دورية أكاديمية
أعرض في EDS

Microbiota Alterations in Alzheimer's Disease: Involvement of the Kynurenine Pathway and Inflammation.

التفاصيل البيبلوغرافية
العنوان: Microbiota Alterations in Alzheimer's Disease: Involvement of the Kynurenine Pathway and Inflammation.
المؤلفون: Garcez ML; Neuroinflammation Group, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, 2109, Australia., Jacobs KR; Neuroinflammation Group, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, 2109, Australia., Guillemin GJ; Neuroinflammation Group, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, 2109, Australia. gilles.guillemin@mq.edu.au.
المصدر: Neurotoxicity research [Neurotox Res] 2019 Aug; Vol. 36 (2), pp. 424-436. Date of Electronic Publication: 2019 May 14.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Springer Country of Publication: United States NLM ID: 100929017 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-3524 (Electronic) Linking ISSN: 10298428 NLM ISO Abbreviation: Neurotox Res Subsets: MEDLINE
أسماء مطبوعة: Publication: <2009-> : New York : Springer
Original Publication: [Amsterdam?] : Harwood Academic Publishers,
مواضيع طبية MeSH: Alzheimer Disease/*metabolism , Gastrointestinal Microbiome/*physiology , Kynurenine/*metabolism , Signal Transduction/*physiology, Alzheimer Disease/microbiology ; Alzheimer Disease/pathology ; Animals ; Humans ; Inflammation/metabolism ; Inflammation/microbiology ; Inflammation/pathology ; Oxidative Stress/physiology
مستخلص: Alzheimer's disease (AD) is a neurodegenerative disease considered the major cause of dementia in the elderly. The main pathophysiological features of the disease are neuronal loss (mainly cholinergic neurons), glutamatergic excitotoxicity, extracellular accumulation of amyloid beta, and intracellular neurofibrillary tangles. However, other pathophysiological features of the disease have emerged including neuroinflammation and dysregulation of the kynurenine pathway (KP). The intestinal microbiota is a large and diverse collection of microorganisms that play a crucial role in regulating host health. Recently, studies have highlighted that changes in intestinal microbiota contribute to brain dysfunction in various neurological diseases including AD. Studies suggest that microbiota compositions are altered in AD patients and animal models and that these changes may increase intestinal permeability and induce inflammation. Considering that microbiota can modulate the kynurenine pathway and in turn neuroinflammation, the gut microbiome may be a valuable target for the development of new disease-modifying therapies. The present review aims to link the interactions between AD, microbiota, and the KP.
References: J Neural Transm (Vienna). 2000;107(3):343-53. (PMID: 10821443)
Adv Exp Med Biol. 2003;527:167-76. (PMID: 15206729)
Nat Rev Immunol. 2004 Oct;4(10):762-74. (PMID: 15459668)
Science. 2005 Mar 25;307(5717):1915-20. (PMID: 15790844)
J Immunol. 2005 Jul 15;175(2):1127-36. (PMID: 16002714)
Clin Chim Acta. 2006 Feb;364(1-2):91-112. (PMID: 16139826)
Appl Environ Microbiol. 1981 Dec;42(6):1103-10. (PMID: 16345902)
Cell. 2006 Feb 24;124(4):837-48. (PMID: 16497592)
Nutr Cancer. 1991;16(3-4):209-18. (PMID: 1663613)
J Neuroimmunol. 2006 Jul;176(1-2):24-33. (PMID: 16716410)
Eur J Immunol. 2007 Nov;37(11):3054-62. (PMID: 17948274)
J Immunol. 2007 Nov 15;179(10):6952-62. (PMID: 17982086)
J Neurochem. 2008 Jan;104(2):524-33. (PMID: 17986235)
Neuropsychol Rev. 2008 Mar;18(1):73-90. (PMID: 18347989)
Behav Brain Res. 2008 Sep 1;192(1):106-13. (PMID: 18359102)
Cochrane Database Syst Rev. 2008 Apr 16;(2):CD005381. (PMID: 18425918)
J Psychiatr Res. 2008 Dec;43(2):164-74. (PMID: 18456279)
Neuromolecular Med. 2008;10(4):247-58. (PMID: 18516508)
J Enzyme Inhib Med Chem. 2009 Apr;24(2):350-5. (PMID: 18608755)
Cell Transplant. 2008;17(5):559-66. (PMID: 18714675)
Cell. 2008 Nov 28;135(5):907-18. (PMID: 19041753)
Acta Neuropathol. 2009 Jul;118(1):53-69. (PMID: 19184068)
N Engl J Med. 2009 May 28;360(22):2302-9. (PMID: 19474427)
Neurobiol Aging. 2011 May;32(5):778-90. (PMID: 19482376)
PLoS One. 2009 Jul 22;4(7):e6344. (PMID: 19623258)
J Neuroinflammation. 2009 Dec 10;6:36. (PMID: 20003262)
Neurodegener Dis. 2010;7(1-3):96-8. (PMID: 20173335)
Apoptosis. 2010 Nov;15(11):1382-402. (PMID: 20213199)
Hum Mol Genet. 2010 Apr 15;19(R1):R12-20. (PMID: 20413653)
Neurobiol Aging. 2011 Mar;32(3):553.e1-11. (PMID: 20416976)
Expert Rev Neurother. 2010 May;10(5):703-10. (PMID: 20420491)
Pharmacol Res. 2010 Oct;62(4):308-17. (PMID: 20561999)
J Biol Chem. 2010 Sep 3;285(36):27601-8. (PMID: 20601425)
Redox Rep. 2010;15(4):161-8. (PMID: 20663292)
Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14691-6. (PMID: 20679230)
J Immunol. 2010 Sep 15;185(6):3190-8. (PMID: 20720200)
J Intern Med. 2011 Jan;269(1):107-17. (PMID: 20831630)
Int Immunopharmacol. 2011 Aug;11(8):932-8. (PMID: 21352963)
Bioresour Technol. 2011 Sep;102(18):8437-44. (PMID: 21429742)
J Neuroinflammation. 2011 Jul 06;8:79. (PMID: 21733175)
Nat Rev Neurosci. 2011 Jul 13;12(8):453-66. (PMID: 21750565)
Science. 2011 Oct 7;334(6052):105-8. (PMID: 21885731)
J Appl Microbiol. 2011 Dec;111(6):1297-309. (PMID: 21933312)
Science. 2011 Dec 16;334(6062):1561-5. (PMID: 22033518)
Nat Immunol. 2011 Nov 20;13(2):144-51. (PMID: 22101730)
J Immunol. 2012 Feb 1;188(3):1098-107. (PMID: 22198949)
Cold Spring Harb Perspect Med. 2011 Sep;1(1):a006189. (PMID: 22229116)
PLoS One. 2012;7(1):e30525. (PMID: 22303443)
Rejuvenation Res. 2012 Aug;15(4):395-404. (PMID: 22607625)
J Neural Transm (Vienna). 2012 Sep;119(9):1037-45. (PMID: 22622364)
Mol Psychiatry. 2013 Jun;18(6):666-73. (PMID: 22688187)
J Alzheimers Dis. 2013;33 Suppl 1:S141-4. (PMID: 22710914)
PLoS One. 2012;7(7):e42357. (PMID: 22848760)
Arch Med Res. 2012 Nov;43(8):595-9. (PMID: 23178566)
Eur Arch Psychiatry Clin Neurosci. 2013 Jun;263(4):345-52. (PMID: 23192697)
J Biol Chem. 2013 Jan 18;288(3):1548-67. (PMID: 23209301)
Neurobiol Aging. 2013 Jun;34(6):1564-80. (PMID: 23273573)
Behav Brain Res. 2013 Apr 1;242:110-6. (PMID: 23291157)
FASEB J. 2013 Apr;27(4):1711-20. (PMID: 23303207)
Neurobiol Aging. 2013 Jun;34(6):1581-8. (PMID: 23312803)
Lancet Neurol. 2013 Feb;12(2):207-16. (PMID: 23332364)
J Neuroimmunol. 2013 Mar 15;256(1-2):38-42. (PMID: 23380586)
Folia Neuropathol. 2013;51(1):1-9. (PMID: 23553131)
PLoS One. 2013 Apr 22;8(4):e59749. (PMID: 23630570)
J Neurosci Res. 2013 Sep;91(9):1133-42. (PMID: 23686642)
Mol Neurobiol. 2013 Dec;48(3):875-82. (PMID: 23686772)
Nat Commun. 2013;4:2142. (PMID: 23846752)
Cell. 2013 Jul 18;154(2):430-41. (PMID: 23870130)
Int Psychogeriatr. 2014 Jan;26(1):9-18. (PMID: 23962667)
Immunity. 2013 Aug 22;39(2):372-85. (PMID: 23973224)
Int Immunopharmacol. 2013 Nov;17(3):880-4. (PMID: 24126115)
Nat Genet. 2013 Dec;45(12):1452-8. (PMID: 24162737)
Mamm Genome. 2014 Feb;25(1-2):49-74. (PMID: 24281320)
Front Neurosci. 2014 Feb 06;8:12. (PMID: 24567701)
Annu Rev Immunol. 2014;32:403-32. (PMID: 24655296)
Hippocampus. 2014 Aug;24(8):1006-16. (PMID: 24753063)
Pharmacol Ther. 2014 Oct;144(1):1-11. (PMID: 24769081)
Annu Rev Neurosci. 2014;37:79-100. (PMID: 24821312)
Mol Endocrinol. 2014 Aug;28(8):1221-38. (PMID: 24892638)
Alzheimers Dement. 2014 Jun;10(3 Suppl):S122-45. (PMID: 24924665)
Nat Rev Immunol. 2014 Jul;14(7):463-77. (PMID: 24962261)
J Immunol. 2014 Sep 1;193(5):2157-67. (PMID: 25063874)
Nat Commun. 2014 Aug 20;5:4738. (PMID: 25141024)
Dement Geriatr Cogn Disord. 2014;38(5-6):347-65. (PMID: 25171577)
J Nanobiotechnology. 2014 Sep 02;12:33. (PMID: 25179308)
Neural Plast. 2014;2014:693851. (PMID: 25215243)
Cell. 2014 Sep 25;159(1):33-45. (PMID: 25259918)
World J Gastroenterol. 2014 Oct 21;20(39):14105-25. (PMID: 25339800)
Immune Netw. 2014 Dec;14(6):277-88. (PMID: 25550694)
Lancet Neurol. 2015 Apr;14(4):388-405. (PMID: 25792098)
Aging Dis. 2015 Mar 10;6(2):131-48. (PMID: 25821641)
J Alzheimers Dis. 2015;46(3):777-90. (PMID: 25854931)
Cell. 2015 Apr 9;161(2):264-76. (PMID: 25860609)
Cochrane Database Syst Rev. 2015 Apr 15;(4):CD006489. (PMID: 25874613)
BMC Neurol. 2015 Mar 01;15:19. (PMID: 25884176)
Cell Host Microbe. 2015 May 13;17(5):565-76. (PMID: 25974299)
J Neuroimmunol. 2015 Jun 15;283:50-7. (PMID: 26004156)
Nat Neurosci. 2015 Jul;18(7):965-77. (PMID: 26030851)
PLoS One. 2015 Aug 12;10(8):e0133666. (PMID: 26266531)
Trends Microbiol. 2015 Nov;23(11):707-718. (PMID: 26439294)
Lancet Neurol. 2015 Dec;14(12):1171-81. (PMID: 26515660)
Ageing Res Rev. 2016 Jan;25:13-23. (PMID: 26607411)
Curr Alzheimer Res. 2016;13(3):281-7. (PMID: 26679855)
Minn Med. 2016 Jan-Feb;99(1):20-1. (PMID: 26897890)
Alzheimers Dement. 2016 Mar;12(3):292-323. (PMID: 27012484)
Science. 2016 Apr 29;352(6285):544-5. (PMID: 27126037)
Brain Res. 2016 Jul 15;1643:1-9. (PMID: 27130898)
Nat Med. 2016 Jun;22(6):598-605. (PMID: 27158904)
Mikrobiologiia. 2016 Jan-Feb;85(1):3-25. (PMID: 27301124)
Cell Res. 2016 Sep;26(9):971-2. (PMID: 27339086)
Ann N Y Acad Sci. 2016 May;1372(1):53-64. (PMID: 27362360)
Neuropharmacology. 2017 Jan;112(Pt B):399-412. (PMID: 27392632)
Sci Rep. 2016 Jul 11;6:29359. (PMID: 27405597)
Genes Dev. 2016 Jul 15;30(14):1589-97. (PMID: 27474437)
Neurobiol Aging. 2017 Jan;49:60-68. (PMID: 27776263)
Front Aging Neurosci. 2016 Nov 10;8:256. (PMID: 27891089)
J Alzheimers Dis. 2017;56(1):385-390. (PMID: 27911317)
Front Cell Neurosci. 2016 Nov 23;10:269. (PMID: 27932953)
Free Radic Biol Med. 2017 Feb;103:69-86. (PMID: 28007572)
J Alzheimers Dis. 2017;56(2):775-788. (PMID: 28035935)
Nat Neurosci. 2017 Feb;20(2):145-155. (PMID: 28092661)
Sci Rep. 2017 Feb 08;7:41802. (PMID: 28176819)
PLoS Med. 2017 Mar 28;14(3):e1002270. (PMID: 28350801)
Behav Brain Res. 2017 Jul 28;331:1-13. (PMID: 28502732)
Sci Rep. 2017 May 25;7(1):2426. (PMID: 28546539)
ACS Chem Neurosci. 2017 Jul 19;8(7):1438-1447. (PMID: 28640632)
Front Aging Neurosci. 2017 Jun 20;9:195. (PMID: 28676754)
J Alzheimers Dis. 2017;59(3):815-849. (PMID: 28697569)
Science. 2017 Jul 28;357(6349):. (PMID: 28751584)
J Alzheimers Dis. 2017;60(2):495-504. (PMID: 28869479)
J Clin Diagn Res. 2017 Aug;11(8):KC01-KC05. (PMID: 28969160)
Front Immunol. 2017 Nov 06;8:1374. (PMID: 29163472)
Pharmacol Res. 2018 Apr;130:331-365. (PMID: 29458203)
Appl Physiol Nutr Metab. 2018 Jul;43(7):718-726. (PMID: 29462572)
Microb Pathog. 2018 Apr;117:285-289. (PMID: 29477743)
Trends Endocrinol Metab. 2018 May;29(5):286-288. (PMID: 29478695)
J Alzheimers Dis. 2018;63(4):1337-1346. (PMID: 29758946)
Sci Rep. 2018 May 22;8(1):8008. (PMID: 29789640)
Curr Alzheimer Res. 2018;15(12):1106-1113. (PMID: 30101706)
PLoS One. 2018 Aug 16;13(8):e0201968. (PMID: 30114226)
Dement Geriatr Cogn Disord. 2018;46(1-2):60-80. (PMID: 30145595)
Front Neurol. 2018 Aug 15;9:662. (PMID: 30158897)
Nat Commun. 2018 Sep 3;9(1):3555. (PMID: 30177845)
Curr Alzheimer Res. 2018;15(13):1179-1190. (PMID: 30182854)
Exp Gerontol. 2018 Nov;113:209-217. (PMID: 30304709)
Oxid Med Cell Longev. 2018 Nov 15;2018:4756846. (PMID: 30581532)
Oxid Med Cell Longev. 2018 Dec 9;2018:2406594. (PMID: 30622664)
Neurotox Res. 2019 Apr;35(3):530-541. (PMID: 30666558)
Nature. 1993 Jan 7;361(6407):31-9. (PMID: 8421494)
J Neurochem. 1997 Jan;68(1):280-8. (PMID: 8978736)
فهرسة مساهمة: Keywords: Alzheimer’s disease; Inflammation; Kynurenine pathway; Microbiota; Probiotics
المشرفين على المادة: 343-65-7 (Kynurenine)
تواريخ الأحداث: Date Created: 20190516 Date Completed: 20200102 Latest Revision: 20200225
رمز التحديث: 20221213
DOI: 10.1007/s12640-019-00057-3
PMID: 31089885
قاعدة البيانات: MEDLINE
الوصف
تدمد:1476-3524
DOI:10.1007/s12640-019-00057-3