دورية أكاديمية
أعرض في EDS

Fibroin-Gelatin Composite Stimulates the Regeneration of a Splinted Full-Thickness Skin Wound in Mice.

التفاصيل البيبلوغرافية
العنوان: Fibroin-Gelatin Composite Stimulates the Regeneration of a Splinted Full-Thickness Skin Wound in Mice.
المؤلفون: Arkhipova AY; M. V. Lomonosov Moscow State University, Moscow, Russia. anastasia-yu.arkhipova@yandex.ru.; M. F. Vladimirsky Moscow Regional Research and Clinical Institute, Moscow, Russia. anastasia-yu.arkhipova@yandex.ru., Kulikov DA; M. F. Vladimirsky Moscow Regional Research and Clinical Institute, Moscow, Russia., Moisenovich AM; M. V. Lomonosov Moscow State University, Moscow, Russia., Andryukhina VV; M. F. Vladimirsky Moscow Regional Research and Clinical Institute, Moscow, Russia., Chursinova YV; M. F. Vladimirsky Moscow Regional Research and Clinical Institute, Moscow, Russia., Filyushkin YN; M. F. Vladimirsky Moscow Regional Research and Clinical Institute, Moscow, Russia., Fedulov AV; M. F. Vladimirsky Moscow Regional Research and Clinical Institute, Moscow, Russia., Bobrov MA; M. F. Vladimirsky Moscow Regional Research and Clinical Institute, Moscow, Russia., Mosalskaya DV; M. F. Vladimirsky Moscow Regional Research and Clinical Institute, Moscow, Russia., Glazkova PA; M. F. Vladimirsky Moscow Regional Research and Clinical Institute, Moscow, Russia., Kulikov AV; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Moscow, Russia., Nalivkin AE; M. F. Vladimirsky Moscow Regional Research and Clinical Institute, Moscow, Russia., Molochkov AV; M. F. Vladimirsky Moscow Regional Research and Clinical Institute, Moscow, Russia., Semenov DY; M. F. Vladimirsky Moscow Regional Research and Clinical Institute, Moscow, Russia.
المصدر: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2019 Nov; Vol. 168 (1), pp. 95-98. Date of Electronic Publication: 2019 Nov 22.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Springer Country of Publication: United States NLM ID: 0372557 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-8221 (Electronic) Linking ISSN: 00074888 NLM ISO Abbreviation: Bull Exp Biol Med Subsets: MEDLINE
أسماء مطبوعة: Publication: New York : Springer
Original Publication: New York, Consultants Bureau.
مواضيع طبية MeSH: Fibroins/*chemistry , Fibroins/*pharmacology , Gelatin/*chemistry , Gelatin/*pharmacology , Skin/*metabolism , Skin Diseases/*drug therapy, Animals ; Male ; Mice ; Mice, Inbred C57BL ; Regeneration/drug effects ; Skin/drug effects ; Wound Healing/drug effects
مستخلص: The effects of composite fibroin-gelatin microparticles (100-250 μ) on the rate of wound healing and regeneration under conditions of contraction prevention were studied on the model of splinted full-thickness skin wound in a mouse. Subcutaneous injection of these particles into the defect area accelerated wound healing and promoted re-epithelialization and recovery of normal structure of the epidermis. In addition, the composite microparticles promoted the formation of connective tissue of characteristic structure, replacing the derma over the entire defect, and stimulated regeneration of subcutaneous muscle (panniculus carnosus) and skin appendages (sebaceous glands and hair follicles).
فهرسة مساهمة: Keywords: fibroin; gelatin; regeneration; splinted full-thickness skin wound in mouse
المشرفين على المادة: 9000-70-8 (Gelatin)
9007-76-5 (Fibroins)
تواريخ الأحداث: Date Created: 20191124 Date Completed: 20200420 Latest Revision: 20200420
رمز التحديث: 20240829
DOI: 10.1007/s10517-019-04656-0
PMID: 31758379
قاعدة البيانات: MEDLINE
الوصف
تدمد:1573-8221
DOI:10.1007/s10517-019-04656-0