دورية أكاديمية
Exercise training reduces oxidative stress in people living with HIV/AIDS: a pilot study.
| العنوان: | Exercise training reduces oxidative stress in people living with HIV/AIDS: a pilot study. |
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| المؤلفون: | Deresz LF; a Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA) , Porto Alegre , RS , Brazil.; b Physical Education Department, Institute of Life Sciences , Universidade Federal de Juiz de Fora, Campus Governador Valadares , MG , Brazil., Schöler CM; c Laboratory of Cellular Physiology, Institute of Basic Health Sciences , Universidade Federal do Rio Grande do Sul , Porto Alegre , RS , Brazil., de Bittencourt PIHJ; c Laboratory of Cellular Physiology, Institute of Basic Health Sciences , Universidade Federal do Rio Grande do Sul , Porto Alegre , RS , Brazil., Karsten M; d Physical Therapy Department , Universidade do Estado de Santa Catarina (UDESC) , Florianópolis , SC , Brazil., Ikeda MLR; e Nursing Department , Universidade do Vale do Rio dos Sinos , São Leopoldo , RS , Brazil.; f Health Secretariat of State of Rio Grande do Sul , Porto Alegre , RS , Brazil., Sonza A; d Physical Therapy Department , Universidade do Estado de Santa Catarina (UDESC) , Florianópolis , SC , Brazil., Dal Lago P; a Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA) , Porto Alegre , RS , Brazil.; g Physical Therapy Department , UFCSPA , Porto Alegre , RS , Brazil. |
| المصدر: | HIV clinical trials [HIV Clin Trials] 2018 Aug; Vol. 19 (4), pp. 152-157. Date of Electronic Publication: 2018 Oct 27. |
| نوع المنشور: | Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Taylor & Francis Country of Publication: England NLM ID: 100936377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1945-5771 (Electronic) Linking ISSN: 15284336 NLM ISO Abbreviation: HIV Clin Trials Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2016-2018 : Abingdon : Taylor & Francis Original Publication: St. Louis, MO : Thomas Land Publishers, c2000- |
| مواضيع طبية MeSH: | Exercise* , Oxidative Stress*, HIV Infections/*metabolism, Anti-HIV Agents/administration & dosage ; Anti-HIV Agents/therapeutic use ; Antiretroviral Therapy, Highly Active ; Humans ; Pilot Projects ; Viral Load |
| مستخلص: | Background: Exercise training has been shown to be an effective strategy to balance oxidative stress status; however, this is underexplored in people living with HIV/AIDS (PLWHA). Objective: To evaluate the effects of exercise training on oxidative stress in PLWHA receiving antiretroviral therapy. Methods: Patients performed 24 sessions (3 times per week, 8 weeks) of either aerobic (AT), resistance (RT), or concurrent training (CT). Glutathione disulphide to glutathione ratio (GSSG/GSH) in circulating erythrocytes and thiobarbituric acid-reactive substances (TBARS) in plasma samples were assessed as oxidative stress markers. Eight PLWAH completed the training protocol (AT =3, RT =3, CT =2). The GSSG/GSH and TBARS values were logarithmically transformed to approximate a normal distribution. A paired t-test was used to determine the differences between baseline and post-training values. Results: Data-pooled analysis showed a decrease in GSSG/GSH and TBARS after the training period: log GSSG/GSH= -1.26 ± 0.57 versus -1.54 ± 0.65, p = .01 and log TBARS =0.73 ± 0.35 versus 0.43 ± 0.21, p = .01. This was paralleled by a rise in peak oxygen uptake (VO |
| فهرسة مساهمة: | Keywords: AIDS; aerobic exercise; antiretroviral therapy; oxidative stress; strength training |
| المشرفين على المادة: | 0 (Anti-HIV Agents) |
| تواريخ الأحداث: | Date Created: 20181030 Date Completed: 20190613 Latest Revision: 20190613 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1080/15284336.2018.1481247 |
| PMID: | 30369300 |
| قاعدة البيانات: | MEDLINE |
PDF full text from Publisher | تدمد: | 1945-5771 |
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| DOI: | 10.1080/15284336.2018.1481247 |