دورية أكاديمية
Effect of an intensive lifestyle intervention on the prevalence of metabolic syndrome and its components among overweight and obese adults.
| العنوان: | Effect of an intensive lifestyle intervention on the prevalence of metabolic syndrome and its components among overweight and obese adults. |
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| المؤلفون: | Guzmán M; Division of Research & Development, Department of Medical Affairs, Medi-Weightloss, 509 South Hyde Park Avenue, Tampa, FL 33606, USA., Zbella E; Florida Fertility Institute, 2454 N. McMullen Booth Road Suite 601, Clearwater, FL 33759, USA., Alvarez SS; Department of Medical Affairs, Medi-Weightloss, 509 South Hyde Park Avenue, Tampa, FL 33606, USA., Nguyen JL; Department of Pharmacy Practice, College of Pharmacy, Mercer University, 3001 Mercer University Drive, Atlanta, GA 30341, USA., Imperial E; Iredell Primary Care for Women, 114 Gateway Blvd, Suite B, Mooresville, NC 28117, USA., Troncale FJ; Section of Gastroenterology, Yale University School of Medicine, 333 Cedar St, New Haven, CT 06510, USA., Holub C; Department of Public Health, College of Education, Health and Human Services, California State University, 333 S. Twin Oaks Valley Road, San Marcos, CA 92096, USA., Mallhi AK; Division of Research & Development, Department of Medical Affairs, Medi-Weightloss, 509 South Hyde Park Avenue, Tampa, FL 33606, USA., VanWyk S; Independent Consultant, 2518 69th Ave S, St. Petersburg, FL 33712, USA. |
| المصدر: | Journal of public health (Oxford, England) [J Public Health (Oxf)] 2020 Nov 23; Vol. 42 (4), pp. 828-838. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Oxford University Press Country of Publication: England NLM ID: 101188638 Publication Model: Print Cited Medium: Internet ISSN: 1741-3850 (Electronic) Linking ISSN: 17413842 NLM ISO Abbreviation: J Public Health (Oxf) Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Oxford, UK : Oxford University Press, c2004- |
| مواضيع طبية MeSH: | Metabolic Syndrome*/epidemiology , Metabolic Syndrome*/therapy, Adult ; Humans ; Life Style ; Longitudinal Studies ; Obesity/epidemiology ; Obesity/therapy ; Overweight/epidemiology ; Overweight/therapy ; Prevalence ; Prospective Studies ; Risk Factors |
| مستخلص: | Background: Despite the fact that up to a third of the global population has metabolic syndrome (MetS), it has been overlooked in clinical settings. This study assesses the impact of a physician-supervised nonsurgical weight management program on the prevalence of MetS and its key indicators. Methods: Four-hundred seventy-nine overweight and obese participants aged 19 years or older were included in a prospective longitudinal study. Changes in MetS and its key indicators were assessed using the binomial exact, chi-square and Wilcoxon signed-rank tests in an intent-to-treat study population. Differences in age strata were assessed using a generalized linear model. Results: Fifty-two percent of participants (n = 249) had MetS at baseline. Prevalence of MetS decreased steadily with significant changes from baseline observed at weeks 13 (31.8%, P < 0.0001), 26 (28.7%, P < 0.0012) and 39 (21.6%, P < 0.0002); changes from baseline were observed at week 52 as statistically significant (16.7%, P < 0.0012). Improvements in anthropometrics and levels of key indicators of MetS were observed throughout the study. Conclusion: These findings confirm that weight loss is inversely associated with prevalence of MetS and its key indicators among overweight and obese individuals. Future studies may benefit from a larger sample size and better retention (ClinicalTrials.gov ID: NCT03588117). (© The Author(s) 2019. Published by Oxford University Press on behalf of Faculty of Public Health.) |
| References: | Int J Obes (Lond). 2012 Apr;36(4):614-24. (PMID: 21673653) Am J Clin Nutr. 1992 Aug;56(2):320-8. (PMID: 1386186) BMJ Open Diabetes Res Care. 2017 Feb 20;5(1):e000341. (PMID: 28316795) J Clin Invest. 1981 May;67(5):1425-30. (PMID: 7229033) Diabetes Care. 2004 Jul;27(7):1570-6. (PMID: 15220230) Obes Res. 2005 Mar;13(3):608-14. (PMID: 15833947) Prev Chronic Dis. 2017 Mar 16;14:E24. (PMID: 28301314) Diabetes Care. 2001 Oct;24(10):1758-63. (PMID: 11574438) Diabetes Obes Metab. 2002 Nov;4(6):407-14. (PMID: 12406040) Circulation. 2005 Oct 25;112(17):2735-52. (PMID: 16157765) Diabetes Care. 1999 Dec;22(12):1999-2003. (PMID: 10587833) Arterioscler Thromb Vasc Biol. 2008 Jun;28(6):1039-49. (PMID: 18356555) Arch Intern Med. 2003 Feb 24;163(4):427-36. (PMID: 12588201) Natl Health Stat Report. 2009 May 5;(13):1-7. (PMID: 19634296) Public Health Nutr. 2015 Jan;18(1):122-9. (PMID: 24468205) J Lipid Res. 1993 Dec;34(12):2183-91. (PMID: 8301237) J Korean Med Sci. 2012 Sep;27(9):1057-61. (PMID: 22969252) Arteriosclerosis. 1984 Mar-Apr;4(2):115-23. (PMID: 6422916) J Am Coll Cardiol. 2014 Jul 1;63(25 Pt B):2985-3023. (PMID: 24239920) Diabetes Care. 2011 Jul;34(7):1481-6. (PMID: 21593294) J Clin Endocrinol Metab. 2012 Jul;97(7):2482-8. (PMID: 22508708) Arterioscler Thromb Vasc Biol. 2008 Apr;28(4):629-36. (PMID: 18174459) |
| فهرسة مساهمة: | Keywords: chronic disease; obesity |
| سلسلة جزيئية: | ClinicalTrials.gov NCT03588117 |
| تواريخ الأحداث: | Date Created: 20191217 Date Completed: 20210625 Latest Revision: 20210625 |
| رمز التحديث: | 20221213 |
| مُعرف محوري في PubMed: | PMC7685849 |
| DOI: | 10.1093/pubmed/fdz170 |
| PMID: | 31840755 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1741-3850 |
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| DOI: | 10.1093/pubmed/fdz170 |