دورية أكاديمية

Restrictive measure for the commercialization of antimicrobials in Brazil: results achieved.

التفاصيل البيبلوغرافية
العنوان: Restrictive measure for the commercialization of antimicrobials in Brazil: results achieved.
المؤلفون: Costa JMD; Universidade Federal de Minas Gerais. Faculdade de Farmácia. Programa de Pós-Graduação em Medicamentos e Assistência Farmacêutica. Belo Horizonte, MG, Brasil., Moura CS; McGill University. Division of Clinical Epidemiology. Department of Epidemiology. Montreal, Quebec, Canada., Pádua CAM; Universidade Federal de Minas Gerais. Faculdade de Farmácia. Departamento de Farmácia Social. Belo Horizonte, MG, Brasil., Vegi ASF; McGill University. Division of Clinical Epidemiology. Department of Epidemiology. Montreal, Quebec, Canada., Magalhães SMS; Universidade Federal de Minas Gerais. Faculdade de Farmácia. Departamento de Farmácia Social. Belo Horizonte, MG, Brasil., Rodrigues MB; Universidade Federal de Minas Gerais. Faculdade de Farmácia. Departamento de Farmácia Social. Belo Horizonte, MG, Brasil., Ribeiro AQ; Universidade Federal de Viçosa. Centro de Ciências Biológicas e da Saúde. Departamento de Nutrição e Saúde. Viçosa, MG, Brasil.
المصدر: Revista de saude publica [Rev Saude Publica] 2019 Aug 19; Vol. 53, pp. 68. Date of Electronic Publication: 2019 Aug 19.
نوع المنشور: Journal Article
اللغة: English; Portuguese
بيانات الدورية: Publisher: Universidade De Sao Paulo. Faculdade De Higiene E Saude Publica Country of Publication: Brazil NLM ID: 0135043 Publication Model: Electronic Cited Medium: Internet ISSN: 1518-8787 (Electronic) Linking ISSN: 00348910 NLM ISO Abbreviation: Rev Saude Publica Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Sao Paulo : Universidade De Sao Paulo. Faculdade De Higiene E Saude Publica
مواضيع طبية MeSH: Drug Resistance, Microbial*, Anti-Bacterial Agents/*administration & dosage , Cross Infection/*drug therapy , Cross Infection/*prevention & control , Prescription Drug Overuse/*legislation & jurisprudence, Brazil ; Cohort Studies ; Drug Monitoring ; Drug Utilization/legislation & jurisprudence ; Female ; Humans ; Infection Control/methods ; Male ; Middle Aged ; Prescription Drug Overuse/adverse effects ; Prescription Drug Overuse/statistics & numerical data ; beta-Lactamases/drug effects
مستخلص: Objective: To assess whether the incidence of hospital infection by a resistant microorganism decreased after the implementation of the restrictive measure of the National Health Surveillance Agency for the commercialization of antimicrobials.
Methods: A historical cohort study of medical records of adult patients admitted to a general and public hospital from May 2010 to July 2011. A cohort was formed with patients admitted in the period before the restrictive measure for the commercialization of antimicrobials (Phase I) and a second cohort was formed with patients admitted after the implementation of the restrictive measure (Phase II).
Results: The instantaneous risk of hospital infection by a resistant microorganism was estimated at seven by 1,000 people-time (95%CI 0.006-0.008) in Phase I, and four by 1,000 people-time (95%CI 0.003-0.005) in Phase II of the study. The differences between the survival curves in the different phases of the study and stratified by age group were also significant (p < 0.05).
Conclusions: The results suggest that the implementation of the restrictive measure of the commercialization of antimicrobials by the National Health Surveillance Agency reduced the incidence of hospital infection by a resistant microorganism.
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المشرفين على المادة: 0 (Anti-Bacterial Agents)
EC 3.5.2.6 (beta-Lactamases)
تواريخ الأحداث: Date Created: 20190822 Date Completed: 20190909 Latest Revision: 20240719
رمز التحديث: 20240719
مُعرف محوري في PubMed: PMC6705550
DOI: 10.11606/s1518-8787.2019053000879
PMID: 31432930
قاعدة البيانات: MEDLINE
الوصف
تدمد:1518-8787
DOI:10.11606/s1518-8787.2019053000879