دورية أكاديمية
Analysis of infectious spondylodiscitis: 7-years data.
| العنوان: | Analysis of infectious spondylodiscitis: 7-years data. |
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| المؤلفون: | Okay G; Gulay Okay, MD. Department of Infectious Diseases and Clinical Microbiology, Bezmialem Vakif University, Istanbul, Turkey., Akkoyunlu Y; Yasemin Akkoyunlu, Associate Professor. Department of Infectious Diseases and Clinical Microbiology, Bezmialem Vakif University, Istanbul, Turkey., Bolukcu S; Sibel Bolukcu, MD Department of Infectious Diseases and Clinical Microbiology, Bezmialem Vakif University, Istanbul, Turkey., Durdu B; Bulent Durdu, Assistant Professor. Department of Infectious Diseases and Clinical Microbiology, Bezmialem Vakif University, Istanbul, Turkey., Hakyemez IN; Ismail Necati Hakyemez, Associate Professor. Department of Infectious Diseases and Clinical Microbiology, Bezmialem Vakif University, Istanbul, Turkey., Koc MM; Prof. Meliha Meric Koc, Department of Infectious Diseases and Clinical Microbiology, Bezmialem Vakif University, Istanbul, Turkey. |
| المصدر: | Pakistan journal of medical sciences [Pak J Med Sci] 2018 Nov-Dec; Vol. 34 (6), pp. 1445-1451. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Professional Medical Publications Country of Publication: Pakistan NLM ID: 100913117 Publication Model: Print Cited Medium: Print ISSN: 1682-024X (Print) Linking ISSN: 1681715X NLM ISO Abbreviation: Pak J Med Sci Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Karachi, Pakistan : Professional Medical Publications, [2000- |
| مستخلص: | Objective: Infectious spondylodiscitis (SD) is an infectious disease that is rare and difficult to diagnose due to its non-specific clinical features. In this study, we aimed to describe the clinical and diagnostic features of infectious spondylodiscitis. Methods: All patients who were diagnosed with SD at our hospital during a 7-year period from January 1, 2011 through December 31, 2017 were included in the study. Spondylodiscitis is divided into the following three types: pyogenic, tuberculous, and brucellar. Clinical and laboratory data were collected retrospectively from the medical records of the patients. Results: Of the 118 patients, 66 (55.9%) were female, 81 (68.6%) had pyogenic SD (PSD), 21 (17.8%) had tuberculous SD (TSD), and 16 (13.6%) had brucellar SD (BSD). The mean age was 59.3 ± 14.6 years. Leucocytosis was significantly higher in patients with PSD (p=0.01) than in patients with other types of SD. Thoracic involvement (47.6%) was significantly higher in patients with TSD (p=0.005) than in other patients. Sacral involvement (12.5%) was significantly higher in patients with BSD (p=0.01) than in other patients. Paravertebral abscess formation (42.8%) occurred most frequently in patients with TSD. Microbiologic agents were defined in 50% (18/36) of the surgical specimens and in 12.5% of the fine needle aspiration biopsy (FNAB) specimens. Staphylococcus aureus was the most common microbiological agent in patients with PSD. Spinal surgery was defined as a risk factor for PSD (p = 0.0001). Binary logistic regression analysis revealed that female gender, thoracic involvement and night sweats were the predictive markers for TSD (OR 4.5 [95% CI 1.3-15.3] and OR 5 [95% CI 1.7-14.6]). Conclusion: PSD is the most frequent form of SD. Leucocytosis is most common in patients with PSD. Thoracic involvement and paraspinal abscess were prominent in patients with TSD. Sacral involvement was most common in patients with BSD. Thoracic involvement, female gender and night sweats were the predictive markers for TSD. The microbiological culture positivity rate was higher in surgical specimens compared to FNAB specimens. The need for surgical treatment was most common in patients with TSD. Competing Interests: Conflicts Of Interest: None. |
| References: | Spine (Phila Pa 1976). 2006 Nov 1;31(23):2695-700. (PMID: 17077738) Clin Infect Dis. 2002 May 15;34(10):1342-50. (PMID: 11981730) Clin Microbiol Infect. 2015 Nov;21(11):1008.e9-1008.e18. (PMID: 26232534) J Infect Dev Ctries. 2014 Oct 15;8(10):1272-6. (PMID: 25313603) J Infect. 2008 Jun;56(6):401-12. (PMID: 18442854) Neurosurg Focus. 2014 Aug;37(2):E3. (PMID: 25081963) Clin Microbiol Infect. 2014 Oct;20(10):1055-60. (PMID: 24766063) J Neurosci Rural Pract. 2012 Jan;3(1):17-20. (PMID: 22346185) J Infect. 2014 Jul;69(1):42-50. (PMID: 24561018) Semin Arthritis Rheum. 2009 Aug;39(1):10-7. (PMID: 18550153) Spine J. 2015 Dec 1;15(12):2509-17. (PMID: 26386176) Eur J Radiol. 2004 May;50(2):120-33. (PMID: 15081128) Int Orthop. 2012 Feb;36(2):239-44. (PMID: 22215366) Lancet. 2015 Mar 7;385(9971):875-82. (PMID: 25468170) Acta Neurochir (Wien). 2018 Mar;160(3):487-496. (PMID: 29356895) Korean J Spine. 2017 Jun;14(2):27-34. (PMID: 28704905) J Infect. 2000 Mar;40(2):150-3. (PMID: 10841091) J Infect. 2007 Aug;55(2):158-63. (PMID: 17559939) Surg Neurol. 1990 Apr;33(4):266-75. (PMID: 2326732) Diagn Interv Imaging. 2012 Jun;93(6):520-9. (PMID: 22677300) BMJ Open. 2013 Mar 25;3(3):. (PMID: 23533214) Acta Orthop. 2008 Oct;79(5):650-9. (PMID: 18839372) World Neurosurg. 2013 Jul-Aug;80(1-2):190-203. (PMID: 23348057) N Engl J Med. 2010 Mar 18;362(11):1022-9. (PMID: 20237348) J Antimicrob Chemother. 2010 Nov;65 Suppl 3:iii11-24. (PMID: 20876624) Rheumatol Int. 2012 Nov;32(11):3591-7. (PMID: 22095392) |
| فهرسة مساهمة: | Keywords: Brucellar; Clinical features; Diagnosis; Infectious spondylodiscitis; Pyogenic; Tubercular |
| تواريخ الأحداث: | Date Created: 20181219 Latest Revision: 20220330 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC6290200 |
| DOI: | 10.12669/pjms.346.15717 |
| PMID: | 30559801 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1682-024X |
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| DOI: | 10.12669/pjms.346.15717 |