دورية أكاديمية
Restrictive measure for the commercialization of antimicrobials in Brazil: results achieved.
العنوان: | Restrictive measure for the commercialization of antimicrobials in Brazil: results achieved. |
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المؤلفون: | Costa JMD; Universidade Federal de Minas Gerais. Faculdade de Farmácia. Programa de Pós-Graduação em Medicamentos e Assistência Farmacêutica. Belo Horizonte, MG, Brasil., Moura CS; McGill University. Division of Clinical Epidemiology. Department of Epidemiology. Montreal, Quebec, Canada., Pádua CAM; Universidade Federal de Minas Gerais. Faculdade de Farmácia. Departamento de Farmácia Social. Belo Horizonte, MG, Brasil., Vegi ASF; McGill University. Division of Clinical Epidemiology. Department of Epidemiology. Montreal, Quebec, Canada., Magalhães SMS; Universidade Federal de Minas Gerais. Faculdade de Farmácia. Departamento de Farmácia Social. Belo Horizonte, MG, Brasil., Rodrigues MB; Universidade Federal de Minas Gerais. Faculdade de Farmácia. Departamento de Farmácia Social. Belo Horizonte, MG, Brasil., Ribeiro AQ; Universidade Federal de Viçosa. Centro de Ciências Biológicas e da Saúde. Departamento de Nutrição e Saúde. Viçosa, MG, Brasil. |
المصدر: | Revista de saude publica [Rev Saude Publica] 2019 Aug 19; Vol. 53, pp. 68. Date of Electronic Publication: 2019 Aug 19. |
نوع المنشور: | Journal Article |
اللغة: | English; Portuguese |
بيانات الدورية: | Publisher: Universidade De Sao Paulo. Faculdade De Higiene E Saude Publica Country of Publication: Brazil NLM ID: 0135043 Publication Model: Electronic Cited Medium: Internet ISSN: 1518-8787 (Electronic) Linking ISSN: 00348910 NLM ISO Abbreviation: Rev Saude Publica Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Sao Paulo : Universidade De Sao Paulo. Faculdade De Higiene E Saude Publica |
مواضيع طبية MeSH: | Drug Resistance, Microbial*, Anti-Bacterial Agents/*administration & dosage , Cross Infection/*drug therapy , Cross Infection/*prevention & control , Prescription Drug Overuse/*legislation & jurisprudence, Brazil ; Cohort Studies ; Drug Monitoring ; Drug Utilization/legislation & jurisprudence ; Female ; Humans ; Infection Control/methods ; Male ; Middle Aged ; Prescription Drug Overuse/adverse effects ; Prescription Drug Overuse/statistics & numerical data ; beta-Lactamases/drug effects |
مستخلص: | Objective: To assess whether the incidence of hospital infection by a resistant microorganism decreased after the implementation of the restrictive measure of the National Health Surveillance Agency for the commercialization of antimicrobials. Methods: A historical cohort study of medical records of adult patients admitted to a general and public hospital from May 2010 to July 2011. A cohort was formed with patients admitted in the period before the restrictive measure for the commercialization of antimicrobials (Phase I) and a second cohort was formed with patients admitted after the implementation of the restrictive measure (Phase II). Results: The instantaneous risk of hospital infection by a resistant microorganism was estimated at seven by 1,000 people-time (95%CI 0.006-0.008) in Phase I, and four by 1,000 people-time (95%CI 0.003-0.005) in Phase II of the study. The differences between the survival curves in the different phases of the study and stratified by age group were also significant (p < 0.05). Conclusions: The results suggest that the implementation of the restrictive measure of the commercialization of antimicrobials by the National Health Surveillance Agency reduced the incidence of hospital infection by a resistant microorganism. |
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المشرفين على المادة: | 0 (Anti-Bacterial Agents) EC 3.5.2.6 (beta-Lactamases) |
تواريخ الأحداث: | Date Created: 20190822 Date Completed: 20190909 Latest Revision: 20240719 |
رمز التحديث: | 20240719 |
مُعرف محوري في PubMed: | PMC6705550 |
DOI: | 10.11606/s1518-8787.2019053000879 |
PMID: | 31432930 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1518-8787 |
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DOI: | 10.11606/s1518-8787.2019053000879 |