دورية أكاديمية
Acromegaly in the elderly patient.
| العنوان: | Acromegaly in the elderly patient. |
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| المؤلفون: | Jallad RS; Unidade de Neuroendocrinologia, Serviço de Endocrinologia e Metabologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil., Bronstein MD; Unidade de Neuroendocrinologia, Serviço de Endocrinologia e Metabologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil. |
| المصدر: | Archives of endocrinology and metabolism [Arch Endocrinol Metab] 2019 Nov-Dec; Vol. 63 (6), pp. 638-645. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Segmento Farma Editores Country of Publication: Brazil NLM ID: 101652058 Publication Model: Print Cited Medium: Internet ISSN: 2359-4292 (Electronic) Linking ISSN: 23593997 NLM ISO Abbreviation: Arch Endocrinol Metab Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: São Paulo, SP : Segmento Farma Editores |
| مواضيع طبية MeSH: | Acromegaly*/diagnosis , Acromegaly*/epidemiology , Acromegaly*/physiopathology , Acromegaly*/therapy, Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Prognosis |
| مستخلص: | Acromegaly is an insidious disease, usually resulting from growth hormone hypersecretion by a pituitary adenoma. It is most often diagnosed during the 3rd to 4th decade of life. However, recent studies have shown an increase in the incidence and prevalence of acromegaly in the elderly, probably due to increasing life expectancy. As in the younger population with acromegaly, there is a delay in diagnosis, aggravated by the similarities of the aging process with some of the characteristics of the disease. As can be expected elderly patients with acromegaly have a higher prevalence of comorbidities than younger ones. The diagnostic criteria are the same as for younger patients. Surgical treatment of the pituitary adenoma is the primary therapy of choice unless contraindicated. Somatostatin receptor ligands are generally effective as both primary and postoperative treatment. The prognosis correlates inversely with the patient's age, disease duration and last GH level. Arch Endocrinol Metab. 2019;63(6):638-45. |
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| تواريخ الأحداث: | Date Created: 20200116 Date Completed: 20200218 Latest Revision: 20231003 |
| رمز التحديث: | 20240829 |
| مُعرف محوري في PubMed: | PMC10522238 |
| DOI: | 10.20945/2359-3997000000194 |
| PMID: | 31939489 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2359-4292 |
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| DOI: | 10.20945/2359-3997000000194 |