دورية أكاديمية

Mapping of local recurrence after pancreaticoduodenectomy for distal extrahepatic cholangiocarcinoma: implications for adjuvant radiotherapy.

التفاصيل البيبلوغرافية
العنوان: Mapping of local recurrence after pancreaticoduodenectomy for distal extrahepatic cholangiocarcinoma: implications for adjuvant radiotherapy.
المؤلفون: Jung W; 1 Department of Radiation Oncology, Ewha Womans University College of Medicine, Seoul, Republic of Korea., Kim K; 1 Department of Radiation Oncology, Ewha Womans University College of Medicine, Seoul, Republic of Korea., Min SK; 2 Department of Surgery, Ewha Womans University College of Medicine, Seoul, Republic of Korea., Nam EM; 3 Department of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Republic of Korea., Lee JK; 4 Department of Radiology, Ewha Womans University College of Medicine, Seoul, Republic of Korea.
المصدر: The British journal of radiology [Br J Radiol] 2019 Aug; Vol. 92 (1100), pp. 20190285. Date of Electronic Publication: 2019 Jun 14.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0373125 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1748-880X (Electronic) Linking ISSN: 00071285 NLM ISO Abbreviation: Br J Radiol
أسماء مطبوعة: Publication: January 2024- : [Oxford] : Oxford University Press
Original Publication: London, British Institute of Radiology.
مواضيع طبية MeSH: Pancreaticoduodenectomy* , Radiotherapy, Adjuvant*, Bile Duct Neoplasms/*diagnostic imaging , Cholangiocarcinoma/*diagnostic imaging , Neoplasm Recurrence, Local/*diagnostic imaging , Tomography, X-Ray Computed/*methods, Adult ; Aged ; Aged, 80 and over ; Bile Duct Neoplasms/radiotherapy ; Bile Duct Neoplasms/surgery ; Bile Ducts/diagnostic imaging ; Bile Ducts/surgery ; Cholangiocarcinoma/radiotherapy ; Cholangiocarcinoma/surgery ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies
مستخلص: Objective: To generate a map of local recurrences after pancreaticoduodenectomy (PD) for patients with distal extrahepatic cholangiocarcinoma (DEHC) and to evaluate the adequate target volume coverage encompassing the majority of local recurrences when the clinical target volume (CTV) for pancreatic cancer was applied.
Methods: We retrospectively reviewed the records of DEHC patients who underwent pancreaticoduodenectomy and had postoperative CT scans acquired between 1991 and 2015 available. The sites of local recurrence were delineated on individual CT scans, and then, mapping was manually performed onto template CT images. Coverage of each site of local recurrence was evaluated by applying the CTV defined according to Radiation Therapy Oncology Group (RTOG) consensus guidelines (CTV RTOG ) for target delineation in the postoperative treatment of pancreatic head cancer.
Results: Of the 99 patients, 36 patients had a total of 62 local relapses identifiable by postoperative CT scans; the relapses were the most frequent in the choledochojejunostomy (CJ) site, 11 sites (17.7%); para-aortic area, 10 sites (16.1%), superior mesenteric artery area, 10 sites (16.1%); and portal vein area, 9 sites (14.5%). 21 sites (33.9%) were not covered by the CTV RTOG , and the most common site of local recurrence outside the CTV RTOG was the CJ site.
Conclusion: When mapping of local relapses was evaluated according to the CTV RTOG , the choledochojejunostomy site was identified as a high-risk area of local recurrence but was insufficiently covered within the CTV RTOG . These findings may help construct a target volume for postoperative radiotherapy in DEHC.
Advances in Knowledge: Mapping local recurrences can aid in defining appropriate target volume for postoperative radiotherapy in DEHC.
References: Ann Surg. 1996 Oct;224(4):463-73; discussion 473-5. (PMID: 8857851)
BMC Cancer. 2011 Jun 24;11:267. (PMID: 21702920)
Int J Radiat Oncol Biol Phys. 2013 Dec 1;87(5):1007-15. (PMID: 24267969)
Int Surg. 1998 Apr-Jun;83(2):124-7. (PMID: 9851328)
Oncol Lett. 2019 Feb;17(2):1784-1790. (PMID: 30675238)
Ann Surg. 1999 Jan;229(1):76-83. (PMID: 9923803)
Cancer Med. 2016 Jan;5(1):88-99. (PMID: 26645826)
Int J Radiat Oncol Biol Phys. 2011 Sep 1;81(1):189-98. (PMID: 20971573)
Radiother Oncol. 2017 Nov;125(2):365-373. (PMID: 29033254)
Surgery. 2001 Jun;129(6):677-83. (PMID: 11391365)
Int J Radiat Oncol Biol Phys. 2011 Dec 1;81(5):e853-9. (PMID: 21497455)
Ann Surg. 1999 Dec;230(6):776-82; discussion 782-4. (PMID: 10615932)
Clin Transl Oncol. 2018 Aug;20(8):1011-1017. (PMID: 29256155)
J Am Coll Surg. 2017 Apr;224(4):406-413. (PMID: 28017812)
Int J Radiat Oncol Biol Phys. 2010 Jul 15;77(4):1186-90. (PMID: 19962835)
Cancer Chemother Pharmacol. 2016 May;77(5):979-85. (PMID: 27017615)
Radiat Oncol. 2018 May 8;13(1):85. (PMID: 29739420)
Hepatogastroenterology. 1998 Nov-Dec;45(24):2388-91. (PMID: 9951929)
Int J Radiat Oncol Biol Phys. 2017 Nov 15;99(4):805-811. (PMID: 29063849)
Int J Radiat Oncol Biol Phys. 2002 Oct 1;54(2):414-9. (PMID: 12243816)
J Hepatobiliary Pancreat Surg. 2000;7(2):128-34. (PMID: 10982604)
Int J Radiat Oncol Biol Phys. 2012 Jul 1;83(3):901-8. (PMID: 22483737)
Int J Radiat Oncol Biol Phys. 2007 May 1;68(1):178-82. (PMID: 17276614)
Int J Radiat Oncol Biol Phys. 2009 Jan 1;73(1):148-53. (PMID: 18805651)
Anticancer Res. 2017 Mar;37(3):955-961. (PMID: 28314252)
Ann Surg Oncol. 2008 Nov;15(11):3147-56. (PMID: 18754070)
تواريخ الأحداث: Date Created: 20190531 Date Completed: 20190730 Latest Revision: 20220409
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC6724627
DOI: 10.1259/bjr.20190285
PMID: 31145644
قاعدة البيانات: MEDLINE
الوصف
تدمد:1748-880X
DOI:10.1259/bjr.20190285