دورية أكاديمية
If you play with fire, you may get burned.
| العنوان: | If you play with fire, you may get burned. |
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| المؤلفون: | Segura J; Integrative Pharmacology and Systems Neuroscience Research Group, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.; Catalonian Antidoping Laboratory, Doping Control Research Group, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain., Ventura R; Catalonian Antidoping Laboratory, Doping Control Research Group, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain., Pascual JA; Integrative Pharmacology and Systems Neuroscience Research Group, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain., de la Torre R; Integrative Pharmacology and Systems Neuroscience Research Group, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain. |
| المصدر: | Drug testing and analysis [Drug Test Anal] 2020 May; Vol. 12 (5), pp. 582-587. Date of Electronic Publication: 2020 Jan 24. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: John Wiley & Sons Country of Publication: England NLM ID: 101483449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1942-7611 (Electronic) Linking ISSN: 19427603 NLM ISO Abbreviation: Drug Test Anal Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Chichester, UK : John Wiley & Sons |
| مواضيع طبية MeSH: | Alcoholic Beverages/*analysis , Doping in Sports/*methods , Gas Chromatography-Mass Spectrometry/*methods , Urine/*chemistry, Anabolic Agents/urine ; Humans ; Substance Abuse Detection/methods |
| مستخلص: | This article reports an interesting doping case in the late 1990s involving the physical tampering of a urine sample containing a prohibited substance, by adding an alcoholic beverage. The regulations and knowledge available at that time allowed consideration of the case as a sanctioned manipulation and the prohibited substance as an additional element that explained the reasons for it. The development of the case involved some aspects that appeared for the first time in doping control. These include, among others, the participation of an enologist as part of the B sample confirmation, forensic inspection of the sample container, the early development of gas chromatography/combustion/isotopic ratio mass spectrometry (GC/C/IRMS), and the first public hearing by the Court of Arbitration for Sport (CAS), which allowed a wide following of the developments of the case. The information was especially interesting for the general public as the athlete had had, at that time, great Olympic success. (© 2019 John Wiley & Sons, Ltd.) |
| References: | Baselt RC, Cravey RH. Disposition of Toxic Drugs and Chemicals in Man. 4th ed. Foster City, CA: Chemical Toxicology Institute; 1994:293-296. Detection of illegal drugs by Isotope Ratio Mass Spectrometry: improvement of sensitivity, widening of applicability and development of tests and reference data (ISOTRACE). European Commission (project G6RD CT99 00149). FINA Doping Panel Judgement 7/98, August 1998. CAS Arbitral Award 98/211, June 1999. Uralets VP& Gillette PA. Anabolic steroid 4-androsten-3,17-dione: abuse and detection in urine. Presented at the Congress of the International Association of Forensic Toxicologists, Albuquerque, USA. TIAFT: Newport Beach (CA). Uralets VP & Gillette PA. Over-the-counter anabolic steroids 4-androsten-3,17-dione; 4-androste-3β,17β-diol, and 19-nor-4-androsten-3,17-dione: Excretion studies in men. In: Schanzer W et al., eds. Recent Advances in Doping Analysis. Cologne (Germany): Sport&Buch Strauβ; 1999:147-170. Van Eenoo P et al. Excretion studies with 4-androstene-3,17-dione. In: Schanzer W et al., eds. Recent Advances in Doping Analysis. Cologne (Germany):Sport&Buch Strauβ; 1999:171-180. Garle M et al. Androstenedione: Excretion studies from single and multiple dose experiments. In: Schanzer W et al., eds. Recent Advances in Doping Analysis. Cologne (Germany):Sport&Buch Strauβ; 1999:181-184. Southan G, Mallet A, Jumeau J, et al. Misuse of testosterone in sport: an approach to detection by measurement of isotopic abundance using GC-IRMS. Abstracts of the Second International Symposium on Applied Mass Spectrometry in the Health Sciences. Barcelona:Fira de Barcelona, 1990, 306. Becchi M, Aguilera R, Farizon Y, Flament MM, Casabianca H, James P. Gas chromatography/combustion/isotope-ratio mass spectrometry analysis of urinary steroids to detect misuse of testosterone in sport. Rapid Commun Mass Spectrom. 1994;8(4):304-308. Aguilera R, Becchi M, Grenot C, Casabianca H, Hatton CK. Detection of testosterone misuse: comparison of two chromatographic sample preparation methods for gas chromatographic-combustion/isotope ratio mass spectrometric analysis. J Chromatogr B Biomed Appl. 1996;687(1):43-53. Segura J, Hemmersbach P, Sonksen P. Sports Drug Testing. TRAC. 1997;16(7):VI-VII. Shackleton CH, Phillips A, Chang T, Li Y. Confirming testosterone administration by isotope ratio mass spectrometric analysis of urinary androstanediols. Steroids. 1997;62(4):379-387. |
| فهرسة مساهمة: | Keywords: CAS Public Hearing; Olympic Champion; forensic analysis; fraud; isotope ratio mass spectrometry; urine whiskey smelling |
| المشرفين على المادة: | 0 (Anabolic Agents) |
| تواريخ الأحداث: | Date Created: 20191101 Date Completed: 20210125 Latest Revision: 20210125 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1002/dta.2718 |
| PMID: | 31667995 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1942-7611 |
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| DOI: | 10.1002/dta.2718 |