دورية أكاديمية
Histogenesis and Histomorphometric study of Human Fetal Small Intestine.
| العنوان: | Histogenesis and Histomorphometric study of Human Fetal Small Intestine. |
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| المؤلفون: | Salva MN; KMC Manipal, Manipal, Manipal Academy of Higher Education, Manipal, India, 576104., Gupta C; KMC Manipal, Manipal, Manipal Academy of Higher Education, Manipal, India, 576104., Pandey AK; KMC Manipal, Manipal, Manipal Academy of Higher Education, Manipal, India, 576104., Kumar N; MCOPS, Manipal, Manipal Academy of Higher Education, Manipal, India, 576104., Kotian SR; KMC Manipal, Manipal, Manipal Academy of Higher Education, Manipal, India, 576104., Kalthur SG; KMC Manipal, Manipal, Manipal Academy of Higher Education, Manipal, India, 576104. |
| المصدر: | Ethiopian journal of health sciences [Ethiop J Health Sci] 2019 Nov; Vol. 29 (6), pp. 689-696. |
| نوع المنشور: | Comparative Study; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Research and Publications Office of Jimma University Country of Publication: Ethiopia NLM ID: 101224773 Publication Model: Print Cited Medium: Internet ISSN: 2413-7170 (Electronic) Linking ISSN: 10291857 NLM ISO Abbreviation: Ethiop J Health Sci Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Jimma, Ethiopia : Research and Publications Office of Jimma University |
| مواضيع طبية MeSH: | Fetal Development/*physiology , Fetus/*cytology , Intestine, Small/*cytology , Morphogenesis/*physiology, Age Factors ; Female ; Gestational Age ; Humans ; India ; Male ; Pregnancy |
| مستخلص: | Background: Intestine plays a major role for the normal growth of the fetus during the prenatal period. The process of the embryonic development is not quantified histologically. Therefore the main aim of the study was to measure the thickness of all part of the wall of the small intestine that are mucosa, submucosa and muscularis externa and to look for the appearance of the Brunner's glands and Peyer's patches in the submucosa of duodenum and ileum. Methods: The present study was carried out on 30 fetuses of gestational ages ranging from 11-36 weeks. Ten fetuses from each trimester were used in the study. Fetal small intestine were dissected carefully, and were separated as duodenum, jejunum & ileum and fixed in formalin solution. The tissue was processed for histology and then slides were stained with Haematoxylin and Eosin. The microscopic features were noted using light microscope. Results: The thickness of the mucosa, submucosa and the muscularis externa was observed to be increased in first trimester, decreased in the second trimester and again increased in the third trimester, which could be because of the increase cell turnover and the arrangement of the collagen fibers as to support the mucosa and the muscularis externa. Conclusion: Thus, the knowledge of the histogenesis and histomorphometry of the human fetal small intestine is crucial for the adult gastroenterologist to appreciate, because of the potential for these early life events to affect the responsiveness of the intestine to physiological or pathological challenges in later life. (©2019 Salva MN, et al.) |
| References: | Anat Anz. 1990;171(1):23-30. (PMID: 2403210) Clin Exp Immunol. 1986 Jun;64(3):536-43. (PMID: 3491695) Gut. 1965 Jun;6(3):225-9. (PMID: 18668776) World J Gastroenterol. 2010 Feb 21;16(7):787-99. (PMID: 20143457) Gastroenterology. 1976 May;70(5 PT.1):790-810. (PMID: 770227) Histol Histopathol. 2002;17(3):731-7. (PMID: 12168781) Anat Rec A Discov Mol Cell Evol Biol. 2004 Jun;278(2):540-50. (PMID: 15164342) |
| فهرسة مساهمة: | Keywords: Brunner's gland; Peyer's patches; Small intestine; Thickness |
| تواريخ الأحداث: | Date Created: 20191120 Date Completed: 20200408 Latest Revision: 20220411 |
| رمز التحديث: | 20221213 |
| مُعرف محوري في PubMed: | PMC6842717 |
| DOI: | 10.4314/ejhs.v29i6.5 |
| PMID: | 31741639 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2413-7170 |
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| DOI: | 10.4314/ejhs.v29i6.5 |