دورية أكاديمية
Recent Progress in the Synthesis of Quinolines.
| العنوان: | Recent Progress in the Synthesis of Quinolines. |
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| المؤلفون: | Xuan DD; Department of Chemistry, Institute of Natural Science, Vinh University, Vinh City, Vietnam. |
| المصدر: | Current organic synthesis [Curr Org Synth] 2019; Vol. 16 (5), pp. 671-708. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 101208457 Publication Model: Print Cited Medium: Internet ISSN: 1570-1794 (Print) Linking ISSN: 15701794 NLM ISO Abbreviation: Curr Org Synth Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Saif Zone, Sharjah, U.A.E. ; San Francisco, CA : Bentham Science Publishers, c2004- |
| مواضيع طبية MeSH: | Analgesics/*chemical synthesis , Anti-Infective Agents/*chemical synthesis , Anti-Inflammatory Agents/*chemical synthesis , Quinolines/*chemical synthesis |
| مستخلص: | Background: Quinoline-containing compounds present in both natural and synthetic products are an important class of heterocyclic compounds. Many of the substituted quinolines have been used in various areas including medicine as drugs. Compounds with quinoline skeleton possess a wide range of bioactivities such as antimalarial, anti-bacterial, anthelmintic, anticonvulsant, antiviral, anti-inflammatory, and analgesic activity. Due to such a wide range of applicability, the synthesis of quinoline derivatives has attracted a lot of attention of chemists to develop effective methods. Many known methods have been expanded and improved. Furthermore, various new methods for quinoline synthesis have been established. This review will focus on considerable studies on the synthesis of quinolines date which back to 2014. Objective: In this review, we discussed recent achievements on the synthesis of quinoline compounds. Some classical methods have been modified and improved, while other new methods have been developed. A vast variety of catalysts were used for these transformations. In some studies, quinoline synthesis reaction mechanisms were also displayed. Conclusion: Many methods for the synthesis of substituted quinoline rings have been developed recently. Over the past five years, the majority of those reported have been based on cycloisomerization and cyclization processes. Undoubtedly, more imaginative approaches to quinoline synthesis will appear in the literature in the near future. The application of known methods to natural product synthesis is probably the next challenge in the field. (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.) |
| فهرسة مساهمة: | Keywords: Friedländer synthesis; Povarov reaction; Quinolines; bioactivity; microwave; one-pot reaction; yield |
| المشرفين على المادة: | 0 (Analgesics) 0 (Anti-Infective Agents) 0 (Anti-Inflammatory Agents) 0 (Quinolines) |
| تواريخ الأحداث: | Date Created: 20200128 Date Completed: 20200723 Latest Revision: 20200723 |
| رمز التحديث: | 20221213 |
| DOI: | 10.2174/1570179416666190719112423 |
| PMID: | 31984888 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1570-1794 |
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| DOI: | 10.2174/1570179416666190719112423 |