دورية أكاديمية
Concordance among in vivo reflectance confocal microscopy, trichoscopy, and histopathology in the evaluation of scalp discoid lupus.
| العنوان: | Concordance among in vivo reflectance confocal microscopy, trichoscopy, and histopathology in the evaluation of scalp discoid lupus. |
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| المؤلفون: | Melo DF; Dermatology Department, University of State of Rio de Janeiro (UERJ), Rio de Janeiro, Brazil.; Dermatology Department, Marcílio Dias Naval Hospital, Rio de Janeiro, Brazil., De Carvalho N; Dermatology Department, University of Modena and Reggio Emilia, Modena, Italy., Ardigò M; Clinical Dermatology, San Galicano Dermatology Institute-IRCCS, Rome, Italy., Pellacani G; Dermatology Department, University of Modena and Reggio Emilia, Modena, Italy., Mota ANCM; Dermatology Department, University of State of Rio de Janeiro (UERJ), Rio de Janeiro, Brazil.; Dermatology Department, Central Aeronautics Hospital, Rio de Janeiro, Brazil., Barreto TM; Dermatology Department, Marcílio Dias Naval Hospital, Rio de Janeiro, Brazil., Jorge Machado C; Preventive and Social Medicine Department, Federal University of Minas Gerais, Belo Horizonte, Brazil., Pineiro-Maceira JM; Dermatology Department, University of State of Rio de Janeiro (UERJ), Rio de Janeiro, Brazil., Barcaui CB; Dermatology Department, University of State of Rio de Janeiro (UERJ), Rio de Janeiro, Brazil. |
| المصدر: | Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) [Skin Res Technol] 2020 Sep; Vol. 26 (5), pp. 675-682. Date of Electronic Publication: 2020 Mar 20. |
| نوع المنشور: | Journal Article; Observational Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: Blackwell Country of Publication: England NLM ID: 9504453 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0846 (Electronic) Linking ISSN: 0909752X NLM ISO Abbreviation: Skin Res Technol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <1998-> : Oxford : Blackwell Original Publication: Copenhagen, Denmark ; Cambridge, MA : Munksgaard, c1995- |
| مواضيع طبية MeSH: | Lupus Erythematosus, Discoid*/diagnostic imaging , Microscopy, Confocal* , Scalp*/diagnostic imaging, Cross-Sectional Studies ; Humans ; Reproducibility of Results |
| مستخلص: | Background: Reflectance confocal microscopy (RCM) has been used for the evaluation of several inflammatory skin conditions, including skin discoid lupus erythematosus (DLE), and has been correlated with conventional histopathology (HP). However, RCM is not being widely used in trichology. Few reports and just preliminary data suggest the use of RCM as a complementary tool in alopecias. Objectives: To correlate the major RCM features of scalp DLE with trichoscopy and HP findings of biopsy specimens obtained from the same lesions. Methods: This is an observational, analytical, and cross-sectional study involving 12 patients with a clinically established diagnosis of scalp DLE. Patients underwent global clinical photograph, trichoscopy, and RCM examination in the same site followed by two 4-mm punch biopsy specimens for HP analysis. Inter-methods agreement among RCM imaging, trichoscopy, and horizontal histopathology sections (HHS) were calculated using Cohen Kappa (k) statistics. Results: Statistical analysis of the agreement between RCM and HP features disclosed an overall agreement similar to skin DLE. Seven of the eleven features evaluated had agreement superior to 75%. We also evaluated RCM features associated with three of their corresponding trichoscopic findings for further investigation of their agreement with HP. Statistical analysis showed an enhancement with agreement of 86% when the non-invasive techniques are used together. Conclusion: Consistent correlation between RCM and HP observed in our study supports the reliability of RCM in the diagnosis of scalp DLE. RCM may be considered a promising tool for scalp DLE microscopic evaluation and presents similar RCM features to DLE in other body sites. By associating clinical, trichoscopic and RCM evaluation, dermatologists will have a non-invasive arsenal for the assessment of hair and scalp disorders, benefiting patients. (© 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.) |
| References: | Lacarrubba F, Verzì AE, Caltabiano R, Broggi G, Di Natale A, Micali G. Discoid lupus erythematosus: Reflectance confocal microscopy features correlate with horizontal histopathological sections. Skin Res Technol. 2019;25(2):242-244. Wassef C, Mateus R, Rao BK. In vivo reflectance confocal microscopy features of discoid lupus erythematosus. J Drugs Dermatol. 2012;11(9):1111-1113. Ardigò M, Maliszewski I, Cota C, et al. Preliminary evaluation of in vivo reflectance confocal microscopy features of discoid lupus erythematosus. Br J Dermatol. 2007;156(6):1196-1203. Ardigò M, Agozzino M, Franceschini C, et al. Reflectance confocal microscopy for scarring and non- scarring alopecia real-time assessment. Arch Dermatol Res. 2016;308(5):309-318. Rudnicka L, Olszewska M, Rakowska A, Slowinska M. Trichoscopy update 2011. J Dermatol Case Rep. 2011;5(4):82-88. Lacarrubba F, Micali G, Tosti A. Scalp dermoscopy or trichoscopy. Curr Probl Dermatol. 2015;47:21-32. Białek-Galas K, Wielowieyska-Szybińska D, Dyduch G, Wojas-Pelc A. The use of reflectance confocal microscopy in selected inflammatory skin diseases. Pol J Pathol. 2015;66(2):103-108. Ardigo M, Cota C, Berardesca E, Gonzalez S. Concordance between in vivo reflectance confocal microscopy and histology in the evaluation of plaque psoriasis. J Eur Acad Dermatol Venereol. 2009;23:660-667. Agozzino M, Tosti A, Barbieri L, et al. Confocal microscopic features of scarring alopecia: preliminary report. Br J Dermatol. 2011;165:534-540. Koller S, Gerger A, Ahlgrimm-Siess V, et al. In vivo reflectance confocal microscopy of erythematosquamous skin diseases. Exp Dermatol. 2009;18(6):536-540. Ardigò M, Tosti A, Cameli N, Vincenzi C, Misciali C, Berardesca E. Reflectance confocal microscopy of the yellow dot pattern in alopecia areata. Arch Dermatol. 2011;147:61-64. Rudnicka L, Olszewska M, Rakowska A. In vivo reflectance confocal microscopy: usefulness for diagnosing hair diseases. J Dermatol Case Rep. 2008;2(4):55-59. Cinotti E, Perrot JL, Labeille B, Raberin H, Flori P, Cambazard F. Hair dermatophytosis diagnosed by reflectance confocal microscopy: six cases. J Eur Acad Dermatol Venereol. 2015;29(11):2257-2259. Agozzino M, Berardesca E, Donadio C, et al. Reflectance confocal microscopy features of seborrheic dermatitis for plaque psoriasis differentiation. Dermatology. 2014;229:215-221. Rajadhyaksha M, Marghoob A, Rossi A, Halpern AC, Nehal KS. Reflectance confocal microscopy of skin in vivo: From bench to bedside. Lasers Surg Med. 2017;49(1):7-19. Miteva M. A comprehensive approach to hair pathology of horizontal sections. Am J Dermatopathol. 2013;35(5):529-540. Gwet K. Handbook of Inter-Rater Reliability: The Definitive Guide to Measuring the Extent of Agreement Among Multiple Raters (3rd edn). Gaithersburg, MD: Advanced Analytics, LLC; 2012. Altman DG. Practical Statistics for Medical Research. London, UK: Chapman and Hall; 1991. Ardigò M, El Shabrawi-Caelen L, Tosti A. In vivo reflectance confocal microscopy assessment of the therapeutic follow-up of cutaneous T-cell lymphomas causing scalp alopecia. Dermatol Ther. 2014;27:248-251. Amini-Adle M, Debarbieux S, Perier-Muzet M, et al. Signet ring-Like cells: a new reflectance confocal microscopy clue of interface dermatitis correlated to basal cell vacuolization in histopathology. Dermatology. 2016;232(1):83-85. Benati E, Longo C, Piana S, Moscarella E. Preliminary evaluation of reflectance confocal microscopy features of scalp melanoma. Australas J Dermatol. 2017;58(4):312-316. |
| فهرسة مساهمة: | Keywords: alopecia; imaging technique; lupus erythematosus; reflectance confocal microscopy; trichoscopy |
| تواريخ الأحداث: | Date Created: 20200321 Date Completed: 20210813 Latest Revision: 20210813 |
| رمز التحديث: | 20240829 |
| DOI: | 10.1111/srt.12852 |
| PMID: | 32196776 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1600-0846 |
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| DOI: | 10.1111/srt.12852 |