دورية أكاديمية
أعرض في EDS

Timing of intraventricular infusion test for diagnosing idiopathic normal pressure hydrocephalus.

التفاصيل البيبلوغرافية
العنوان: Timing of intraventricular infusion test for diagnosing idiopathic normal pressure hydrocephalus.
المؤلفون: Andreasen TH; Department of Neurosurgery, Copenhagen University Hospital Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark. trinehjorslev@hotmail.com., Lilja-Cyron A; Department of Neurosurgery, Copenhagen University Hospital Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark., Holst AV; Department of Neurosurgery, Copenhagen University Hospital Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark., Christoffersen D; Department of Neurosurgery, Copenhagen University Hospital Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark., Johnsen SD; Department of Neurosurgery, Copenhagen University Hospital Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark., Juhler M; Department of Neurosurgery, Copenhagen University Hospital Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.
المصدر: Acta neurochirurgica [Acta Neurochir (Wien)] 2020 May; Vol. 162 (5), pp. 1011-1017. Date of Electronic Publication: 2020 Jan 07.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Springer Country of Publication: Austria NLM ID: 0151000 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0942-0940 (Electronic) Linking ISSN: 00016268 NLM ISO Abbreviation: Acta Neurochir (Wien) Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Wien, Springer.
مواضيع طبية MeSH: Hydrocephalus, Normal Pressure/*diagnosis , Intracranial Pressure/*physiology, Aged ; Aged, 80 and over ; Female ; Humans ; Hydrocephalus, Normal Pressure/physiopathology ; Infusions, Intraventricular ; Male ; Middle Aged
مستخلص: Background: Infusion tests, which measure resistance to outflow (R out ), are used in selecting patients suspected for idiopathic normal pressure hydrocephalus (iNPH) for shunt surgery. Infusion tests can be performed through an external ventricular drain (EVD). A 24-hour time gap from EVD insertion to an infusion test is a routine practice at our department due to concerns that the surgical procedure might influence the test results in the immediate postoperative period. The objective of the study was to investigate if timing of an intraventricular infusion test influences the results of the test in patients suspected for iNPH.
Methods: Ten patients scheduled for an intraventricular infusion test were included. Measurements of baseline intracranial pressure (ICP) and plateau ICP were obtained during constant rate intraventricular infusion test performed at two time points (1 and 24 h after EVD insertion) and R out was calculated from these measures and compared within patients.
Results: Eight patients completed both infusion tests. In one of the 18 infusion tests performed, it was not possible to define an ICP plateau and this infusion test was excluded, leaving 7 paired infusion tests. Median R out was 12.9 mmHg/ml/min (range 7.0-22.0) 1 h after EVD insertion and 11.3 mmHg/ml/min (range 7.8-18.1) after 24 h. Overall, there were no statistically significant differences in R out (P = 0.83), baseline ICP (P = 0.70), or plateau ICP (P = 0.81) between the recordings performed 1 h and 24 h after EVD insertion. For two of the seven patients with paired infusion tests, there was poor agreement between R out values at 1 and 24 h.
Conclusion: Overall, R out estimates do not change significantly between 1 and 24 h after EVD insertion. We therefore propose that infusion tests can be performed shortly after surgery to reduce the period of indwelling EVD and duration of hospitalization.
فهرسة مساهمة: Keywords: CSF outflow; Infusion test; Intracranial pressure monitoring; Normal pressure hydrocephalus
تواريخ الأحداث: Date Created: 20200109 Date Completed: 20201109 Latest Revision: 20201109
رمز التحديث: 20231215
DOI: 10.1007/s00701-019-04168-w
PMID: 31912355
قاعدة البيانات: MEDLINE
الوصف
تدمد:0942-0940
DOI:10.1007/s00701-019-04168-w