and coinfection with other enteric pathogens that mask the clinical presentation. |
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| فهرسة مساهمة: | Keywords: Diarrhea; Mortality; Piglets; Porcine transmissible gastroenteritis virus |
| تواريخ الأحداث: | Date Created: 20180926 Date Completed: 20181211 Latest Revision: 20181211 |
| رمز التحديث: | 20240829 |
| مُعرف محوري في PubMed: | PMC6154422 |
| DOI: | 10.1186/s12917-018-1615-9 |
| PMID: | 30249258 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1746-6148 |
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| DOI: | 10.1186/s12917-018-1615-9 |