التفاصيل البيبلوغرافية
| العنوان: |
Mechanisms linking bovine viral diarrhea virus (BVDV) infection with infertility in cattle. |
| المؤلفون: |
Oguejiofor CF; Department of Veterinary Obstetrics and Reproductive Diseases, University of Nigeria, Nsukka410001, Nigeria.; Department of Pathobiology and Population Sciences, Royal Veterinary College, North Mymms, Hatfield, HertfordshireAL9 7TA, UK., Thomas C; Department of Pathobiology and Population Sciences, Royal Veterinary College, North Mymms, Hatfield, HertfordshireAL9 7TA, UK., Cheng Z; Department of Pathobiology and Population Sciences, Royal Veterinary College, North Mymms, Hatfield, HertfordshireAL9 7TA, UK., Wathes DC; Department of Pathobiology and Population Sciences, Royal Veterinary College, North Mymms, Hatfield, HertfordshireAL9 7TA, UK. |
| المصدر: |
Animal health research reviews [Anim Health Res Rev] 2019 Jun; Vol. 20 (1), pp. 72-85. Date of Electronic Publication: 2019 Sep 09. |
| نوع المنشور: |
Journal Article; Research Support, Non-U.S. Gov't; Review |
| اللغة: |
English |
| بيانات الدورية: |
Publisher: CABI Pub Country of Publication: England NLM ID: 101083072 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1475-2654 (Electronic) Linking ISSN: 14662523 NLM ISO Abbreviation: Anim Health Res Rev Subsets: MEDLINE |
| أسماء مطبوعة: |
Original Publication: Wallingford, UK ; New York : CABI Pub., c2000- |
| مواضيع طبية MeSH: |
Abortion, Veterinary/*virology , Bovine Virus Diarrhea-Mucosal Disease/*complications , Infertility/*veterinary , Pregnancy Complications, Infectious/*veterinary, Animals ; Bovine Virus Diarrhea-Mucosal Disease/immunology ; Cattle ; Diarrhea Viruses, Bovine Viral/immunology ; Female ; Infertility/virology ; Pregnancy ; Pregnancy Complications, Infectious/virology |
| مستخلص: |
Bovine viral diarrhea virus (BVDV) is an important infectious disease agent that causes significant reproductive and economic losses in the cattle industry worldwide. Although BVDV infection is known to cause poor fertility in cattle, a greater part of the underlying mechanisms particularly associated with early reproductive losses are not clearly understood. Previous studies reported viral compromise of reproductive function in infected bulls. In females, BVDV infection is thought to be capable of killing the oocyte, embryo or fetus directly, or to induce lesions that result in fetal abortion or malformation. BVDV infections may also induce immune dysfunction, and predispose cattle to other diseases that cause poor health and fertility. Other reports also suggested BVDV-induced disruption of the reproductive endocrine system, and a disruption of leukocyte and cytokine functions in the reproductive organs. More recent studies have provided evidence of viral-induced suppression of endometrial innate immunity that may predispose to uterine disease. Furthermore, there is new evidence that BVDV may potentially disrupt the maternal recognition of pregnancy or the immune protection of the conceptus. This review brings together the previous reports with the more recent findings, and attempts to explain some of the mechanisms linking this important virus to infertility in cattle. |
| فهرسة مساهمة: |
Keywords: Bovine viral diarrhea virus; immunity; infertility; pregnancy; reproduction |
| تواريخ الأحداث: |
Date Created: 20200103 Date Completed: 20200512 Latest Revision: 20200512 |
| رمز التحديث: |
20231215 |
| DOI: |
10.1017/S1466252319000057 |
| PMID: |
31895016 |
| قاعدة البيانات: |
MEDLINE |
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