دورية أكاديمية
Postoperative Risk Factors and Outcome of Patients With Liver Transplantation Who Were Admitted to Pediatric Intensive Care Unit: A 10-Year Single-Center Review in China.
| العنوان: | Postoperative Risk Factors and Outcome of Patients With Liver Transplantation Who Were Admitted to Pediatric Intensive Care Unit: A 10-Year Single-Center Review in China. |
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| المؤلفون: | Qian J; Pediatric Intensive Care Unit, 71140Shanghai Children's Medical Center, School of Medicine, Shanghai Jiaotong University, Shanghai, People's Republic of China., Zhou T; Department of Liver Surgery and Liver Transplantation, 71140Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, People's Republic of China., Qiu BJ; Department of Liver Surgery and Liver Transplantation, 71140Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, People's Republic of China., Xiang L; Pediatric Intensive Care Unit, 71140Shanghai Children's Medical Center, School of Medicine, Shanghai Jiaotong University, Shanghai, People's Republic of China., Zhang J; Pediatric Intensive Care Unit, 71140Shanghai Children's Medical Center, School of Medicine, Shanghai Jiaotong University, Shanghai, People's Republic of China., Ning BT; Pediatric Intensive Care Unit, 71140Shanghai Children's Medical Center, School of Medicine, Shanghai Jiaotong University, Shanghai, People's Republic of China., Ren H; Pediatric Intensive Care Unit, 71140Shanghai Children's Medical Center, School of Medicine, Shanghai Jiaotong University, Shanghai, People's Republic of China., Li BR; Pediatric Intensive Care Unit, 71140Shanghai Children's Medical Center, School of Medicine, Shanghai Jiaotong University, Shanghai, People's Republic of China., Xia Q; Department of Liver Surgery and Liver Transplantation, 71140Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, People's Republic of China., Wang Y; Pediatric Intensive Care Unit, 71140Shanghai Children's Medical Center, School of Medicine, Shanghai Jiaotong University, Shanghai, People's Republic of China. |
| المصدر: | Journal of intensive care medicine [J Intensive Care Med] 2020 Nov; Vol. 35 (11), pp. 1241-1249. Date of Electronic Publication: 2019 May 15. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Sage Publications Country of Publication: United States NLM ID: 8610344 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-1489 (Electronic) Linking ISSN: 08850666 NLM ISO Abbreviation: J Intensive Care Med Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2002- : Thousands Oaks, CA : Sage Publications Original Publication: [Boston, MA : Little, Brown & Co., c1986- |
| مواضيع طبية MeSH: | Liver Transplantation*, Child ; Humans ; Infant ; Intensive Care Units, Pediatric ; Postoperative Period ; Retrospective Studies ; Risk Factors |
| مستخلص: | Introduction: The aim of this study was to present our 10-year experience of pediatric intensive care unit (PICU) management with pediatric liver recipients and to understand the importance of close interdisciplinary cooperation in 2 hospitals. Methods: A retrospective chart review study was performed according to our hospital's medical records and the pediatric liver transplant database of Renji hospital. Results: A total of 767 patients received liver transplantation (LT) performed in Renji hospital between October 2006 and December 2016, of which 97 of them were admitted to PICU in our center for various complications developed after transplantation. 8.8% (16/208) and 14.4% (81/559) of patients were transferred to PICU in stages I and II, respectively, and was comparable in the 2 stages ( P = .017). The majority of patients was late postoperative children (median 185 post-LT days) in stage I. More patients were transferred to PICU directly in stage II. PICU admitted more younger (median 8.2 months) and early postoperative patients in stage II. The median length of PICU stay was 11.0 (6.0-20.5) days. The median length of mechanical ventilation was 5.0 (0.0-12.0) days. The most frequent complications were pulmonary complications (52 [53.6%] patients), surgical complications (22 [22.7%] patients), sepsis (7 [7.2%]), and other miscellaneous complications (16 [16.5%] patients). The overall 28-day PICU mortality was 25.8% (n = 25) and 64.0% (n = 16) of the deaths happened in the early postoperative period. There was significant difference concerning mortality in children with surgical complications and medical problems (54.5% [12/22] vs 17.3% [13/75], P = .001). Multivariate analysis by regression showed that the pediatric risk of mortality III score was the only independent prognostic factor ( P = .031). Conclusions: Multiple complications occur in children with LT. Although challenging, interdisciplinary cooperation between different hospitals is an effective mean to enable children to maximize the benefit gained from LT in China. |
| فهرسة مساهمة: | Keywords: PRISM III score; child; interdisciplinary cooperation; orthotopic liver transplantation; pediatric intensive care unit; risk factor |
| تواريخ الأحداث: | Date Created: 20190516 Date Completed: 20210818 Latest Revision: 20220417 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1177/0885066619849558 |
| PMID: | 31088192 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1525-1489 |
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| DOI: | 10.1177/0885066619849558 |