دورية أكاديمية
Dendritic Cell-Derived TSLP Negatively Regulates HIF-1α and IL-1β During Dectin-1 Signaling.
العنوان: | Dendritic Cell-Derived TSLP Negatively Regulates HIF-1α and IL-1β During Dectin-1 Signaling. |
---|---|
المؤلفون: | Elder MJ; Department of Medicine, School of Clinical Medicine, Addenbrookes Hospital, University of Cambridge, Cambridge, United Kingdom.; Early Oncology R&D Division, AstraZeneca, Cambridge, United Kingdom., Webster SJ; Department of Medicine, School of Clinical Medicine, Addenbrookes Hospital, University of Cambridge, Cambridge, United Kingdom.; Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom., Fitzmaurice TJ; Department of Medicine, School of Clinical Medicine, Addenbrookes Hospital, University of Cambridge, Cambridge, United Kingdom., Shaunak ASD; Department of Medicine, School of Clinical Medicine, Addenbrookes Hospital, University of Cambridge, Cambridge, United Kingdom., Steinmetz M; Unit 970, INSERM, Paris Cardiovascular Research Center, Paris, France., Chee R; Department of Immunology, Royal Free Hospital, London, United Kingdom., Mallat Z; Division of Cardiovascular Medicine, Department of Medicine, University of Cambridge, Cambridge, United Kingdom., Cohen ES; Biopharmaceutical Research Division, AstraZeneca, Cambridge, United Kingdom., Williams DL; Department of Surgery, Center for Inflammation, Infectious Disease and Immunity, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN, United States., Gaston JSH; Department of Medicine, School of Clinical Medicine, Addenbrookes Hospital, University of Cambridge, Cambridge, United Kingdom., Goodall JC; Department of Medicine, School of Clinical Medicine, Addenbrookes Hospital, University of Cambridge, Cambridge, United Kingdom. |
المصدر: | Frontiers in immunology [Front Immunol] 2019 May 08; Vol. 10, pp. 921. Date of Electronic Publication: 2019 May 08 (Print Publication: 2019). |
نوع المنشور: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
اللغة: | English |
بيانات الدورية: | Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: [Lausanne : Frontiers Research Foundation] |
مواضيع طبية MeSH: | Cytokines/*immunology , Dendritic Cells/*immunology , Hypoxia-Inducible Factor 1, alpha Subunit/*immunology , Interleukin-1beta/*immunology , Lectins, C-Type/*immunology , Signal Transduction/*immunology, Dendritic Cells/cytology ; Humans |
مستخلص: | Thymic stromal lymphopoietin (TSLP) is a functionally pleotropic cytokine important in immune regulation, and TSLP dysregulation is associated with numerous diseases. TSLP is produced by many cell types, but has predominantly been characterized as a secreted factor from epithelial cells which activates dendritic cells (DC) that subsequently prime T helper (T |
References: | Blood. 1999 Sep 1;94(5):1561-7. (PMID: 10477681) Biochem J. 2000 Aug 15;350 Pt 1:307-12. (PMID: 10926858) J Exp Med. 2000 Sep 4;192(5):659-70. (PMID: 10974032) Nat Immunol. 2002 Jul;3(7):673-80. (PMID: 12055625) J Exp Med. 2002 Aug 5;196(3):407-12. (PMID: 12163569) FASEB J. 2003 Nov;17(14):2115-7. (PMID: 12958148) Nat Immunol. 2004 Apr;5(4):426-34. (PMID: 14991051) Blood. 2005 Oct 1;106(7):2543-50. (PMID: 15956283) Nat Immunol. 2005 Oct;6(10):1047-53. (PMID: 16142237) J Exp Med. 2005 Nov 7;202(9):1213-23. (PMID: 16275760) Nature. 2006 Mar 9;440(7081):228-32. (PMID: 16407890) J Infect Dis. 2006 May 15;193(10):1419-26. (PMID: 16619190) Nat Immunol. 2007 Jan;8(1):31-8. (PMID: 17159984) Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):914-9. (PMID: 17213320) Carbohydr Res. 1991 Oct 14;219:203-13. (PMID: 1804535) Mol Cell Biol. 2008 Aug;28(16):5106-19. (PMID: 18559422) Nat Immunol. 2008 Aug;9(8):847-56. (PMID: 18604214) J Exp Med. 2009 Mar 16;206(3):655-67. (PMID: 19273626) Nature. 2009 May 21;459(7245):433-6. (PMID: 19339971) Cell Host Microbe. 2009 May 8;5(5):487-97. (PMID: 19454352) Gut. 2009 Nov;58(11):1481-9. (PMID: 19570762) Immunol Rev. 2009 Jul;230(1):38-50. (PMID: 19594628) Sci Signal. 2010 Jan 19;3(105):ra4. (PMID: 20086239) Nat Immunol. 2010 Apr;11(4):289-93. (PMID: 20300138) Blood. 2010 Jun 10;115(23):4742-9. (PMID: 20351312) Proc Natl Acad Sci U S A. 2010 Oct 12;107(41):17698-703. (PMID: 20876114) Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19455-60. (PMID: 20974963) Eur J Immunol. 2011 Aug;41(8):2260-8. (PMID: 21681738) J Immunol. 2011 Aug 1;187(3):1207-11. (PMID: 21690322) Mucosal Immunol. 2012 Mar;5(2):184-93. (PMID: 22236997) Nat Immunol. 2012 Jan 22;13(3):246-54. (PMID: 22267217) Nature. 2012 Apr 26;484(7395):514-8. (PMID: 22466287) Eur J Immunol. 2012 Jul;42(7):1735-43. (PMID: 22585305) Hum Reprod. 2012 Oct;27(10):3028-35. (PMID: 22888172) Nat Immunol. 2013 Apr;14(4):364-71. (PMID: 23435120) Nature. 2013 Apr 11;496(7444):238-42. (PMID: 23535595) Nat Rev Immunol. 2013 Jun;13(6):397-411. (PMID: 23702978) Arthritis Res Ther. 2013;15(3):R64. (PMID: 23718630) Immunity. 2013 Jun 27;38(6):1142-53. (PMID: 23809161) Cell. 2013 Oct 10;155(2):285-95. (PMID: 24094650) J Biol Chem. 2014 Feb 7;289(6):3432-43. (PMID: 24344127) J Allergy Clin Immunol. 2014 Aug;134(2):373-81. (PMID: 24910175) J Immunol. 2014 Sep 1;193(5):2519-2530. (PMID: 25063877) Science. 2014 Sep 26;345(6204):1250684. (PMID: 25258083) J Immunol. 2015 Feb 1;194(3):1372-80. (PMID: 25539812) J Allergy Clin Immunol. 2015 Nov;136(5):1355-68.e1-15. (PMID: 25865351) Eur J Immunol. 2016 Feb;46(2):455-63. (PMID: 26573878) J Allergy Clin Immunol. 2016 Jul;138(1):150-161.e13. (PMID: 26993035) Front Immunol. 2017 Jul 07;8:791. (PMID: 28736555) Front Immunol. 2017 Jul 14;8:803. (PMID: 28769924) N Engl J Med. 2017 Sep 7;377(10):936-946. (PMID: 28877011) Eur J Immunol. 1988 Jul;18(7):1143-6. (PMID: 3261247) Exp Hematol. 1994 Mar;22(3):321-8. (PMID: 8112430) |
معلومات مُعتمدة: | G1001765 United Kingdom MRC_ Medical Research Council; RG/15/11/31593 United Kingdom BHF_ British Heart Foundation; 19639 United Kingdom VAC_ Versus Arthritis; MR/M020134/1 United Kingdom MRC_ Medical Research Council; R01 GM053522 United States GM NIGMS NIH HHS; R01 GM119197 United States GM NIGMS NIH HHS; R01 GM083016 United States GM NIGMS NIH HHS; C06 RR030655 United States RR NCRR NIH HHS |
فهرسة مساهمة: | Keywords: HIF-1α; IL-1β; ROS; Syk; TSLP; dectin-1; hypoxia |
المشرفين على المادة: | 0 (CLEC7A protein, human) 0 (Cytokines) 0 (HIF1A protein, human) 0 (Hypoxia-Inducible Factor 1, alpha Subunit) 0 (IL1B protein, human) 0 (Interleukin-1beta) 0 (Lectins, C-Type) 0 (TSLP protein, human) |
تواريخ الأحداث: | Date Created: 20190530 Date Completed: 20200924 Latest Revision: 20230201 |
رمز التحديث: | 20231215 |
مُعرف محوري في PubMed: | PMC6519317 |
DOI: | 10.3389/fimmu.2019.00921 |
PMID: | 31139177 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1664-3224 |
---|---|
DOI: | 10.3389/fimmu.2019.00921 |