دورية أكاديمية
أعرض في EDS

Presentation and Characteristics of Abdominal Pain Vary by Irritable Bowel Syndrome Subtype: Results of a Nationwide Population-Based Study.

التفاصيل البيبلوغرافية
العنوان: Presentation and Characteristics of Abdominal Pain Vary by Irritable Bowel Syndrome Subtype: Results of a Nationwide Population-Based Study.
المؤلفون: Shah ED; Section of Gastroenterology and Hepatology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire., Almario CV; Division of Digestive and Liver Diseases, Cedars-Sinai Medical Center, Los Angeles, California., Spiegel BM; Division of Digestive and Liver Diseases, Cedars-Sinai Medical Center, Los Angeles, California., Chey WD; Division of Gastroenterology, Michigan Medicine, Ann Arbor, Michigan.
المصدر: The American journal of gastroenterology [Am J Gastroenterol] 2020 Feb; Vol. 115 (2), pp. 294-301.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Wolters Kluwer Health Country of Publication: United States NLM ID: 0421030 Publication Model: Print Cited Medium: Internet ISSN: 1572-0241 (Electronic) Linking ISSN: 00029270 NLM ISO Abbreviation: Am J Gastroenterol Subsets: MEDLINE
أسماء مطبوعة: Publication: <2019-> : [Philadelphia, PA] : Wolters Kluwer Health
Original Publication: New York, Elsevier Science, -2003.
مواضيع طبية MeSH: Abdominal Pain/*physiopathology , Constipation/*physiopathology , Diarrhea/*physiopathology , Irritable Bowel Syndrome/*physiopathology, Abdominal Pain/etiology ; Adolescent ; Adult ; Aged ; Constipation/etiology ; Diarrhea/etiology ; Female ; Humans ; Irritable Bowel Syndrome/complications ; Male ; Middle Aged ; Pain Measurement ; Young Adult
مستخلص: Introduction: Abdominal pain is a cardinal feature of irritable bowel syndrome (IBS); however, differences in abdominal pain among IBS subtypes remain unknown. We aimed to characterize abdominal pain symptoms among established IBS subtypes using data from the National Gastrointestinal (GI) Survey.
Methods: Individuals participating in the National GI Survey completed National Institutes of Health GI Patient-Reported Outcomes Measurement Information System (GI-PROMIS) questionnaires. Adults meeting modified Rome III IBS criteria and reporting abdominal pain in the previous 7 days were eligible. Outcomes included abdominal pain severity, bothersomeness, interference with daily activities, frequency, and location. Results were stratified by subtype (diarrhea [IBS-D], constipation [IBS-C], and mixed [IBS-M]). Regression models adjusted for demographics and comorbidities.
Results: One thousand one hundred fifty-eight individuals (245 IBS-D, 232 IBS-C, and 681 IBS-M) with active IBS symptoms (defined as abdominal pain in the past 7 days) were included. Demographics were similar among the subtypes except for age, race/ethnicity, education, and marital status. The GI-PROMIS score was lower for IBS-D (percentile score of 68.6, SD = 25.1; P = 0.001) and IBS-M (69.1, SD = 25.1; P < 0.001) compared with IBS-C (75.5, SD = 20.7). Abdominal pain was more bothersome (P = 0.001), caused more interference with daily activities (P = 0.03), and was more frequent (P = 0.047) for individuals with IBS-C compared with individuals with IBS-D. No differences in these domains were seen between individuals with IBS-D and IBS-M. Individuals with IBS-C and IBS-M had more widespread pain compared with those with IBS-D.
Discussion: In this population-based study, we found that abdominal pain characteristics differ between the IBS subtypes. Namely, individuals with IBS-C experience more bothersome, frequent, and diffuse abdominal pain compared with those with IBS-D.
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معلومات مُعتمدة: UG3 AR076573 United States AR NIAMS NIH HHS; UL1 TR001881 United States TR NCATS NIH HHS
تواريخ الأحداث: Date Created: 20200109 Date Completed: 20200428 Latest Revision: 20240329
رمز التحديث: 20240329
مُعرف محوري في PubMed: PMC7469977
DOI: 10.14309/ajg.0000000000000502
PMID: 31913193
قاعدة البيانات: MEDLINE
الوصف
تدمد:1572-0241
DOI:10.14309/ajg.0000000000000502