دورية أكاديمية

Effect of a Supplementation with Two Quelites on Urinary Excretion of Arsenic in Adolescents Exposed to Water Contaminated with the Metalloid in a Community in the State of Guanajuato, Mexico.

التفاصيل البيبلوغرافية
العنوان: Effect of a Supplementation with Two Quelites on Urinary Excretion of Arsenic in Adolescents Exposed to Water Contaminated with the Metalloid in a Community in the State of Guanajuato, Mexico.
المؤلفون: Santiago-Saenz YO; Área Académica de Ingeniería Agroindustrial e Ingeniería en Alimentos, Instituto de Ciencias Agropecuarias, Universidad Autónoma del Estado de Hidalgo, Tulancingo 43600, Mexico., Monroy-Torres R; Departamento de Medicina y Nutrición, División de Ciencias de la Salud, Universidad de Guanajuato, León 37670, Mexico., Rocha-Amador DO; Departamento de Farmacia, División de Ciencias Naturales y Exactas, Universidad de Guanajuato, Guanajuato 36050, Mexico., Hernández-Fuentes AD; Área Académica de Ingeniería Agroindustrial e Ingeniería en Alimentos, Instituto de Ciencias Agropecuarias, Universidad Autónoma del Estado de Hidalgo, Tulancingo 43600, Mexico.
المصدر: Nutrients [Nutrients] 2019 Dec 30; Vol. 12 (1). Date of Electronic Publication: 2019 Dec 30.
نوع المنشور: Clinical Trial; Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI Publishing
مواضيع طبية MeSH: Chenopodium* , Dietary Supplements* , Portulaca*, Arsenic/*urine , Water Pollutants, Chemical/*urine, Child ; Diet ; Drinking Water/chemistry ; Female ; Humans ; Male ; Mexico ; Plants, Edible
مستخلص: Quelites are Mexican wild plants, reported as excellent sources of nutritional compounds such as amino acids (serine, glycine, and cysteine), minerals (Mg, Fe, and Zn), and phytochemicals, as phenolic acids (chlorogenic acid) and flavonoids (phloridzin and naringenin); on the other hand, high biological activity has been shown in these compounds. This work aimed to evaluate the effect of a supplementation with two endemic quelites of Mexico ( Chenopodium berlandieri L. and Portulaca Oleracea L.); in addition to supplementation, a nutritional intervention was performed; the biomarkers of hemoglobin (Hb), urinary malondialdehyde (UMDA), and urinary arsenic (UAs) were measured in adolescents exposed to arsenic. A clinical intervention study was conducted in 27 adolescents ages 11 to 12 years for 4 weeks. Weekly anthropometric and dietary evaluations were carried out, as well as the concentration of Hb; the UMDA and UAs were performed by plate-based colorimetric measurement and atomic absorption spectrophotometry with the hydrides generation system, respectively. The results showed that UMDA concentrations had a significant improvement in the supplemented group (SG) vs. control group (CG) (SG = 1.59 ± 0.89 µM/g creatinine vs. CG = 2.90 ± 0.56 µM/g creatinine) in the second week of intervention; on the other hand, the supplemented group showed an increase in Hb levels (15.12 ± 0.99 g/dL) in the same week; finally after the second week, an increase in UAs levels was observed significantly compared to the baseline value (Baseline: 56.85; Week 2: 2.02 µg/g creatinine). Therefore, the results show that the mixture of quelites (a rich source of phytochemicals and nutrients) improved hemoglobin and UMDA levels, and urinary arsenic excretion from the second week in the exposed population.
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فهرسة مساهمة: Keywords: arsenic; quelites; supplementation
المشرفين على المادة: 0 (Drinking Water)
0 (Water Pollutants, Chemical)
N712M78A8G (Arsenic)
تواريخ الأحداث: Date Created: 20200108 Date Completed: 20200909 Latest Revision: 20240328
رمز التحديث: 20240329
مُعرف محوري في PubMed: PMC7019896
DOI: 10.3390/nu12010098
PMID: 31905888
قاعدة البيانات: MEDLINE
الوصف
تدمد:2072-6643
DOI:10.3390/nu12010098