دورية أكاديمية
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Repeated Working Memory Training Improves Task Performance and Neural Efficiency in Multiple Sclerosis Patients and Healthy Controls.

التفاصيل البيبلوغرافية
العنوان: Repeated Working Memory Training Improves Task Performance and Neural Efficiency in Multiple Sclerosis Patients and Healthy Controls.
المؤلفون: Aguirre N; Universitat Jaume I. Departament de Psicología Bàsica, Clínica i Psicobiología, Castelló de la Plana 12006, Spain., Cruz-Gómez ÁJ; Universitat Jaume I. Departament de Psicología Bàsica, Clínica i Psicobiología, Castelló de la Plana 12006, Spain., Miró-Padilla A; Universitat Jaume I. Departament de Psicología Bàsica, Clínica i Psicobiología, Castelló de la Plana 12006, Spain., Bueichekú E; Universitat Jaume I. Departament de Psicología Bàsica, Clínica i Psicobiología, Castelló de la Plana 12006, Spain., Broseta Torres R; ERESA, Grupo Médico., Valencia 46015, Spain., Ávila C; Universitat Jaume I. Departament de Psicología Bàsica, Clínica i Psicobiología, Castelló de la Plana 12006, Spain., Sanchis-Segura C; Universitat Jaume I. Departament de Psicología Bàsica, Clínica i Psicobiología, Castelló de la Plana 12006, Spain., Forn C; Universitat Jaume I. Departament de Psicología Bàsica, Clínica i Psicobiología, Castelló de la Plana 12006, Spain.
المصدر: Multiple sclerosis international [Mult Scler Int] 2019 Apr 16; Vol. 2019, pp. 2657902. Date of Electronic Publication: 2019 Apr 16 (Print Publication: 2019).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Hindawi Pub. Corp Country of Publication: Egypt NLM ID: 101566861 Publication Model: eCollection Cited Medium: Print ISSN: 2090-2654 (Print) Linking ISSN: 20902654 NLM ISO Abbreviation: Mult Scler Int Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Cairo : Hindawi Pub. Corp.
مستخلص: Background/objective: To explore the effectiveness of a specific working memory (WM) training program in MS patients and healthy controls (HC).
Method: 29 MS patients and 29 matched HC were enrolled in the study. MS and HC were randomly split into two groups: nontraining groups (15HC/14 MS) and training groups (14 HC/15 MS). Training groups underwent adaptive n-back training (60 min/day; 4 days). Functional magnetic resonance imaging (fMRI) was used to monitor brain activity during n-back performance (conditions: 0-back, 2-back, and 3-back) at 3 time points: (1) baseline, (2) post-training (+7days), and (3) follow-up (+35days).
Results: In post-training and follow-up fMRI sessions, trained groups (HC and MS patients) exhibited significant reaction time (RT) reductions and increases in Correct Responses (CRs) during 2-back and 3-back performance. This improvement of task performance was accompanied by a decrease in brain activation in the WM frontoparietal network. The two effects were significantly correlated.
Conclusions: After WM training, both cognitively preserved MS patients and HC participants showed task performance improvement made possible by neuroplastic processes that enhanced neural efficiency.
References: Hum Brain Mapp. 2013 Dec;34(12):3204-15. (PMID: 22711376)
Neurorehabil Neural Repair. 2013 May;27(4):284-95. (PMID: 23192417)
J Clin Exp Neuropsychol. 2013;35(2):180-91. (PMID: 23350959)
Brain Cogn. 2013 Jul;82(2):152-60. (PMID: 23660436)
J Neurol. 2015 Jan;262(1):91-100. (PMID: 25308631)
Mult Scler. 2014 May;20(6):686-94. (PMID: 24072724)
Brain Imaging Behav. 2014 Sep;8(3):387-93. (PMID: 22528829)
Mult Scler Int. 2012;2012:820240. (PMID: 23125932)
Neural Plast. 2015;2015:481574. (PMID: 26064692)
Hum Brain Mapp. 2005 May;25(1):46-59. (PMID: 15846822)
Neural Plast. 2016;2016:4292585. (PMID: 28116167)
J Neurol. 2007 May;254 Suppl 2:II53-7. (PMID: 17503130)
J Clin Exp Neuropsychol. 2005 Jan;27(1):33-54. (PMID: 15814441)
Neuroimage. 2012 Feb 15;59(4):3774-83. (PMID: 22119648)
Mult Scler. 2006 Apr;12(2):187-95. (PMID: 16629422)
Mult Scler. 2011 Apr;17(4):457-67. (PMID: 21177323)
Lancet Neurol. 2008 Dec;7(12):1139-51. (PMID: 19007738)
Hum Brain Mapp. 2007 May;28(5):424-30. (PMID: 16944483)
Dev Cogn Neurosci. 2012 Feb 15;2 Suppl 1:S167-79. (PMID: 22682905)
Mult Scler. 2014 Mar;20(3):338-48. (PMID: 23828871)
Proc Natl Acad Sci U S A. 2008 May 13;105(19):6829-33. (PMID: 18443283)
Ann Neurol. 2011 Feb;69(2):292-302. (PMID: 21387374)
J Neurol Sci. 2008 Apr 15;267(1-2):100-6. (PMID: 17997417)
Front Hum Neurosci. 2012 Jun 12;6:173. (PMID: 22701418)
Brain Imaging Behav. 2019 Aug;13(4):1115-1127. (PMID: 30006860)
J Neurol Sci. 2015 Jul 15;354(1-2):1-9. (PMID: 25998261)
Neuroimage. 2004 Aug;22(4):1732-43. (PMID: 15275929)
Nat Rev Neurol. 2011 May 10;7(6):332-42. (PMID: 21556031)
Neuroimage. 2006 Jun;31(2):686-91. (PMID: 16466933)
Neurodegener Dis. 2017;17(4-5):199-207. (PMID: 28538226)
Mult Scler J Exp Transl Clin. 2018 Jan 11;4(1):2055217317747626. (PMID: 29348927)
Front Neurol. 2015 Apr 02;6:67. (PMID: 25883585)
Neurology. 2013 Dec 10;81(24):2060-1. (PMID: 24212396)
Front Hum Neurosci. 2012 Jun 06;6:166. (PMID: 22685428)
Neuropsychol Rehabil. 2013;23(2):161-81. (PMID: 22978301)
Nat Rev Neurol. 2012 Nov 5;8(11):635-46. (PMID: 22986429)
Brain Imaging Behav. 2014 Sep;8(3):394-402. (PMID: 22706694)
J Physiol Paris. 2006 Jun;99(4-6):455-62. (PMID: 16713204)
Neurorehabil Neural Repair. 2015 Jun;29(5):453-61. (PMID: 25398725)
J Neurol. 2012 Jul;259(7):1337-46. (PMID: 22237819)
Radiology. 2012 Mar;262(3):932-40. (PMID: 22357892)
Brain Cogn. 2016 Jun;105:34-45. (PMID: 27045451)
تواريخ الأحداث: Date Created: 20190530 Latest Revision: 20240716
رمز التحديث: 20240716
مُعرف محوري في PubMed: PMC6500632
DOI: 10.1155/2019/2657902
PMID: 31139470
قاعدة البيانات: MEDLINE
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