دورية أكاديمية
Starch Digestion by Gut Bacteria: Crowdsourcing for Carbs.
| العنوان: | Starch Digestion by Gut Bacteria: Crowdsourcing for Carbs. |
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| المؤلفون: | Cerqueira FM; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Photenhauer AL; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Pollet RM; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Brown HA; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Koropatkin NM; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI 48109, USA. Electronic address: nkoropat@umich.edu. |
| المصدر: | Trends in microbiology [Trends Microbiol] 2020 Feb; Vol. 28 (2), pp. 95-108. Date of Electronic Publication: 2019 Oct 14. |
| نوع المنشور: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Trends Journals Country of Publication: England NLM ID: 9310916 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-4380 (Electronic) Linking ISSN: 0966842X NLM ISO Abbreviation: Trends Microbiol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Cambridge : Elsevier Trends Journals Original Publication: Cambridge, UK : Elsevier Trends Journals, c1993- |
| مواضيع طبية MeSH: | Gastrointestinal Microbiome/*physiology , Starch/*metabolism, Animals ; Butyrates/metabolism ; Colon/metabolism ; Fatty Acids, Volatile/metabolism ; Host Microbial Interactions ; Humans ; Mice ; Prebiotics |
| مستخلص: | Starch is a polymer of glucose and is one of the most abundant carbohydrates in a Western diet. Resistant starch escapes digestion by host small intestinal glucoamylases and transits the colon where it is degraded by the combined efforts of many gut bacteria. Bacterial metabolism and fermentation of resistant starch leads to increases in short-chain fatty acids, including the clinically beneficial butyrate. Here, we review the molecular machinery that gut bacteria use to degrade starch and how these functions may intersect to facilitate complete starch digestion. While the protein complexes that gut bacteria use to degrade starch differ across phyla, some molecular details converge to promote the optimal positioning of enzymes and substrate for starch degradation. (Copyright © 2019 Elsevier Ltd. All rights reserved.) |
| فهرسة مساهمة: | Keywords: GH13; amylase; gut microbiota; prebiotics; pullulanase; starch |
| المشرفين على المادة: | 0 (Butyrates) 0 (Fatty Acids, Volatile) 0 (Prebiotics) 9005-25-8 (Starch) |
| تواريخ الأحداث: | Date Created: 20191019 Date Completed: 20210604 Latest Revision: 20210604 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1016/j.tim.2019.09.004 |
| PMID: | 31624005 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1878-4380 |
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| DOI: | 10.1016/j.tim.2019.09.004 |