Unsuspected Skin Metastasis of Adenocarcinoma of the Prostate in a Patient on Goserelin (Zoladex).

التفاصيل البيبلوغرافية
العنوان: Unsuspected Skin Metastasis of Adenocarcinoma of the Prostate in a Patient on Goserelin (Zoladex).
المؤلفون: Mbaeri TU; Department of Surgery, Division of Urology, Nnamdi Azikiwe University, Awka, Nigeria., Orakwe JC; Department of Surgery, Division of Urology, Nnamdi Azikiwe University, Awka, Nigeria., Ezejiofor OI; Deparment of Internal Medicine, Nnamdi Azikiwe University, Awka, Nigeria.
المصدر: Nigerian journal of surgery : official publication of the Nigerian Surgical Research Society [Niger J Surg] 2018 Jul-Dec; Vol. 24 (2), pp. 138-141.
نوع المنشور: Case Reports
اللغة: English
بيانات الدورية: Publisher: Medknow Country of Publication: India NLM ID: 101189891 Publication Model: Print Cited Medium: Print ISSN: 1117-6806 (Print) Linking ISSN: 11176806 NLM ISO Abbreviation: Niger J Surg Subsets: PubMed not MEDLINE
أسماء مطبوعة: Publication: <2011-2021> : Mumbai : Medknow
Original Publication: Lagos, Nigeria : Nigerian Surgical Research Society
مستخلص: Prostate cancer remains the most common noncutaneous cancer in men, especially in this era of prostate-specific antigen assay. Prostate cancer metastases have been known to commonly affect the lymphatics, bones, and lungs. Prostate cancer metastasis to the skin is very rare (<1%) and often signifies a terminal disease. Involvement of the skin has been thought to be through lymphatic spread by embolization or permeation, hematogenous spread, and implantation during surgery (port site in radical prostatectomy). We report a 74-year-old man on management for advanced prostate cancer with subcutaneous goserelin (Zoladex) but developed skin metastasis in the course of treatment. The skin metastasis in our patient, however, was initially localized to the site of the regions of subcutaneous goserelin injection that we imagined if there is a link between the two. We reviewed the literature and currently found no connection. Is there truly a link?
Competing Interests: There are no conflicts of interest.
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فهرسة مساهمة: Keywords: Goserelin; prostate cancer; skin metastasis
تواريخ الأحداث: Date Created: 20181005 Latest Revision: 20201001
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC6158991
DOI: 10.4103/njs.NJS_15_17
PMID: 30283228
قاعدة البيانات: MEDLINE