دورية أكاديمية
Portraying infective endocarditis: results of multinational ID-IRI study.
| العنوان: | Portraying infective endocarditis: results of multinational ID-IRI study. |
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| المؤلفون: | Erdem H; IDI-IRI, Ankara, Turkey. hakanerdem1969@yahoo.com., Puca E; Department of Infectious Diseases, University Hospital Center 'Mother Teresa', Tirana, Albania., Ruch Y; Department of Infectious Diseases, Strasbourg University Hospital, Nouvel Hôpital Civil, Strasbourg, France., Santos L; Infectious Diseases Department, Centro Hospitalar São João and Faculdade de Medicina da Universidade do Porto, Porto, Portugal., Ghanem-Zoubi N; Institute of Infectious Diseases, Rambam Health Care Campus, Haifa, Israel., Argemi X; Department of Infectious Diseases, Strasbourg University Hospital, Nouvel Hôpital Civil, Strasbourg, France., Hansmann Y; Department of Infectious Diseases, Strasbourg University Hospital, Nouvel Hôpital Civil, Strasbourg, France., Guner R; Ataturk Training and Research Hospital, Department of Infectious Diseases and Clinical Microbiology, Yildirim Beyazit University, Ankara, Turkey., Tonziello G; Clinical & Research Department for Infectious Diseases, National Institute for Infectious Diseases 'Lazzaro Spallanzani', IRCCS,, Via Portuense, 292, 00149, Rome, Italy., Mazzucotelli JP; Department of Cardiovascular Surgery, Strasbourg University Hospital, Nouvel Hôpital Civil, Strasbourg, France., Como N; Service of Infectious Disease, UHC, Tirana, Albania., Kose S; Department of Infectious Diseases and Clinical Microbiology, Tepecik Training and Research Hospital, Izmir, Turkey., Batirel A; Department of Infectious Diseases and Clinical Microbiology, Dr. Lutfi Kirdar Training and Research Hospital, Health Sciences University, Istanbul, Turkey., Inan A; Department of Infectious Diseases and Clinical Microbiology, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey., Tulek N; Department of Microbiology, Atilim University, School of Medicine, Ankara, Turkey., Pekok AU; Department of Infectious Diseases and Clinical Microbiology, Pendik Medical Park Hospital, Istanbul, Turkey., Khan EA; Shifa International Hospital and Shifa Tameer-e-Millat University, Islamabad, Pakistan., Iyisoy A; Department of Cardiology, Gulhane Training and Research Hospital, Health Sciences University, Ankara, Turkey., Meric-Koc M; Department of Infectious Diseases and Clinical Microbiology, Bezmialem Vakıf University School of Medicine, Istanbul, Turkey., Kaya-Kalem A; Ataturk Training and Research Hospital, Department of Infectious Diseases and Clinical Microbiology, Yildirim Beyazit University, Ankara, Turkey., Martins PP; Infectious Diseases Department, Centro Hospitalar São João and Faculdade de Medicina da Universidade do Porto, Porto, Portugal., Hasanoglu I; Ataturk Training and Research Hospital, Department of Infectious Diseases and Clinical Microbiology, Yildirim Beyazit University, Ankara, Turkey., Silva-Pinto A; Infectious Diseases Department, Centro Hospitalar São João and Faculdade de Medicina da Universidade do Porto, Porto, Portugal., Oztoprak N; Department of Infectious Diseases and Clinical Microbiology, Antalya Training and Research Hospital, Health Sciences University, Antalya, Turkey., Duro R; Infectious Diseases Department, Centro Hospitalar São João and Faculdade de Medicina da Universidade do Porto, Porto, Portugal., Almajid F; Department of Medicine, Infectious Diseases Division, King Saud University Hospital, Riyadh, Saudi Arabia., Dogan M; Department of Infectious Diseases and Clinical Microbiology, Corlu State Hospital, Tekirdag, Antalya, Turkey., Dauby N; Department of Infectious Diseases, Centre Hospitalier Universitaire Saint-Pierre, Université libre de Bruxelles (ULB), 322 rue Haute, 1000, Brussels, Belgium., Gunst JD; Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark., Tekin R; Department of Infectious Diseases and Clinical Microbiology, Dicle University Faculty of Medicine, Diyarbakır, Turkey., Konopnicki D; Department of Infectious Diseases, Centre Hospitalier Universitaire Saint-Pierre, Université libre de Bruxelles (ULB), 322 rue Haute, 1000, Brussels, Belgium., Petrosillo N; Clinical & Research Department for Infectious Diseases, National Institute for Infectious Diseases 'Lazzaro Spallanzani', IRCCS,, Via Portuense, 292, 00149, Rome, Italy., Bozkurt I; Department of Infectious Diseases and Clinical Microbiology, Ondokuz Mayis University School of Medicine, Samsun, Turkey., Wadi J; Department of Infectious Diseases, School of Medicine, The University of Jordan, Amman, Jordan., Popescu C; Dr Victor Babes Clinical Hospital of Infectious and Tropical Disease, Bucharest, Romania., Balkan II; Department of Infectious Diseases and Clinical Microbiology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey., Ozer-Balin S; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Firat University, Elazig, Turkey., Zupanc TL; Department of Infectious Diseases, UMC Ljubljana, Ljubljana, Slovenia., Cascio A; Department of Health Promotion Sciences and Mother and Child Care 'G. D'Alessandro', University of Palermo, Palermo, Italy., Dumitru IM; Clinical Infectious Diseases Hospital, Ovidius University of Constanta, Constanta, Romania., Erdem A; Department of Pathology, Kecioren Training and Research Hospital, Ankara, Turkey., Ersoz G; Department of Infectious Diseases and Clinical Microbiology, Mersin University School of Medicine, Mersin, Turkey., Tasbakan M; Department of Infectious Diseases and Clinical Microbiology, Ege University Faculty of Medicine, Izmir, Turkey., Ajamieh OA; Department of Infectious Diseases, School of Medicine, The University of Jordan, Amman, Jordan., Sirmatel F; Department of Infectious Disease and Clinical Microbiology, Izzet Baysal University School of Medicine, Bolu, Turkey., Florescu S; Dr Victor Babes Clinical Hospital of Infectious and Tropical Disease, Bucharest, Romania., Gulsun S; Department of Infectious Diseases and Clinical Microbiology, Diyarbakir Training and Research Hospital, Diyarbakir, Turkey., Ozkaya HD; Department of Infectious Diseases and Clinical Microbiology, Cigli Regional Education Hospital, Izmir, Turkey., Sari S; Department of Intensive Care Unit, Turkey Advanced Specialty Education and Research Hospital, Ankara, Turkey., Tosun S; Department of Infectious Diseases and Clinical Microbiology, Izmir Bozyaka Training and Research Hospital, Izmir, Turkey., Avci M; Department of Infectious Disease and Clinical Microbiology, Usak University School of Medicine, Usak, Turkey., Cag Y; Department of Infectious Diseases and Clinical Microbiology, Medeniyet University, Goztepe Training and Research Hospital, Istanbul, Turkey., Celebi G; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Bulent Ecevit University, Zonguldak, Turkey., Sagmak-Tartar A; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Firat University, Elazig, Turkey., Karakus S; Department of Infectious Diseases and Clinical Microbiology, Medeniyet University, Goztepe Training and Research Hospital, Istanbul, Turkey., Sener A; Department of Infectious Diseases and Clinical Microbiology, Onsekiz Mart University School of Medicine, Canakkale, Turkey., Dedej A; Department of Nephrology, American Hospital, Tirana, Albania., Oncu S; Department of Infectious Diseases and Clinical Microbiology, Adnan Menderes University School of Medicine, Aydin, Turkey., Del Vecchio RF; Department of Clinical and Molecular Biomedicine, Section of Infectious Diseases, University of Catania, Catania, Italy., Ozturk-Engin D; Department of Infectious Diseases and Clinical Microbiology, Fatih Sultan Mehmet Training and Research Hospital, Istanbul, Turkey., Agalar C; Department of Infectious Diseases and Clinical Microbiology, Fatih Sultan Mehmet Training and Research Hospital, Istanbul, Turkey. |
| المصدر: | European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology [Eur J Clin Microbiol Infect Dis] 2019 Sep; Vol. 38 (9), pp. 1753-1763. Date of Electronic Publication: 2019 Jun 11. |
| نوع المنشور: | Journal Article; Multicenter Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: Springer Country of Publication: Germany NLM ID: 8804297 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-4373 (Electronic) Linking ISSN: 09349723 NLM ISO Abbreviation: Eur J Clin Microbiol Infect Dis Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Berlin : Springer Original Publication: [Wiesbaden, Federal Republic of Germany] : Vieweg, [c1988- |
| مواضيع طبية MeSH: | Endocarditis/*epidemiology , Prosthesis-Related Infections/*epidemiology, Adolescent ; Adult ; Aged ; Aged, 80 and over ; Aortic Valve/microbiology ; Bacteria/isolation & purification ; Endocarditis/microbiology ; Endocarditis/mortality ; Endocarditis, Bacterial ; Female ; Hospital Mortality ; Humans ; Internationality ; Male ; Middle Aged ; Mitral Valve/microbiology ; Prosthesis-Related Infections/microbiology ; Staphylococcal Infections ; Viridans Streptococci ; Young Adult |
| مستخلص: | Infective endocarditis is a growing problem with many shifts due to ever-increasing comorbid illnesses, invasive procedures, and increase in the elderly. We performed this multinational study to depict definite infective endocarditis. Adult patients with definite endocarditis hospitalized between January 1, 2015, and October 1, 2018, were included from 41 hospitals in 13 countries. We included microbiological features, types and severity of the disease, complications, but excluded therapeutic parameters. A total of 867 patients were included. A total of 631 (72.8%) patients had native valve endocarditis (NVE), 214 (24.7%) patients had prosthetic valve endocarditis (PVE), 21 (2.4%) patients had pacemaker lead endocarditis, and 1 patient had catheter port endocarditis. Eighteen percent of NVE patients were hospital-acquired. PVE patients were classified as early-onset in 24.9%. A total of 385 (44.4%) patients had major embolic events, most frequently to the brain (n = 227, 26.3%). Blood cultures yielded pathogens in 766 (88.4%). In 101 (11.6%) patients, blood cultures were negative. Molecular testing of vegetations disclosed pathogens in 65 cases. Overall, 795 (91.7%) endocarditis patients had any identified pathogen. Leading pathogens (Staphylococcus aureus (n = 267, 33.6%), Streptococcus viridans (n = 149, 18.7%), enterococci (n = 128, 16.1%), coagulase-negative staphylococci (n = 92, 11.6%)) displayed substantial resistance profiles. A total of 132 (15.2%) patients had cardiac abscesses; 693 (79.9%) patients had left-sided endocarditis. Aortic (n = 394, 45.4%) and mitral valves (n = 369, 42.5%) were most frequently involved. Mortality was more common in PVE than NVE (NVE (n = 101, 16%), PVE (n = 49, 22.9%), p = 0.042). |
| References: | Eur Heart J. 2004 Dec;25(24):2243-78. (PMID: 15589643) Eur J Clin Microbiol Infect Dis. 2006 Jun;25(6):365-8. (PMID: 16767483) Eur Heart J. 2007 Jan;28(2):230-68. (PMID: 17259184) Eur Heart J. 2007 May;28(9):1155-61. (PMID: 17363448) Infect Dis Clin North Am. 2009 Sep;23(3):643-64. (PMID: 19665088) Clin Infect Dis. 2010 Jul 15;51(2):131-40. (PMID: 20540619) Ann Clin Microbiol Antimicrob. 2011 Dec 16;10:38. (PMID: 22177310) PLoS One. 2013 Dec 09;8(12):e82665. (PMID: 24349331) Int J Infect Dis. 2015 Jan;30:106-14. (PMID: 25461657) Eur Heart J. 2015 Nov 21;36(44):3075-3128. (PMID: 26320109) Circulation. 2015 Oct 13;132(15):1435-86. (PMID: 26373316) JAMA Intern Med. 2018 Apr 1;178(4):502-510. (PMID: 29459947) Clin Microbiol Infect. 2019 Feb;25(2):178-187. (PMID: 30145401) Cardiol Res. 2018 Oct;9(5):314-317. (PMID: 30344830) New Microbes New Infect. 2018 May 30;26:S43-S51. (PMID: 30402243) Tex Heart Inst J. 1995;22(1):86-91. (PMID: 7787476) |
| فهرسة مساهمة: | Keywords: Blood culture; Infective endocarditis; Native; Prosthetic; S. aureus |
| تواريخ الأحداث: | Date Created: 20190613 Date Completed: 20191219 Latest Revision: 20200225 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1007/s10096-019-03607-x |
| PMID: | 31187307 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1435-4373 |
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| DOI: | 10.1007/s10096-019-03607-x |