دورية أكاديمية
Rehospitalization Following Pediatric Heart Transplantation: Incidence, Indications, and Risk Factors.
| العنوان: | Rehospitalization Following Pediatric Heart Transplantation: Incidence, Indications, and Risk Factors. |
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| المؤلفون: | Lambert AN; Pediatric Cardiology, Monroe Carell Jr. Children's Hospital At Vanderbilt, Nashville, TN, USA. andrea.n.lambert@vumc.org.; Department of Pediatric Cardiology, Monroe Carell Jr. Children's Hospital, Vanderbilt University, 2200 Children's Way, Suite 5230 DOT, Nashville, TN, 37232-9119, USA. andrea.n.lambert@vumc.org., Weiner JG; Pediatric Cardiology, Monroe Carell Jr. Children's Hospital At Vanderbilt, Nashville, TN, USA., Hall M; Children's Hospital Association, Lenexa, KS, USA., Thurm C; Children's Hospital Association, Lenexa, KS, USA., Dodd DA; Pediatric Cardiology, Monroe Carell Jr. Children's Hospital At Vanderbilt, Nashville, TN, USA., Bearl DW; Pediatric Cardiology, Monroe Carell Jr. Children's Hospital At Vanderbilt, Nashville, TN, USA., Soslow JH; Pediatric Cardiology, Monroe Carell Jr. Children's Hospital At Vanderbilt, Nashville, TN, USA., Feingold B; Pediatrics and Clinical and Translational Science, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Smith AH; Pediatric Cardiology, Monroe Carell Jr. Children's Hospital At Vanderbilt, Nashville, TN, USA.; Pediatric Critical Care, Monroe Carell Jr. Children's Hospital At Vanderbilt, Nashville, TN, USA., Godown J; Pediatric Cardiology, Monroe Carell Jr. Children's Hospital At Vanderbilt, Nashville, TN, USA. |
| المصدر: | Pediatric cardiology [Pediatr Cardiol] 2020 Mar; Vol. 41 (3), pp. 584-590. Date of Electronic Publication: 2020 Feb 26. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Springer Verlag Country of Publication: United States NLM ID: 8003849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1971 (Electronic) Linking ISSN: 01720643 NLM ISO Abbreviation: Pediatr Cardiol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: New York Ny : Springer Verlag Original Publication: [New York, Springer-Verlag] |
| مواضيع طبية MeSH: | Heart Transplantation/*adverse effects , Patient Readmission/*statistics & numerical data, Case-Control Studies ; Child ; Child, Preschool ; Databases, Factual ; Female ; Heart Transplantation/statistics & numerical data ; Humans ; Incidence ; Infant ; Infant, Newborn ; Male ; Postoperative Complications/epidemiology ; Retrospective Studies ; Risk Factors |
| مستخلص: | Rehospitalization following pediatric heart transplantation is common. However, existing data remain somewhat limited. Using a novel linkage between administrative and clinical databases, pediatric heart transplant (HT) recipients from 29 centers who survived to discharge were retrospectively reviewed to determine the frequency, timing of, and indication for all-cause rehospitalizations in the year following transplant discharge. Of 2870 pediatric HT recipients, 1835 (63.9%) were rehospitalized in the first year post-discharge (5429 total readmissions). Rehospitalization rates varied significantly across centers (46% to 100%) and were inversely correlated to center transplant volume (r 2 0.25, p < 0.01). The median number of rehospitalizations per patient was 2 (IQR 1-4) and the median time to first rehospitalization was 29 days (IQR 9-99 days). Independent risk factors for rehospitalization included younger age at HT (HR 0.99, 95% CI 0.97-0.99), congenital heart disease (HR 1.2, 95% CI 1.1-1.4), listing status 1B at transplant (HR 1.3, 95% CI 1.1-1.5), and post-transplant complications including rejection prior to discharge (HR 1.5 95% CI 1.3-1.8) and chylothorax (HR 1.3, 95% CI 1.0-1.6). Cardiac diagnoses were the most common indication for rehospitalization (n = 1600, 29.5%), followed by infection (n = 1367, 25.2%). These findings may serve to guide the development of interventions aimed at reducing post-HT hospitalizations. |
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| معلومات مُعتمدة: | T32 HL105334 United States HL NHLBI NIH HHS; T32HL105334 National Heart, Lung, and Blood Institute of the National Institutes of Health |
| فهرسة مساهمة: | Keywords: Hospital readmission; Pediatric heart transplant; Rehospitalization |
| تواريخ الأحداث: | Date Created: 20200228 Date Completed: 20200831 Latest Revision: 20200831 |
| رمز التحديث: | 20240829 |
| مُعرف محوري في PubMed: | PMC7176534 |
| DOI: | 10.1007/s00246-020-02326-x |
| PMID: | 32103290 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1432-1971 |
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| DOI: | 10.1007/s00246-020-02326-x |