25-Hydroxy cholecalciferol, anti-Müllerian hormone, and thyroid profiles among infertile men.

التفاصيل البيبلوغرافية
العنوان:	25-Hydroxy cholecalciferol, anti-Müllerian hormone, and thyroid profiles among infertile men.
المؤلفون:	Hassan MH; Medical Biochemistry Department, Faculty of Medicine, South Valley University, Qena, Egypt., Ibrahim HM; Department of Dermatology, Venereology and Andrology, Faculty of Medicine, South Valley University, Qena, Egypt., El-Taieb MA; Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Aswan University, Aswan, Egypt.
المصدر:	The aging male : the official journal of the International Society for the Study of the Aging Male [Aging Male] 2020 Dec; Vol. 23 (5), pp. 513-519. Date of Electronic Publication: 2018 Nov 22.
نوع المنشور:	Journal Article
اللغة:	English
بيانات الدورية:	Publisher: Taylor & Francis Country of Publication: England NLM ID: 9808210 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1473-0790 (Electronic) Linking ISSN: 13685538 NLM ISO Abbreviation: Aging Male Subsets: MEDLINE
أسماء مطبوعة:	Publication: 2015- : Abingdon, Oxford : Taylor & Francis Original Publication: New York : Parthenon Pub., c1998-
مواضيع طبية MeSH:	Anti-Mullerian Hormone* , Thyroid Gland*, Cholecalciferol ; Cross-Sectional Studies ; Follicle Stimulating Hormone ; Humans ; Male
مستخلص:	Background and Aim: We examined the relationship among vit.D 3 , AMH, FT3, FT4, and TSH, in addition to the serum levels of reproductive hormones (FSH, LH, prolactin, and free testosterone), in oligoasthenoteratozoospermia and azoospermia patients in a cohort of infertile men from Egypt to establish a clinical marker/cause-effect relationship. Methods: This cross-sectional cohort study was carried out on 301 men (105 males with oligoasthenoteratozoospermia and 96 males with azoospermia), in addition to 100 controls. Measurements of serum vit.D 3 , AMH, FT3, FT4, and TSH levels, in addition to reproductive hormone assays, were performed on all included subjects, using ELISA kits. Results: Overall, results showed significantly lower serum levels of vit.D 3 in infertile men than in the controls, with a greater decrease observed in men with azoospermia than in oligoasthenoteratozoospermia patients, ( p < .05 for all). Significantly higher serum TSH and FSH levels and significantly lower serum free testosterone levels were observed in males with azoospermia than in males with oligoasthenoteratozoospermia and the controls ( p < .05 for both). There were no significant differences between the studied groups in terms of AMH, FT3 or FT4 levels. LH levels were negatively correlated with TSH levels and positively correlated with AMH levels among men with oligoasthenoteratozoospermia, while among men with azoospermia, LH levels were positively correlated with vit.D 3 levels ( p < .05 for all). Conclusion: Decreased Vit.D 3 could play a role in male infertility, in addition to abnormal thyroid function, which needs further investigation.
فهرسة مساهمة:	Keywords: Anti-Müllerian hormone; male infertility; thyroid function; vit.D3
المشرفين على المادة:	1C6V77QF41 (Cholecalciferol) 80497-65-0 (Anti-Mullerian Hormone) 9002-68-0 (Follicle Stimulating Hormone)
تواريخ الأحداث:	Date Created: 20181123 Date Completed: 20211025 Latest Revision: 20220422
رمز التحديث:	20231215
DOI:	10.1080/13685538.2018.1538338
PMID:	30465464
قاعدة البيانات:	MEDLINE

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