دورية أكاديمية

Intermittent fasting and weight loss: Systematic review.

التفاصيل البيبلوغرافية
العنوان: Intermittent fasting and weight loss: Systematic review.
المؤلفون: Welton S; Researcher for the Anishinaabe Bimaadiziwin Research Program in Sioux Lookout, Ont., Minty R; Family physician practising at the Sioux Lookout Meno Ya Win Health Centre and Assistant Professor in the Division of Clinical Sciences at the Northern Ontario School of Medicine., O'Driscoll T; Assistant Professor in the Division of Clinical Sciences at the Northern Ontario School of Medicine in Sioux Lookout., Willms H; Research assistant in the Anishinaabe Bimaadiziwin Research Program., Poirier D; Primary care nurse at the Hugh Allan Clinic in Sioux Lookout., Madden S; Associate Professor in the Division of Clinical Sciences at the Northern Ontario School of Medicine in Sioux Lookout., Kelly L; Research consultant for the Sioux Lookout Meno Ya Win Health Centre. lkelly@mcmaster.ca.
المصدر: Canadian family physician Medecin de famille canadien [Can Fam Physician] 2020 Feb; Vol. 66 (2), pp. 117-125.
نوع المنشور: Journal Article; Systematic Review
اللغة: English
بيانات الدورية: Publisher: College of Family Physicians of Canada Country of Publication: Canada NLM ID: 0120300 Publication Model: Print Cited Medium: Internet ISSN: 1715-5258 (Electronic) Linking ISSN: 0008350X NLM ISO Abbreviation: Can Fam Physician Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Don Mills, Ont. : College of Family Physicians of Canada
مواضيع طبية MeSH: Fasting* , Weight Loss*, Obesity/*therapy, Body Mass Index ; Female ; Humans ; Male ; Primary Health Care/methods
مستخلص: Objective: To examine the evidence for intermittent fasting (IF), an alternative to calorie-restricted diets, in treating obesity, an important health concern in Canada with few effective office-based treatment strategies.
Data Sources: A MEDLINE and EMBASE search from January 1, 2000, to July 1, 2019, yielded 1200 results using the key words fasting, time restricted feeding, meal skipping, alternate day fasting, intermittent fasting, and reduced meal frequency .
Study Selection: Forty-one articles describing 27 trials addressed weight loss in overweight and obese patients: 18 small randomized controlled trials (level I evidence) and 9 trials comparing weight after IF to baseline weight with no control group (level II evidence). Studies were often of short duration (2 to 26 weeks) with low enrolment (10 to 244 participants); 2 were of 1-year duration. Protocols varied, with only 5 studies including patients with type 2 diabetes.
Synthesis: All 27 IF trials found weight loss of 0.8% to 13.0% of baseline weight with no serious adverse events. Twelve studies comparing IF to calorie restriction found equivalent results. The 5 studies that included patients with type 2 diabetes documented improved glycemic control.
Conclusion: Intermittent fasting shows promise for the treatment of obesity. To date, the studies have been small and of short duration. Longer-term research is needed to understand the sustainable role IF can play in weight loss.
(Copyright© the College of Family Physicians of Canada.)
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تواريخ الأحداث: Date Created: 20200216 Date Completed: 20210326 Latest Revision: 20210326
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC7021351
PMID: 32060194
قاعدة البيانات: MEDLINE